丹参注射液与异甘草酸镁抗肝纤维化的临床对比研究

Objective To observe the change of liver function and liver fibrosis indexes of the chronic hepatitis B patients that were treated by Danshen injection(DI) and magnesium isnglyeyrrhizinate(MI). Methods 80 chronic hepati-tis B patients based on the conventional treatment were randomly divided into D1 group(40 patients) and MI group(40 pa-tients). The two groups were used with DI and MI injection for 30 days respaetively and then,the levels of liver function and serum hepatic fibrosis(HA, LN, Ⅳ -C) were detected and compared before and after treatment. Results Treatment by DI and MI could both improve liver function significantly, the effect of Ml group was better than DI group(P < 0.05). Moreover, in improving serum hepatic fibrosis, the effect of DI group was better than MI group (P < 0.05). Conclusions The efficacy of the improvement to hepatic fibrosis DI is better than MI, while in improvement of liver function MI is superior to DI.     

新医改形势下传染病医院的发展与出路

当前,由于多种客观原因,传染病医院生存与发展陷入困境,通过对传染病医院的运行情况分析,结合新医改,探讨传染病医院的发展与出路。     

探索中小城市专科医院发展新模式

(一 )近年来 ,我国城市医院数量逐步增加 ,规模也不断扩大 ,现有的卫生资源供给总量已基本能够满足当前卫生服务需求 ,有的城市已是供大于求 ,一部分卫生机构的资源利用率不高。与此同时 ,在专科医院建设上却没有受到应有的重视 ,发展相对滞后 ,多数专科医院仍然是骨干少、设备差、水平低、发展慢。专科医院特点在于“专” ,它可以按各种需要和专科发展的要求进行分工 ,为临床科研提供丰富的第一手资料 ,为专科技术人员创造深造条件 ,这些都是综合医院难以实现的。专科医院虽然有它的优势 ,但也有其不足之处 :一是医疗技术拓展受到影响。专…     

丹参注射液与异甘草酸镁抗肝纤维化的临床对比研究

目的 观察慢性乙型肝炎患者应用丹参注射液和异甘草酸镁治疗后肝功能和肝纤维化指标的改善情况.方法 将80例慢性乙型肝炎患者,随机分为丹参组40例,异甘草酸镁组40例,在常规保肝治疗基础上,两组分别加用丹参注射液和异甘草酸镁注射液治疗,疗程均为30 d.观察两组患者治疗前、后的肝功能和肝纤维化指标[血清透明质酸酶(HA)、层黏连蛋白(LN)、Ⅳ型胶原(Ⅳ-C)]的变化.结果 治疗后丹参注射液和异甘草酸镁均可明显改善慢性乙型肝炎患者的肝功能,异甘草酸镁组较丹参组为优(P<0.05).丹参组肝纤维化指标较治疗前有下降(P<0.05);异甘草酸镁组肝纤维化指标与治疗前比较差异无统计学意义(P>0.05);两组治疗后的肝纤维化指标比较,差异有统计学意义(P<0.05).结论 丹参注射液改善肝纤维化的疗效优于异甘草酸镁,而异甘草酸镁改善肝功能的疗效优于丹参注射液.     

TME联合125I粒子植入治疗中下段直肠癌

目的探讨全直肠系膜切除（TME）联合^125I粒子术中植入治疗进展期中下段直肠癌的效果。方法67例中下段直肠癌TME手术根治患者（均为Dukes’B、C期），分成3组：①组：TME手术根治加化疗组24例；②组：TME手术根治加放疗组18例；③组：TME手术根治联合^125I粒子植入组19例。跟踪随访2年内复发率；同时比较②与③组并发症的发生情况。结果3组1．5年内复发率分别为46％、11％和5％；②、⑧组复发率低于①组（x^2=4．291、6．771，P〈0．05），③组复发率与②组相比差异无显著性；但⑧组并发症的发生率（10％）比②组（44％）明显降低（确切概率计算法，P=0．029）。结论TME联合^125II粒子术中植入有助于预防直肠癌术后复发，且并发症的发生率低。     

丹参注射液与异甘草酸镁抗肝纤维化的临床对比研究

Objective To observe the change of liver function and liver fibrosis indexes of the chronic hepatitis B patients that were treated by Danshen injection(DI) and magnesium isnglyeyrrhizinate(MI). Methods 80 chronic hepati-tis B patients based on the conventional treatment were randomly divided into D1 group(40 patients) and MI group(40 pa-tients). The two groups were used with DI and MI injection for 30 days respaetively and then,the levels of liver function and serum hepatic fibrosis(HA, LN, Ⅳ -C) were detected and compared before and after treatment. Results Treatment by DI and MI could both improve liver function significantly, the effect of Ml group was better than DI group(P < 0.05). Moreover, in improving serum hepatic fibrosis, the effect of DI group was better than MI group (P < 0.05). Conclusions The efficacy of the improvement to hepatic fibrosis DI is better than MI, while in improvement of liver function MI is superior to DI.     

丹参注射液与异甘草酸镁抗肝纤维化的临床对比研究

Objective To observe the change of liver function and liver fibrosis indexes of the chronic hepatitis B patients that were treated by Danshen injection(DI) and magnesium isnglyeyrrhizinate(MI). Methods 80 chronic hepati-tis B patients based on the conventional treatment were randomly divided into D1 group(40 patients) and MI group(40 pa-tients). The two groups were used with DI and MI injection for 30 days respaetively and then,the levels of liver function and serum hepatic fibrosis(HA, LN, Ⅳ -C) were detected and compared before and after treatment. Results Treatment by DI and MI could both improve liver function significantly, the effect of Ml group was better than DI group(P < 0.05). Moreover, in improving serum hepatic fibrosis, the effect of DI group was better than MI group (P < 0.05). Conclusions The efficacy of the improvement to hepatic fibrosis DI is better than MI, while in improvement of liver function MI is superior to DI.     

探索中小城市专科医院建设发展新模式

近年来,随着医疗卫生事业的迅速发展,我国城市医院数量逐步增加,规模也不断增大,现有的卫生资源供给总量已基本能够满足当前经济水平的卫生服务需要及需求,有的城市已是供大于求,一部分卫生机构的资源利用率不高.与此同时,在专科医院建设上却没有受到应有的重视,发展速度相对滞后,多数专科医院仍然是骨干少、设备差、水平低、发展慢.     

医院专学科建设及学科带头人培养的实践探讨

随着我国医药卫生体制改革的深化．公立医院应注重内涵建设．全面提升服务能力。而做精做细做强特色专科,成为打造医院核心竞争力、提高医院品牌效应的关键。作为一所以传染病诊疗为特色的基层医院．我院以提升专科影响力为目标．着力于学科带头人队伍建没,从而带动学科的快速发展．     

血必净注射液对重症颅脑外伤患者凝血功能的影响

重症颅脑外伤是临床的常见急危重症,病死率很高,病情复杂多变,治疗有相当的难度,合并凝血功能障碍的发生率可高达70%[1].近10年来,影像学的飞速发展对颅脑外伤的救治起到了很大的作用,但仍然存在局限性.如有的患者伤后影像学改变轻微但后果严重.有些患者CT检查结果阴性却发生了迟发性脑内血肿.有些患者手术清除了颅内血肿又在远隔部位再次出现血肿.因此作者探索通过对脑外伤患者凝血机制的干预,提高其救治成功率[2].