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Streibert Fridolin Bernhardt Claudia Simon Philipp Hilbert-Carius Peter Wrigge Hermann 《Der Anaesthesist》2023,72(1):57-62
Die Anaesthesiologie - Die Anlage einer Magensonde im OP oder auf einer Intensivstation (ITS) stellt eine alltäglich durchgeführte Prozedur dar. Obwohl die Sonde häufig durch... 相似文献
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Wrigge H Zinserling J Hering R Schwalfenberg N Stüber F von Spiegel T Schroeder S Hedenstierna G Putensen C 《Anesthesiology》2001,95(2):382-389
BACKGROUND: Spontaneous breaths during airway pressure release ventilation (APRV) have to overcome the resistance of the artificial airway. Automatic tube compensation provides ventilatory assistance by increasing airway pressure during inspiration and lowering airway pressure during expiration, thereby compensating for resistance of the artificial airway. The authors studied if APRV with automatic tube compensation reduces the inspiratory effort without compromising cardiovascular function, end-expiratory lung volume, and gas exchange in patients with acute lung injury. METHODS: Fourteen patients with acute lung injury were breathing spontaneously during APRV with or without automatic tube compensation in random order. Airway pressure, esophageal and abdominal pressure, and gas flow were continuously measured, and tracheal pressure was estimated. Transdiaphragmatic pressure time product was calculated. End-expiratory lung volume was determined by nitrogen washout. The validity of the tracheal pressure calculation was investigated in seven healthy ventilated pigs. RESULTS: Automatic tube compensation during APRV increased airway pressure amplitude from 7.7+/-1.9 to 11.3+/-3.1 cm H2O (mean +/- SD; P < 0.05) while decreasing trans-diaphragmatic pressure time product from 45+/-27 to 27+/-15 cm H2O x s(-1) x min(-1) (P < 0.05), whereas tracheal pressure amplitude remained essentially unchanged (10.3+/-3.5 vs. 10.1+/-3.5 cm H2O). Minute ventilation increased from 10.4+/-1.6 to 11.4+/-1.5 l/min (P < 0.001), decreasing arterial carbon dioxide tension from 52+/-9 to 47+/-6 mmHg (P < 0.05) without affecting arterial blood oxygenation or cardiovascular function. End-expiratory lung volume increased from 2,806+/-991 to 3,009+/-994 ml (P < 0.05). Analysis of tracheal pressure-time curves indicated nonideal regulation of the dynamic pressure support during automatic tube compensation as provided by a standard ventilator. CONCLUSION: In the studied patients with acute lung injury, automatic tube compensation markedly unloaded the inspiratory muscles and increased alveolar ventilation without compromising cardiorespiratory function and end-expiratory lung volume. 相似文献
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Schachtrupp A Wrigge H Busch T Buhre W Weyland A 《European journal of anaesthesiology》2005,22(3):165-170
BACKGROUND AND OBJECTIVE: The effects of intra-aortic balloon pumping (IABP) on cerebral perfusion are still a matter of debate. End-diastolic reversal of blood flow in cerebral arteries has been observed in a small number of patients. We prospectively investigated the incidence and the amount of transient cerebral artery blood flow reversal during balloon pumping in patients recovering from cardiac surgery. METHODS: In 23 patients receiving IABP support, blood flow velocities in the right middle cerebral artery were assessed by transcranial Doppler-sonography. Additionally, systemic haemodynamics were monitored. In each patient, measurements were performed at three different pump settings: without support, assist ratio 1 : 1 and assist ratio 1 : 2. RESULTS: In 8 of 23 patients, balloon pumping caused a transient diastolic reversal of blood flow in the middle cerebral artery during balloon deflation. Antegrade mean flow velocity in the middle cerebral artery significantly increased from 57 +/- 27 to 61 +/- 26 (assist ratio 1 : 1) and 61 +/- 29 cm s(-1) (assist ratio 1 : 2) (P < 0.05). Taking transient blood flow reversal into account, net mean flow velocity did not increase with balloon pump support. Systemic haemodynamic parameters remained unchanged. CONCLUSION: Left ventricular support with IABP significantly changed flow patterns in basal cerebral arteries of our patients. In 35% of patients, support resulted in a transient reversal of intracranial blood flow which counterbalanced a slight increase in mean antegrade flow. 相似文献
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Severe accidental hypothermia: rewarming strategy using a veno-venous bypass system and a convective air warmer 总被引:1,自引:0,他引:1
A. Bräuer H. Wrigge J. Kersten J. Rathgeber W. Weyland H. Burchardi 《Intensive care medicine》1999,25(5):520-523
Objective: To study a rewarming strategy for patients with severe accidental hypothermia using a simple veno-venous bypass in combination
with a convective air warmer. Setting: Eighteen beds in a university hospital intensive care unit. Patients: Four adults admitted with a core temperature less than 30 °C. Hypothermia was caused by alcoholic intoxication in three patients
and by drug overdose in one patient. Measurements and main results: All patients were rewarmed by a veno-venous bypass and in three cases a convective air warmer was also used. At a bypass
flow rate of 100–300 ml/min the mean increase in core temperature was 1.15 °C/h (Range: 1.1–1.2 °C/h). One patient died 2
days after rewarming as a consequence of a reactivated pancreatitis. The other three patients survived without neurological
sequelae. Conclusion: This rewarming technique seems safe and effective and allowed the controlled rewarming of our patients who suffered from
severe accidental hypothermia
Received: 15 September 1998 Final revision received: 4 January 1999 Accepted: 11 February 1999 相似文献
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