全文获取类型
收费全文 | 29325篇 |
免费 | 2063篇 |
国内免费 | 119篇 |
专业分类
耳鼻咽喉 | 348篇 |
儿科学 | 622篇 |
妇产科学 | 587篇 |
基础医学 | 4381篇 |
口腔科学 | 415篇 |
临床医学 | 2662篇 |
内科学 | 6791篇 |
皮肤病学 | 506篇 |
神经病学 | 3108篇 |
特种医学 | 1117篇 |
外国民族医学 | 3篇 |
外科学 | 4857篇 |
综合类 | 161篇 |
一般理论 | 7篇 |
预防医学 | 1585篇 |
眼科学 | 446篇 |
药学 | 2120篇 |
中国医学 | 100篇 |
肿瘤学 | 1691篇 |
出版年
2023年 | 102篇 |
2022年 | 175篇 |
2021年 | 462篇 |
2020年 | 289篇 |
2019年 | 509篇 |
2018年 | 622篇 |
2017年 | 465篇 |
2016年 | 526篇 |
2015年 | 672篇 |
2014年 | 870篇 |
2013年 | 1182篇 |
2012年 | 1795篇 |
2011年 | 1851篇 |
2010年 | 1178篇 |
2009年 | 1044篇 |
2008年 | 1755篇 |
2007年 | 1853篇 |
2006年 | 1740篇 |
2005年 | 1810篇 |
2004年 | 1748篇 |
2003年 | 1738篇 |
2002年 | 1656篇 |
2001年 | 536篇 |
2000年 | 477篇 |
1999年 | 544篇 |
1998年 | 436篇 |
1997年 | 367篇 |
1996年 | 316篇 |
1995年 | 327篇 |
1994年 | 263篇 |
1993年 | 263篇 |
1992年 | 369篇 |
1991年 | 318篇 |
1990年 | 265篇 |
1989年 | 293篇 |
1988年 | 242篇 |
1987年 | 247篇 |
1986年 | 246篇 |
1985年 | 202篇 |
1984年 | 177篇 |
1983年 | 170篇 |
1982年 | 144篇 |
1981年 | 122篇 |
1980年 | 112篇 |
1979年 | 123篇 |
1978年 | 73篇 |
1977年 | 102篇 |
1975年 | 80篇 |
1974年 | 65篇 |
1973年 | 90篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Schneider Ralph Dettmer Marius Peters Nora Lamdark Tenzin Luedi Markus M. Adamina Michel Doll Dietrich 《European Surgery》2022,54(2):117-125
European Surgery - Treatment of pilonidal sinus disease (PSD) requires a tailored approach. A national guideline was published in 2014. The current status of surgical PSD therapy... 相似文献
2.
Despite common experiences of identity damage, decline, and deterioration, many brain injury survivors succeed in reconstructing robust identities in the wake of injury. Yet, while this accomplishment greatly benefits survivors’ quality of life, little is known about how positive identity work might be facilitated or enhanced in therapeutic institutions. Drawing on data from a women’s self-help group, we argue that an egalitarian, reflective, strength-focused, and gender-segregated environment can provide female ABI (acquired brain injury) survivors with a fertile scene for identity enhancement and offer unique opportunities for collective identity development. Sociolinguistic interactional analysis revealed four types of positive identity work undertaken within the group: constructing competent selves; tempering the threat of loss and impairment; resisting infantilisation and delegitimisation; and asserting a collective gender identity. This identity work was facilitated by specific programme attributes and activities and contributed to the global project of decentring disability and destigmatising impairments and losses. We call for increased attention to identity issues in brain injury rehabilitation and argue that gender-segregated programming can provide a unique space for female survivors to construct empowering individual and collective identities after injury. 相似文献
3.
4.
5.
6.
B. Midouni E. Mehiri A. Ghariani H. Draoui L. Essalah I. Bouzouita D. Raoult L. Slim-Saidi P.E. Fournier 《International journal of antimicrobial agents》2019,53(1):63-69
Objectives
This study aimed to explore the genetic diversity of Streptococcus pneumoniae isolates in a Tunisian pneumology hospital.Methods
A total of 141 S. pneumoniae strains isolated between 2009–2016 in the microbiology laboratory at A. Mami Hospital of Pneumology were investigated. Antimicrobial susceptibility testing was performed the disk diffusion method. MICs of penicillin G, amoxicillin and cefotaxime were determined by Etest. Serotyping was inferred from the results of multiplex PCR targeting 40 serotypes. Sequence types (STs) were determined by multilocus sequence typing (MLST).Results
Among the 141 S. pneumoniae isolates, 98 (69.5%) were resistant to erythromycin. Evaluation of β-lactam susceptibility showed that 90 strains (63.8%) were non-susceptible to penicillin, whereas 48 (34.0%) had decreased susceptibility to amoxicillin and 21 (14.9%) to cefotaxime. Twenty-five serotypes were detected, and 10 isolates were classified as non-typeable. Vaccine coverage was 56.7%, 60.3% and 75.2% for pneumococcal conjugate vaccine 7 (PCV7), PCV10 and PCV13, respectively. Overall, 73 STs were identified, including 23 described for the first time. The most frequent STs were ST179 (n?=?17), ST3772 (n?=?14), ST2918 (n?=?10) and ST4003 (n?=?5), related to serotypes 19F, 19A, 14 and 23F, respectively. Moreover, 110 strains were classified within 45 STs. Three international antimicrobial-resistant clones were found, including Denmark14-ST230 (n?=?22), Spain9V-ST156 (n?=?22) and Portugal19F-ST177 (n?=?20).Conclusion
This study emphasises the clonal and international dissemination of antimicrobial-resistant S. pneumoniae clones. Significant differences in genetic variation were documented by MLST within the various serotypes identified. 相似文献7.
