玻璃体切除术治疗视网膜静脉阻塞所致的玻璃体出血

报告应闭合式玻璃体切除术治疗７例（７眼）因视网膜静脉阻塞所致的玻璃体出血。所有病人术后眼底清晰可见，视力明显提高。术后４例出现再出血，经药物治疗后出血吸收，加用氩离子激光视网膜光凝，无再出血。随访３至１８个月所有病人无新生血管性青光眼及牵引性视网膜脱离出现。认为玻璃体切除术不但能使屈光间质恢复透明，视力提高，预防牵引性视网膜脱离，而且为明确诊断和进一步激光治疗提供条件。     

异体脱细胞真皮治疗增生性瘢痕患者的护理

增生性瘢痕通常发生于深Ⅱ度烧伤和Ⅲ度烧伤薄皮片或邮票皮片植皮术后、感染创面和化学烧伤的创面,易造成患者关节畸形、五官移位等,严重影响外观及功能,使患者痛苦不堪.为矫正畸形,需切痕植皮或皮瓣修复,但易造成瘢痕转移[1].     

白内障超声乳化术中后囊破裂时残留晶体核的处理方法

目的：探讨白内障超声乳化术中后囊破裂时残留晶体核的处理方法。方法：回顾性地研究１８例（１８眼）超声乳化术中后囊穿时残留晶体核的处理结果。介绍低流量、低灌注、连续超声乳化法;注入高弹性粘弹性剂法;无灌注前段玻璃体切除（“干切”）等三种防止晶体核下沉的方法。随访１２～２４个月,平均１８．２月。结果：除１例特殊患者外,均未发生核下沉,且均一期植入后房人工晶体。随访时视力达到０．５者有１５眼（８３．３％）     

原发性先天性青光眼患者术后生活质量的评价

Objective To evaluate the 23-item scale of Quality of Life (QOL) for patients with primary congenital glaucoma (PCG). Methods It was a cross-sectional study. The QOL scale specific for patients with PCG was firstly evaluated on 51 patients with PCG following antiglaucomat surgery at last follow-up visit (7.80 years±2.93 years with a median at 7 years) and 50 participants with normal visual acuity (VA) as control. All participants were aged 5-20 years old. The QOL of PCG was evaluated with type of disease, severity, surgical outcome, postoperative VA, age, gender and personality by using single-factor correlation analysis and multiple-factor stepwise regression analysis. Results The PCG-QOL scale achieved good reliability, validity and responsibility for PCG and 23-item were all qualified for QOL evaluation of PCG. The total scores of QOL in patients with PCG were significantly lower than those of normal individuals (PCG 60.22±10.02,normal individuals 71.41±10.11;t=5.682, P=0.000). Single-factor correlation analysis showed that the total scores of QOL were associated significantly with the severity of glaucoma (F=24.026, P=0.000), surgical outcome (t=2.638, P=0.009) and postoperative VA (F=11.248, P=0.000) ; The visual function scores were associated significantly with the severity (F=12.677, P=0. 000) and postoperative VA (F=10.369, P=0.000) ; The self-care ability scores were associated significantly with the severity (F=11.064, P=0.000) and surgical outcome (t=2.297, P=0.042) ; The social and mental scores were all correlated significantly with the severity (F=6.869, P=0.020; F=5.721, P=0.019) and personality (t=4.352, P=0.009 ; t=2.297, P=0.042). Multiple-factor stepwise regression analysis showed that there were significant correlations between total scores and the severity (β=-6.985, P=0.001 ), postoperative VA (β=-4.978, P=0.003 ) and personality (β=-5.201, P=0.020). Conclusions The PCG-QOL scale could be used for evaluating the QOL of PCG patients aged 5-20 years. The main factors that influence on the QOL of patients with PCG are severity of the disease, postoperative VA and personality. Preventing progression of glaucoma, improving VA and giving right psychological guidance may improve the QOL of patients with PCG.     

原发性先天性青光眼患者术后生活质量的评价

Objective To evaluate the 23-item scale of Quality of Life (QOL) for patients with primary congenital glaucoma (PCG). Methods It was a cross-sectional study. The QOL scale specific for patients with PCG was firstly evaluated on 51 patients with PCG following antiglaucomat surgery at last follow-up visit (7.80 years±2.93 years with a median at 7 years) and 50 participants with normal visual acuity (VA) as control. All participants were aged 5-20 years old. The QOL of PCG was evaluated with type of disease, severity, surgical outcome, postoperative VA, age, gender and personality by using single-factor correlation analysis and multiple-factor stepwise regression analysis. Results The PCG-QOL scale achieved good reliability, validity and responsibility for PCG and 23-item were all qualified for QOL evaluation of PCG. The total scores of QOL in patients with PCG were significantly lower than those of normal individuals (PCG 60.22±10.02,normal individuals 71.41±10.11;t=5.682, P=0.000). Single-factor correlation analysis showed that the total scores of QOL were associated significantly with the severity of glaucoma (F=24.026, P=0.000), surgical outcome (t=2.638, P=0.009) and postoperative VA (F=11.248, P=0.000) ; The visual function scores were associated significantly with the severity (F=12.677, P=0. 000) and postoperative VA (F=10.369, P=0.000) ; The self-care ability scores were associated significantly with the severity (F=11.064, P=0.000) and surgical outcome (t=2.297, P=0.042) ; The social and mental scores were all correlated significantly with the severity (F=6.869, P=0.020; F=5.721, P=0.019) and personality (t=4.352, P=0.009 ; t=2.297, P=0.042). Multiple-factor stepwise regression analysis showed that there were significant correlations between total scores and the severity (β=-6.985, P=0.001 ), postoperative VA (β=-4.978, P=0.003 ) and personality (β=-5.201, P=0.020). Conclusions The PCG-QOL scale could be used for evaluating the QOL of PCG patients aged 5-20 years. The main factors that influence on the QOL of patients with PCG are severity of the disease, postoperative VA and personality. Preventing progression of glaucoma, improving VA and giving right psychological guidance may improve the QOL of patients with PCG.     

