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排序方式: 共有187条查询结果,搜索用时 15 毫秒
1.
Mehmet Oguz Yenidunya Mustafa Erol Demirseren Serdar Gorkem Bulent Adil Tasbas Candemir Ceran 《European journal of plastic surgery》2007,29(7):327-330
Nonunion in the forearm following a radioulnar fracture is one of the nightmares of the orthopedic surgeon. Fortunately, it
is rare. We treated a large bone defect of the forearm, using a vascularized fibular graft after excision of the unhealed
bone segment in a 10-year-old boy with neurofibromatosis. This situation followed a double fracture that had been operated
on several times using conventional methods. Following the debridement of the unhealthy tissues in the pseudoarthrotic region,
the vascularized fibula was placed on the dorsal surface of the proximal radius fragment. The distal fragment of the radius
was inserted into the fibular cavity and fixation was established with a Kirschner wire distally and with a plate proximally.
Only two screws were used to fix the plate. The peroneal artery was anastomosed with the radial artery; one of its venae comitantes
was anastomosed with the cephalic vein in an end-to-end fashion. After surgery, the elbow was immobilized at 90 degrees of
flexion with a splint for 6 weeks. One year after surgery, forearm stabilization and elbow and hand functions were very satisfactory.
However, because the distal epiphyses of the bones were destroyed following the repeated surgery and the original trauma itself,
a very prominent difference between the two forearms occurred, suggesting the need for bone lengthening in the future. By
presenting this case we would like to conclude that one can expect good bone healing with a vascularized bone transfer in
these cases when there is not enough space to place screws, but support can be provided by an external splint and K wire. 相似文献
2.
Gorkem Aksu MD Merdan Fayda Burak Sakar Yersu Kapran 《Journal of gastrointestinal cancer》2003,34(2-3):73-77
Blood-borne metastases to the kidneys from solid tumors have received little attention in the medical literature because they usually occur in a setting of advanced systemic disease, and renal involvement is a elatively minor cause of symptoms. Although the frequency of metastases to the kidney in cancer patients is 7–13% in large autopsy series, incidental discovery of a renal metastasis as the first manifestation of a primary tumor is a very rare event. The most common primary malignancy to involve the kidney is bronchogenic carcinoma, followed by breast and gastrointestinal cancers. In this article, we report a patient with left colon cancer and isolated metastasis to the right kidney at the time of initial diagnosis. Left hemicolectomy and right nephrectomy were performed. Adjuvant systemic chemotherapy consisting of 5-fluorouracil (5-FU) and folinic acid (FA) was given. 5-FU and FA were stopped after four cycles because metastases to the lung and liver occurred about 3 mo after the surgery during adjuvant chemotherapy. Capecitabine was started. The patient died 9 mo after the discovery of the isolated renal metastasis. Nephrectomy is more for diagnostic clarification in the setting of synchronous primary because it has no effect on survival and its effect on quality of life is minimal; as seen in our case, the other organ metastases rapidly occur and the survival is limited. Nephrectomy may also compromise the choice of chemotherapy agents that require renal clearance, thus a careful evaluation of renal functions is necessary if a nephrectomy is performed. In the matter of a decreased renal clearance, the doses of these drugs should be decreased or the choice should be reevaluated. 相似文献
3.
4.
Sebnem Egriboyun Gamze Ugurluer Funda Vesile Corapcioglu Levent Celik Gorkem Gungor Banu Atalar Enis Ozyar 《Journal of Medical Imaging and Radiation Sciences》2021,52(2):305-311
Extracranial malignant rhabdoid tumors are rare and aggressive tumors that typically occur in the pediatric age group and have a poor prognosis. Herein, we report a case of a one year and five months old male infant who was referred with the diagnosis of malignant rhabdoid tumor of the liver. Magnetic resonance guided stereotactic body radiotherapy was administered with concomitant chemotherapy. Treatment was well tolerated with no severe acute side effects. A 40.8% volumetric reduction of the tumor was observed at the last fraction of MR guided radiotherapy. 相似文献
5.
Radiotherapy (XRT) is a curative treatment option for prostate cancer (PCa). Recent XRT technologies allow higher dose therapy that lead to increased local control with less adjacent tissue damage. Additionally, receiving neo-adjuvant or adjuvant hormonotherapy (HT) during radiation therapy increases the curative effect. The aim of this paper is to review the current literature and guidelines on external beam radiation therapy for PCa. However, brachytherapy and radiosurgery, a recently evolving relatively new technology for the radiotherapeutic management of localized PCa, are beyond the scope of this paper. 相似文献
6.
