Normal childbirth following total laryngectomy

A case of carcinoma of the supraglottic larynx, who had a normal childbirth after total laryngectomy, is presented. This is extremely rare, because of the absence of glottic closure which fixes the cheset wall during the bearing down pains of normal labour.     

Transglottic carcinoma with intracranial metastases

A sixty year old patient underwent radical Radiotherapy for a transglottic laryngeal carcinoma and the primary site was free of disease 6 weeks later. The initial work up showed a clear roentgenogram of the chest and the vertebral architecture was normal. The patient had neurological symptoms few months later and a diagnostic CT Scan of brain showed intracranial metastases. Locally he was disease free as in the chest. After a palliative course of radiotherapy of the brain, the patient expired. The probable route of spread was discussed.     

Role of micro-nutrients and trace elements in carcinoma of larynx

Cancer of the larynx is fourteenth most common cancer in the world. Evidence from case-control studies conducted in developed as well as developing countries suggest that specific micro-nutrients and trace elements have been implicated to be significantly associated with laryngeal carcinoma. The association of these micro-nutrients and trace elements with laryngeal cancer has been discussed in this review article.     

Age-related changes in the total protein in the brain of Periplaneta americana (L.)

Quantitative changes in the total protein in the brain of aging male and female Periplaneta americana have been observed. A significant increase of total protein and neurosecretory cells in the brain up to 5 months, followed by a considerable decline in later age, points to a direct relationship between the neurosecretory cell number and reproductive phenomenon. Higher total protein concentration and cell number maintain reproduction up to 5 months while a decline after 6 months of adult life adversly affects reproduction. This suggests that neurosecretory cell number and protein concentration are related to reproduction and thereby aging.     

Liver profile in COVID-19: a meta-analysis

Journal of Public Health - Few studies have been performed to investigate multiorgan failure occurring with extrapulmonary symptoms like diarrhea, anorexia, and vomiting. There has been no attempt...     

The clinical radiological and histological correlation of orbital assessment in malignant lesions of the maxillo-ethmoid complex

Twelve patients undergoing surgery between May 1995 and March 1999 for malignant tumours of the paranasal sinuses abutting or invading the orbital walls were studied for the need to remove orbital contents. Alt patients were evaluated clinically, radiologically (CT Scan) and per-operatively to delineate the extent of orbital invasion. Combined regimen (Surgery + Radiotherapy) were used in all patients. A biopsy from periorbita was taken when eye was spared. It was found that per-operative evaluation of the orbit is equally specific in comparision to clinical and CT Scan combined and eye may be preserved in selected patients with involvement of orbital periosteum provided there is no frank soft tissue mass in the orbit.     

Role of lateral neck dissection in cancers of the larynx and hypopharynx with No neck

Radical neck dissection is a standard procedure carried out for the teatment of palpable nodes in the neck but if carried out electively in cases where there are no palpable nodes in the neck it is considered to be an overtreatment with its associated morbity. Lateral neck dissection was carried out on twenty patients who had T31 T4 lesion of the larynx and hypophar-vnx with NO neck. The dissection entails removal of Level II. III and IV nodes. Occult metastasis 80% and 85% respectively. The mean follow up was 13 monts. It appears from our study that elective lateral neck dissection is a promising and safe procedure and may be useful as an important prognostic tool in sampling the lymph nodes and predicting recurrences in the neck.     

Cystosarcoma phyllodes: Our institutional experience

Twenty‐six patients of Cystosarcoma phyllodes, treated between July 1994 and July 2001, were analysed retrospectively. Median age at presentation was 38 years (range 13?61 years). Mean size of the lesion was 6 cm. There were 77% left‐sided lesions and 23% right‐sided lesions. Histologically, 58% lesions were benign, 11% borderline and 31% malignant lesions. All patients underwent definitive surgical procedure in the form of wide local excision or mastectomy. Four patients received postoperative radiotherapy. Median follow‐up period was 35 months. Six patients showed recurrence, and four of these were malignant. Median disease‐free survival period was 34 months.