全文获取类型
收费全文 | 2185篇 |
免费 | 88篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 56篇 |
儿科学 | 60篇 |
妇产科学 | 25篇 |
基础医学 | 470篇 |
口腔科学 | 16篇 |
临床医学 | 117篇 |
内科学 | 516篇 |
皮肤病学 | 8篇 |
神经病学 | 170篇 |
特种医学 | 49篇 |
外科学 | 341篇 |
综合类 | 4篇 |
预防医学 | 65篇 |
眼科学 | 22篇 |
药学 | 91篇 |
中国医学 | 2篇 |
肿瘤学 | 264篇 |
出版年
2023年 | 11篇 |
2022年 | 17篇 |
2021年 | 25篇 |
2020年 | 11篇 |
2019年 | 14篇 |
2018年 | 30篇 |
2017年 | 26篇 |
2016年 | 26篇 |
2015年 | 32篇 |
2014年 | 32篇 |
2013年 | 48篇 |
2012年 | 74篇 |
2011年 | 104篇 |
2010年 | 54篇 |
2009年 | 52篇 |
2008年 | 100篇 |
2007年 | 131篇 |
2006年 | 134篇 |
2005年 | 130篇 |
2004年 | 142篇 |
2003年 | 153篇 |
2002年 | 203篇 |
2001年 | 36篇 |
2000年 | 24篇 |
1999年 | 46篇 |
1998年 | 58篇 |
1997年 | 51篇 |
1996年 | 38篇 |
1995年 | 45篇 |
1994年 | 35篇 |
1993年 | 40篇 |
1992年 | 27篇 |
1991年 | 36篇 |
1990年 | 21篇 |
1989年 | 23篇 |
1988年 | 18篇 |
1987年 | 20篇 |
1986年 | 16篇 |
1985年 | 8篇 |
1984年 | 11篇 |
1983年 | 10篇 |
1982年 | 14篇 |
1981年 | 12篇 |
1978年 | 13篇 |
1977年 | 8篇 |
1976年 | 12篇 |
1975年 | 14篇 |
1974年 | 10篇 |
1973年 | 11篇 |
1968年 | 10篇 |
排序方式: 共有2276条查询结果,搜索用时 15 毫秒
1.
2.
Shinji Naganawa Rintaro Ito Hisashi Kawai Toshiaki Taoka Tadao Yoshida Michihiko Sone 《Magnetic resonance in medical sciences》2020,19(4):375
Purpose:It has been reported previously that intravenously administered gadolinium-based contrast agent (GBCA) leaks into the subarachnoid space around the cortical veins at 4 h after injection in all old people over 37 years, but not in younger people up to 37 years of age in 3D-real IR images. The purpose of this study was to investigate whether there was a strict threshold of 37 years of age for the leakage of the GBCA into the subarachnoid space.Methods:The subjects included 190 patients, that were scanned for 3D-real IR images at 4 hours after intravenous injection of GBCA as a diagnostic test for endolymphatic hydrops. The patient’s age ranged from 14 to 81 years. Two experienced neuroradiologists evaluated the images to determine whether the GBCA leakage around the cortical veins was positive or negative. Any discrepancies between the two observers were discussed and a consensus was obtained.A Mann–Whitney U test and receiver operating characteristic (ROC) curve analysis were used to compare the positive and the negative group and to set the age cut-off value for the prediction of GBCA leakage.Results:The GBCA leakage around the cortical veins was negative in 35 patients and positive in 155 patients. The average age was 33 ± 11 years in the negative group, and 55 ± 12 years in the positive group (P < 0.01). In the ROC analysis for the age and leakage of the GBCA, an area under the curve was 0.905 and the cut-off age was 37.317 years (sensitivity of 0.942 and specificity of 0.771).Conclusion:Intravenously administered GBCA leaks into the subarachnoid space around the cortical veins in most patients over 37 years of age. However, it should be noted that it can be found occasionally in patients under 37 years of age. 相似文献
3.
4.
The case of a 75-year-old man with three synchronous carcinomas of the lung (large cell carcinoma, adenocarcinoma, and small cell carcinoma) is reported. This is the eighth well-documented case report in the literature; however, our case is the first to be reported with the newly described histological combination. 相似文献
5.
从1991年开始,口服的碳吸附剂AST-120在日本被用于治疗慢性肾脏病(CKD)患者,但是在其他国家却不常用。在CKD的动物模型中,AST-120可清除尿毒症毒素,减轻氧化应激;在组织学水平观察到它可明显延缓肾小球硬化、肾间质纤维化、近端肾小管肥大的进展。在部分肾切除的大鼠模型中,AST-120显示出对其肾脏的保护作用超过了低蛋白饮食和降压药物。在CKD的患者中,AST-120也显示可延缓肾小球滤过率(GFR)及血肌酐浓度倒数下降的作用。 相似文献
6.
