运动对去卵巢大鼠腰椎抗压性能的影响

目的 探讨运动对去卵巢大鼠腰椎抗压性能的影响。方法 Sprague—Dawley大鼠随机分为假手术组、去卵巢手术组、雌激素治疗组和运动组，观察去卵巢大鼠经过3个月有氧跑步训练后第3腰椎抗压性能的变化。结果 运动能使去卵巢大鼠的腰椎抗压性能略有提高，但运动组压力峰值和最大抵抗应力与去卵巢手术组比较，差异均无统计学意义（P〉0．05）。结论 运动对骨质疏松夫鼠力学性能的改善作用较微弱，对其骨的保护作用弱于雌激素。     

Visual evoked potential in RCS rats with Okayama University-type retinal prosthesis (OUReP™) implantation

Photoelectric dye-coupled polyethylene film, designated Okayama University type-retinal prosthesis or OUReP?, generates light-evoked surface electric potentials and stimulates neurons. The dye-coupled films or plain films were implanted subretinally in both eyes of 10 Royal College of Surgeons rats with hereditary retinal dystrophy at the age of 6 weeks. Visual evoked potentials in response to monocular flashing light stimuli were recorded from cranially-fixed electrodes, 4 weeks and 8 weeks after the implantation. After the recording, subretinal film implantation was confirmed histologically in 7 eyes with dye-coupled films and 7 eyes with plain films. The recordings from these 7 eyes in each group were used for statistical analysis. The amplitudes of visual evoked potentials in the consecutive time points from 125 to 250 ms after flash were significantly larger in the 7 eyes with dye-coupled film implantation, compared to the 7 eyes with plain film implantation at 8 weeks after the implantation (P?<?0.05, repeated-measure ANOVA). The photoelectric dye-coupled polyethylene film, as retinal prosthesis, gave rise to visual evoked potential in response to flashing light.     

Behavior tests and immunohistochemical retinal response analyses in RCS rats with subretinal implantation of Okayama-University-type retinal prosthesis

We have developed a photoelectric dye-coupled polyethylene film as a prototype of retinal prosthesis, which we named Okayama University-type retinal prosthesis. The purposes of this study are to conduct behavior tests to assess vision in Royal College of Surgeons (RCS) rats that underwent subretinal implantation of the dye-coupled film and to reveal retinal response to the dye-coupled film by immunohistochemistry. Polyethylene films were made of polyethylene powder at refined purity, and photoelectric dyes were coupled to the film surface at higher density compared with the prototype. Either dye-coupled film or dye-uncoupled plain film used as a control was implanted subretinally from a scleral incision in both eyes of an RCS rat at 6 weeks of the age. Behavior tests 2, 4, 6, and 8 weeks after implantation were conducted by observing head turning or body turning in the direction consistent with clockwise or counterclockwise rotation of a black-and-white-striped drum around a transparent cage housed with the rat. After the behavior tests at 8 weeks, rats’ eyes were enucleated to confirm subretinal implantation of the films and processed for immunohistochemistry. In the behavior tests, the number of head turnings consistent with the direction of the drum rotation was significantly larger in RCS rats with dye-coupled- compared with plain-film implantation [P < 0.05, repeated-measure analysis of variance (ANOVA), n = 7]. The number of apoptotic neurons was significantly smaller in eyes with dye-coupled- compared with plain-film implantation (P < 0.05, Mann–Whitney U test, n = 6). In conclusion, subretinal implantation of photoelectric dye-coupled films restored vision in RCS rats and prevented the remaining retinal neurons from apoptosis.     

论中医小儿体质理论与儿童体育保健

依据中医小儿体质学说原理,分类研究小儿体质特点,认为不同体质的儿童对体育运动的易感性、耐受性和需求性是不同的,提出了"因质制宜"的儿童体育保健方案。按质分类进行的儿童体育保健,体现了中医学"辩质保健"的特色,对预防疾病的发生,保证小儿的健康成长,提高人口质量起着重要的作用。     

论中医小儿体质理论与儿童体育保健

依据中医小儿体质学说原理,分类研究小儿体质特点,认为不同体质的儿童对体育运动的易感性、耐受性和需求性是不同的,提出了“因质制宜”的儿童体育保健方案。按质分类进行的儿童体育保健,体现了中医学“辩质保健”的特色,对预防疾病的发生,保证小儿的健康成长,提高人口质量起着重要的作用。