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排序方式: 共有511条查询结果,搜索用时 15 毫秒
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Carmen de Casso Muralidhar Lalam Sudip Ghosh Michael Timms 《Otolaryngology--head and neck surgery》2006,134(2):288-293
OBJECTIVE: To evaluate the procedure in terms of technical difficulties, patient satisfaction, symptom relief, recurrence, and further management. STUDY DESIGN: Retrospective study including 41 patients who underwent endoscopic stapling diverticulotomy. Clinical notes were reviewed, and patients were sent a patient satisfaction questionnaire. Statistical analysis was done using the chi(2) square test. SETTING: Teaching hospital. RESULTS: Larger pouches had the best results; 81.578% were satisfied with the surgery, and 86.84% had improved swallowing. Complications presented in 6 patients (15%), including a perforated pouch and an esophageal perforation. Complications were more frequent in small pouches. CONCLUSIONS AND SIGNIFICANCE: Endoscopic stapling diverticulotomy offers rapid recovery in most patients, with early oral intake and short hospital stay. There is a high degree of symptoms relief, and the patient's satisfaction rate is high. The assessment of the pharyngeal pouch size is an important factor when deciding the best management for a patient with a pharyngeal pouch. 相似文献
3.
Satyanarayana S Kalghatgi AT Malaviya AK Bhardwaj JR Muralidhar A Jawed KZ Chatterjee T Trehan A Sirohi D 《Indian journal of pathology & microbiology》2003,46(3):416-419
The value of autopsy in understanding the natural course of any disease is beyond any argument. The reluctance of pathologists to perform autopsy in HIV infected cadavers is justified due to the risks involved to the prosector and the morgue attendants. A relative low risk needle necropsy protocol is proposed using fine needle aspiration cytology, tru-cut biopsies and microbiological examination. Diagnosis could be offered in all the forty-four needle necropsies performed. Disseminated tuberculosis in 18/44 (40.9%) cases, disseminated cryptococcosis in 12/44 (27.2%) cases, poly-microbial infections in 27.2% cases and non-Hodgkin's lymphoma in 9% cases were detected in the study. Infectious agents like Histoplasma capsulatum, Isospora belli, tachyzoites of Toxoplasma gondii, Candida sp and Cryptococcus sp could be demonstrated in the samples obtained in the study. Lack of material for study of gross pathology, inaccessibility of deep-seated lesions and risk of needle stick injury to the prosector though low are the limitations of this procedure. 相似文献
4.
Dayananda S Sharma Rakesh Jalali Chandrashekhar M Tambe Deepak D AnimeshDeshpande 《Radiotherapy and oncology》2004,70(1):49-54
BACKGROUND AND PURPOSE: The aim of this work was to measure the dose to foetus both in vivo and in vitro during three-dimensional conformal radiation therapy (3DCRT) in a pregnant patient with a pituitary adenoma. The study was then extended to assess the components contributing to the foetal dose such as collimator scatter, internal scatter, head leakage, wedge scatter and multileaf collimator (MLC) effect. PATIENTS AND METHODS: A 30-year-old pregnant woman with a non-functioning pituitary macroadenoma was planned for 3DCRT with 6MV X-ray using four equally weighted MLC-shaped non-coplanar wedged portals. In vivo dosimetry was carried out using thermoluminescent (TL) phosphor powder, which was placed at different positions on the patient, corresponding to different locations in the uterus and also at external os. In vitro measurements were also performed on a simulated phantom using the same set-up parameters and beam arrangement to verify the in vivo measured dose. Experiments were carried out to measure the respective contributions of different components towards peripheral dose. RESULTS: In vitro measured dose to foetus was found to be slightly more than that of in vivo measurement with a maximum of 0.044% of the prescribed dose of 45Gy, which corresponded to 0.0199+/-0.0008Gy. Thermoluminescence dosimeter (TLD) kept at the external os of the patient showed a dose of 0.031% of the prescribed dose. Among the various components of the peripheral dose (foetal dose) measured, head leakage was found to be the leading cause contributing 52%, followed by wedge scatter (31%), collimator scatter (14%) and internal scatter (13%). The use of MLC reduced not only the volume of normal brain irradiation as compared to open fields but also the peripheral dose by 10%. CONCLUSION: Radiotherapy of brain tumours during pregnancy poses a unique clinical situation and decisions to deliver radiotherapy should be taken after detailed in vitro and in vivo dosimetric measurements. Our findings suggest that the beam arrangement using 3-4-fields generally used for 3DCRT of brain tumour with MLC for optimal coverage can be employed for pregnant patients even in early trimester. A possible increase in foetal dose from wedges to a large extent can be compensated with the use of MLC. 相似文献
5.