Nephron Sparing Surgery for De Novo Renal Cell Carcinoma in an Allograft Kidney: A Case Report 总被引:1,自引:0,他引:1
Kyun II Park Hitoshi Inoue Choi Jan Kim Tadao Tomoyoshi 《International journal of urology》1997,4(6):611-614
De novo renal cell carcinoma in a renal allograft is rare and has special implications in renal transplant recipients. We describe a patient with a renal allograft who developed a de novo renal cell carcinoma in the functioning renal allograft 258 months after transplantation. The patient underwent enucleation of the tumor because preoperative MRI showed it was well-encapsulated. A DNA banding study showed that the tumor originated from the donor. Indications for conservative renal surgery in renal cell carcinoma have been increasing. Accordingly, 1 option in the treatment of de novo renal cell carcinoma in a functioning renal allograft is enucleation as a method of nephron sparing surgery. 相似文献
7.
Palmar advancement flap with V-Y closure for thumb tip injuries 总被引:1,自引:0,他引:1
Hwang-hyun Bang MD Tadao Kojima MD Hiroyuki Hayashi MD 《The Journal of hand surgery》1992,17(5):933-934
The palmar advancement flap with V-Y closure was used in two patients with thumb tip injuries. This technique allows more distal advancement of the flap than does a conventional palmar advancement flap and does not require skin graft coverage. 相似文献
8.
A Kitami K Suzuki G Hori T Akizawa M Narushima E Noguchi Y Iida F Sagawa 《Nihon Kyōbu Shikkan Gakkai zasshi》1991,29(11):1505-1508
A 66-year-old woman visited our hospital for further investigation of a coin-shaped lesion in the right lower lung field. After admission, CT-scan revealed an anterior mediastinal tumor. Thymoma and lung metastasis from thymoma were suspected. At thoracotomy, an invasive thymoma involving the left phrenic nerve, the left upper lobe, and the pericardium was found, and the diagnosis of lung metastasis was made. Postoperative pathological findings showed a predominantly lymphocytic thymoma with round and oval-shaped epithelial cells, and the metastatic lung lesion revealed the same findings. Postoperative radiotherapy (4000 rads) and chemotherapy with a combination of CDDP, VDS, and CPA were administered. The metastasis of thymoma is not rare, but most often it is found after operation. In this case the diagnosis of metastatic thymoma was made pre-operatively from a solitary lung lesion. 相似文献
9.
Mariko Hosono H. Kobayashi Ryota Fujimoto Kazushige Tsutsui Yoshihiko Kotoura Tadao Tsuboyama Hikaru Hayashi Takashi Nakamura Junji Konishi 《Skeletal radiology》1997,26(9):525-528
Objective. To clarify the MRI features of parasymphyseal insufficiency fractures of the os pubis. Design and patients. MRI was performed in four postmenopausal women with parasymphyseal insufficiency fractures. The diagnosis was confirmed with
plain films in every patient. T1-weighted and T2-weighted images were obtained in four patients using a 1.5-T unit. Postcontrast
T1-weighted imaging was also done in three patients. Results and conclusions. MRI of pubic parasymphyseal insufficiency fracture characteristically demonstrates a hyperintense mass lesion with a hypointense
rim on T2-weighted imaging, showing peripheral and septal enhancement after contrast administration. It is important to have
this entity in mind in patients with osteoporosis, especially in patients with a history of pelvic irradiation for malignant
disease, so as not to misinterpret it as a chondroid tumor or bone metastasis. 相似文献
10.
Takao Kamezaki Kiyoyuki Yanaka Keishi Fujita Kazuhiro Nakamura Yasushi Nagatomo Tadao Nose 《Journal of clinical neuroscience》2004,11(3):311-313
Subdural hygroma is a frequent delayed complication of head trauma. Most hygromas are clinically 'silent' and a few cases have shown slow deterioration in the chronic stage. We report a case of subdural hygroma showing unique radiological findings and rapid deterioration. A 74-years-old female presented with a mild headache and consciousness disturbance after head injury. Computed tomography showed a midline shift as a result of two components piling up in the subdural space; the outer components showed low density, the inner components high density. Magnetic resonance imaging demonstrated that these two subdural components were subdural hygroma and subarachnoid hematoma. Simple burr hole irrigation, rather than large craniotomy, was thought to be more appropriate treatment to reduce the mass effect. Simple burr hole irrigation was performed to remove the subdural hygroma and the patient showed an excellent recovery. Careful examination of the radiological findings prevented an unnecessary procedure in this case. A possible mechanism of this phenomenon is discussed. 相似文献