Do Neuroimaging Results Impact Prognosis of Epilepsy Surgery? A Meta-analysis

The neuroimaging results of drug-resistant epilepsy patients play an important role in the surgery decision and prognosis. The aim of this study was to evaluate the impact of these results on the efficacy of epilepay surgery, and then to explore surgical benefit for epilepsy patients with negative magnetic resonance (MR) images. Twenty-four subgroups describing the outcomes of 1475 epilepsy patients with positive-neuroimaging results and 696 patients with negative-neuroimaging results were involved in the meta-analysis. Overall, the odds of postoperational seizure-free rate were 2.03 times higher in magnetic resonance imaging-positive (MRI-positive) patients than in MRI-negative patients [odds ratio (OR)=2.03,95% CI (1.67,2.47),P<0.00001]. For patients with temporal lobe epilepsy (TLE), the odds were 1.76 times higher in those with MRI-positive results than in those with MRI-negative results [OR=1.76,95% CI (1.34,2.32), P<0.0001]. For patients with extra-temporal lobe epilepsy (extra-TLE), the odds were 2.88 times higher in MRI-positive patients than in MRI-negative patients [OR=2.88,95% CI(1.53,5.43),P=0.001]. It was concluded that the seizure-free rate of MRI-positive patients after surgery was higher than that of MRI-negative patients. For patients with negative results, an appropriate surgery should be concerned for TLE.     

武汉市部分初中学生性态度调查

目的:了解初中生性态度状况,为进行适宜的初中生性健康教育提供依据.方法:采用分层整群抽样方法,对武汉市某中学212名初一、二学生进行自编的初中生性知识性态度问卷调查.结果:初二学生中有13.71%赞同初中生谈恋爱,态度较初一学生开放;5.36%男生赞同初中生发生性行为,态度较女生开放.对于初中生性行为可能导致的后果,认识不够正确和全面.结论:初中生的性态度呈现不均衡的现象,应重视初中生性健康,为他们提供科学、全面的性健康教育.