Hanna Lee Mary K. Tan Andrew T. Yan Paul Angaran Paul Dorian Claudia Bucci Jean C. Gregoire Alan D. Bell Martin S. Green Peter L. Gross Allan Skanes Charles R. Kerr L. Brent Mitchell Jafna L. Cox Vidal Essebag Brett Heilbron Krishnan Ramanathan Carl Fournier Shaun G. Goodman 《The Canadian journal of cardiology》2019,35(2):160-168
Background
Physicians treating nonvalvular atrial fibrillation (AF) assess stroke and bleeding risks when deciding on anticoagulation. The agreement between empirical and physician-estimated risks is unclear. Furthermore, the association between patient and physician sex and anticoagulation decision-making is uncertain.Methods
We pooled data from 2 national primary care physician chart audit databases of patients with AF (Facilitating Review and Education to Optimize Stroke Prevention in Atrial Fibrillation and Coordinated National Network to Engage Physicians in the Care and Treatment of Patients with Atrial Fibrillation Chart Audit) with a combined 1035 physicians (133 female, 902 male) and 10,927 patients (4567 female and 6360 male).Results
Male physicians underestimated stroke risk in female patients and overestimated risk in male patients. Female physicians estimated stroke risk well in female patients but underestimated the risk in male patients. Risk of bleeding was underestimated in all. Despite differences in risk assessment by physician and patient sex, > 90% of patients received anticoagulation across all subgroups. There was modest agreement between physician estimated and calculated (ie, CHADS2 score) stroke risk: Kappa scores were 0.41 (0.35-0.47) for female physicians and 0.34 (0.32-0.36) for male physicians.Conclusions
Our study is the first to examine the association between patient and physician sex influences and stroke and bleeding risk estimation in AF. Although there were differences in agreement between physician estimated stroke risk and calculated CHADS2 scores, these differences were small and unlikely to affect clinical practice; further, despite any perceived differences in the accuracy of risk assessment by sex, most patients received anticoagulation. 相似文献8.
Renaud Snanoudj Nassim Kamar Elisabeth Cassuto Sophie Caillard Marie Metzger Pierre Merville Antoine Thierry Isabelle Jollet Philippe Grimbert Dany Anglicheau Marc Hazzan Gabriel Choukroun Bruno Hurault De Ligny Bénedicte Janbon Vincent Vuiblet Anne Devys Yann Le Meur Michel Delahousse Jean-Luc Taupin 《Kidney international》2019,95(6):1471-1485
9.
10.
New latex reagent using monoclonal antibodies to capsular polysaccharide for reliable identification of both oxacillin-susceptible and oxacillin-resistant Staphylococcus aureus. 总被引:5,自引:5,他引:0 下载免费PDF全文
J M Fournier A Bouvet D Mathieu F Nato A Boutonnier R Gerbal P Brunengo C Saulnier N Sagot B Slizewicz et al. 《Journal of clinical microbiology》1993,31(5):1342-1344
A new latex agglutination test (Pastorex Staph-Plus, Sanofi Diagnostics Pasteur), consisting of a mixture of latex particles coated with fibrinogen and immunoglobulin G for the detection of clumping factor and protein A and latex particles sensitized with monoclonal antibodies directed to Staphylococcus aureus serotype 5 and 8 capsular polysaccharides, was compared with three commercially available rapid agglutination methods for the identification of 220 isolates of S. aureus (61 oxacillin resistant) and 128 isolates of coagulase-negative staphylococci. The sensitivity for identification of S. aureus was high with the Pastorex Staph-Plus test (98.6%) compared with those of the other tests, which ranged from 91.8 to 84.5%. Test sensitivities for the identification of oxacillin-resistant S. aureus were as follows: Pastorex Staph-Plus, 95.1%; Pastorex Staph, 73.8%; Staphyslide, 72.1%; and StaphAurex, 49.2%. 相似文献