Ferit Kerim Kucukler Umit Gorkem Yasin Simsek Ramazan Kocabas Sebnem Gulen Serdar Guler 《Gynecological endocrinology》2016,32(9):759-761
Introduction: Gestational diabetes mellitus (GDM) occurs in ~10–25% of pregnancies. Nesfatin-1, plays a role in carbohydrate metabolism by inhibiting glucagon secretion, besides has a glucose-dependent insulinotropic effect. Explanation of the GDM pathogenesis is important due to preventing gestational complications. We aimed to investigate relationship between GDM and Nesfatin-1.Material and methods: Seventy-nine pregnant subjects were randomly allocated to either GDM group (GDG, n?=?38) or control group (CG, n?=?41). For GDM diagnosis, 50 and 100?g oral glucose tolerance test (OGTT) were used. Nesfatin-1, insulin and other parameters were measured for all subjects. The homeostasis model assessment-insulin resistance (HOMA-IR) was calculated.Results: Nesfatin-1 was found lower and insulin was found higher in GDG than CG. Negative correlation has been founded between Nesfatin-1 with weight, BMI, fasting glucose, serum glucose level at first hour of the 50?g OGTT and HOMA-IR.Conclusion: In this study, patients with GDM had lower Nesfatin-1 levels than without GDM. Therefore, when the Nesfatin-1 effects on the GDM pathogenesis is clear, it may be contributed to diagnosis and treatment of the GDM. 相似文献
7.
Mrzljak Anna Dinjar-Kujundzic Petra Knotek Mladen Kudumija Boris Ilic Mario Gulin Marijana Zibar Lada Hrstic Irena Jurekovic Zeljka Kolaric Branko Jemersic Lorena Prpic Jelena Tomljenovic Morana Vilibic-Cavlek Tatjana 《International urology and nephrology》2020,52(2):371-378
International Urology and Nephrology - Data on the seroprevalence of hepatitis E virus (HEV) in heamodialysis (HD) patients are conflicting, ranging from 0 to 44%. The aim of this study was to... 相似文献
8.
Gorkem Karakas Ugurlu Sukran Erten Mustafa Ugurlu Ali Caykoylu Alpaslan Altunoğlu 《Sexuality and disability》2014,32(2):197-204
Primary Sjögren’s syndrome causes disability and impaired quality of life. However, unlike other rheumatological diseases, primary Sjögren’s syndrome affects the exocrine glands and can impact on sexual health. Primary Sjögren’s syndrome is also associated with depression. Two groups of female patients were included in the present study; one group comprised patients with primary Sjögren’s syndrome and the second group consisted of healthy women. The two groups were compared in terms of female sexual dysfunction using the Female Sexual Function Index and depression using the Beck Depression Inventory. Path analysis was used to show the relationship between primary Sjögren’s syndrome, depression and female sexual dysfunction. Depression and female sexual dysfunction were higher in the group with primary Sjögren’s syndrome than in the group of healthy women. Path analysis confirmed that primary Sjogren’s syndrome itself and primary Sjögren’s syndrome induced depression may lead to female sexual dysfunction. Both female sexual dysfunction and depression are common in primary Sjögren’s syndrome. Therefore, it is important to consider the broad clinical picture for patients with primary Sjögren’s syndrome, as both female sexual dysfunction and depression can be treated with education, psychotherapy, or medicine. 相似文献
9.
Mehmet Serdar Kutuk Laure Croisille Sureyya Burcu Gorkem Ebru Yilmaz Levent Korkmaz Philippe Bierling Ekrem Unal 《Child's nervous system》2014,30(12):2147-2150
Background
Maternal autoimmune thrombocytopenic purpura (AITP) can cause fetal intracranial hemorrhage.Case report
A 19-year-old primigravida was referred to our institution for prenatally detected ventriculomegaly at 30th week of gestation. Her personal and family histories were unremarkable. Her platelet count was 54?×?109/L. Fetal neurosonography showed intraparenchymal hemorrhage. AITP was diagnosed in the mother and platelet count decreased at 34?×?109/L. Patient was treated with methylprednisolone and intravenous immunoglobulin. She delivered a 2,340-g infant at 37 weeks with elective cesarean section. The platelet count of the newborn was 181?×?109/L and coagulation tests were normal. No antiplatelet specific antibodies were detected in cord blood. Postnatal MRI evaluation confirmed grade IV intracranial hemorrhage. The newborn baby has suffered from mild spasticity and seizures.Conclusions
Clinicians must be vigilant about the catastrophic fetal complications of maternal AITP; a close follow-up with a multidisciplinary cooperation between obstetricians, hematologists, and neonatologists must be warranted. 相似文献10.