颞侧透明角膜隧道切口的二期人工晶体植入术

探讨经颞侧透明角膜隧道切口的二期人工晶体植入术的方法及优点。方法 :用钻石刀在颞侧角膜周边血管弓中央的透明角膜上 ,做一深 0 3mm ,长 3 2mm ,宽 1 75mm的角膜隧道切口 ,对 5 0例5 3只眼的无晶体眼行二期人工晶体植入术 ,植入可折叠人工晶体。随访 6～ 12个月 ,平均 8 4个月 ,观察术后视力、角膜曲率、人工晶体位置及术中、术后并发症。结果 :手术时间为 15～ 40分钟 ,平均 2 6分钟。术后第一天矫正视力≥ 0 5者 2 0只眼 (占 37 73 % ) ;术后 1周和 3个月矫正视力≥ 1 0者分别为 2 6眼 (占 49 0 5 % )和 35眼 (占 6 6 0 3 % )。术后一天和三个月平均散光为 0 6 1± 0 42D和 0 5 1± 0 37D与术前比较无统计学差异。手术并发症主要为术中后囊破裂 ( 5眼 ) ,术后晶体偏心 ( 2眼 )和黄斑囊样水肿 ( 3眼 )。结论 :经颞侧透明角膜隧道切口的二期折叠式人工晶体植入术具有手术时间短、并发症少、操作简单、视力恢复快等优点 ,适应于绝大部分的无晶体眼患者。     

超声乳化术后急性化脓性眼内炎的2例报告

【目的】探讨2例白内障超声乳化术后急性化脓性眼内炎的临床特点及防治方法。【方法】回顾中山大学中山眼科中心自1999年1月至2003年6月9630例施行白内障超声乳化吸除术的住院患者资料,分析术中去甲万古霉素的使用对急性化脓性眼内炎的预防作用,眼内炎患者的临床表现及治疗经过。【结果】术后发生眼内炎者共2例,发生率为0.021％;该2例患者通过前房冲洗、经睫状体平坦部后段玻璃体切除术及玻璃体腔内注药治疗,眼内炎得到控制,术后均保存了眼球及视力。【结论】超声乳化白内障吸除术后急性化脓性眼内炎的发生率很低;对于发生眼内炎的患者,及时的前房冲洗、后段玻璃体切除术联合玻璃体腔内注药可挽救眼球,并保存一定视力。     

Healon 5的临床应用研究

目的 观察Healon 5在超声乳化白内障摘出联合人工晶状体植入术中的应用效果。 方法 在90眼超声乳化白内障摘出联合人工晶状体植入术中应用不同的黏弹性物质。一组30眼为实验组,应用Healon5 ,另两组各30眼为对照组,分别应用Healon GV和爱维。手术采朋颞侧透明角膜切口的原位超声乳化术,囊袋内植入折叠人工晶状体。采用不同方式清除前房内黏弹剂。术中观察黏弹剂的黏弹性、弥散性及抽吸时间,手术前后观察患眼的视力、眼压、角膜和前房反应。结果 Healon 5、Healon GV、爱维的抽吸时间分别为(单位:s)47.42±1 3.09、16.50±5.45、15 83±7.40,实验组与对照组比较差异有显著性(P=0.00)。三组患者手术前后眼压变化差异无显著性:(P>0.05)。术后角膜与前房反应从轻到重依次为Healon 5组相似文献   

眼用维甲酸缓释胶囊的制备和体外药物释放速度的测定

一定浓度的维甲酸可有效抑制细胞增殖 ,诱导细胞分化和生理凋亡 ,有望在后发性白内障的预防研究中发挥作用[1,2 ] 。我们自 1999年 7月开始研制一种可长期恒定释放一定药物浓度的新型眼用全反式维甲酸 (ａｌｌ ｔｒａｎｓｒｅｔｉｎｏｉｃａｃｉｄ ,ＲＡ)缓释胶囊 ,现将其制备方法和体外药物释放特点报告如下。一、材料和方法1 ＲＡ缓释胶囊的制备方法 :聚己内酯 (ｐｏｌｙｃａｐｒｏｌａｃｔｏｎｅ,ＰＣＬ)管由中国医学科学院生物医学工程研究所提供。ＰＣＬ管壁的厚度为 0 2ｍｍ ,内直径为 1 7ｍｍ ,外直径为 2 1ｍｍ ;管壁上微孔密度为…     

眼用维甲酸缓释胶囊的制备和体外药物释放速率的测定

一定浓度的维甲酸可有效抑制细胞增殖,诱导细胞分化和生理凋亡,有望在后发性白内障的预防研究中发挥作用[1,2].我们自1999年7月开始研制一种可长期恒定释放一定药物浓度的新型眼用全反式维甲酸(all-trans retinoic acid, RA)缓释胶囊,现将其制备方法和体外药物释放特点报告如下.