Christine Nadeau DMD Arthur S. Kuperstein DDS Muralidhar Mupparapu DMD MDS Eric T. Stoopler DMD FDS RCSEd 《Special care in dentistry》2013,33(5):255-259
Pseudoxanthoma elasticum (PXE) is a disorder characterized by progressive degeneration of elastic fibers and ectopic mineralization. Cutaneous manifestations are a hallmark of this disease and organs that may be affected by the disease process include cardiovascular, central nervous system, ocular and gastrointestinal systems. Oral manifestations of PXE have been previously reported as intramucosal nodules observed on various intraoral surfaces. We present a case of a 46‐year‐old female with PXE diagnosed with temporomandibular disorder (TMD). To our knowledge, this is the first report of a patient with TMD coexisting with PXE in the scientific literature. 相似文献
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Sudha Vidyasagar Nataraj Muralidhar Varma C. K. Prashanth Yeshwanth Rao B. Kavitha 《International journal of diabetes in developing countries.》2011,31(3):161-165
Data from UKPDS study suggests that the onset of ß cell dysfunction in diabetes occurs well before the development of hyperglycemia. To study the concept of secondary OHA failure in type 2 diabetes patients of more than 10 years duration in a tertiary care hospital. A retrospective analysis of all the cases of type 2 diabetes mellitus of more than 10 years duration from 2002 to 2003 was done and the data was divided into three groups: oral hypoglycemic agents (OHA) only, Insulin only, OHA + insulin. ANOVA/Students t test was the primary statistical test used. Odds ratio and 95% CI were calculated to compare risks of other diseases and drug use. 62.35% were on only OHAs, 8.82% on only insulin and 28.82% on both insulin and OHAs. This confirms good efficacy of OHAs. Diabetic population in our study tends to have a preserved beta cell function and secondary OHA failure is a late feature. 相似文献
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Ashok Kumar Reddy Raja Rami Reddy Muralidhar Rao Paruvelli Srinivas Ambatipudi Alka Rani Sikander A. K. Lodhi Juturi Maruthi Lokabhi Reddy K. Ramakanth Reddy Niraj Pandey Rituraj Videkar Manish Kumar Sinha Ajit Babu Majji Nilanjana Deb-Jorder Atul Kumar Sahu Jyostna Myneni Anina Abraham 《International ophthalmology》2015,35(1):37-42
10.
The mechanism whereby the reciprocal relationship between the plasma levels of prolactin and HL is maintained in lactating rats under different degrees of suckling stimulus has been investigated in the present study. Plasma levels of luteinizing hormone (LH) in lactating rats suckling two pups could be reduced significantly by injecting prolactin (PRL). This reduction was also evident in ovariectomized and ovariectomized-adrenalectomized lactating rats, thus excluding mediation of the inhibitory effect by steroids from end-organs. The in vivo response of the pituitary to exogenous LHRH was lower in rats suckling eight pups than those suckling two pups. Prolactin administered prior to LHRH caused an inhibition of the response of the pituitary to exogenous LHRH in rats suckling two pups. These data provide evidence for the hypothesis that in the lactating rat, in the presence of minimal suckling stimulus, the causative factor for reducing serum LH levels is prolactin, which acts by altering the pituitary responsiveness to LHRH. 相似文献