全文获取类型
收费全文 | 1094916篇 |
免费 | 70694篇 |
国内免费 | 2865篇 |
专业分类
耳鼻咽喉 | 15021篇 |
儿科学 | 34520篇 |
妇产科学 | 31271篇 |
基础医学 | 154444篇 |
口腔科学 | 30947篇 |
临床医学 | 87502篇 |
内科学 | 225775篇 |
皮肤病学 | 25089篇 |
神经病学 | 87594篇 |
特种医学 | 41263篇 |
外国民族医学 | 344篇 |
外科学 | 164700篇 |
综合类 | 20027篇 |
一般理论 | 284篇 |
预防医学 | 86372篇 |
眼科学 | 24786篇 |
药学 | 78727篇 |
中国医学 | 2544篇 |
肿瘤学 | 57265篇 |
出版年
2021年 | 9725篇 |
2019年 | 10334篇 |
2018年 | 14697篇 |
2017年 | 10728篇 |
2016年 | 11368篇 |
2015年 | 12685篇 |
2014年 | 17495篇 |
2013年 | 26677篇 |
2012年 | 37524篇 |
2011年 | 39629篇 |
2010年 | 23110篇 |
2009年 | 21232篇 |
2008年 | 36214篇 |
2007年 | 38417篇 |
2006年 | 38225篇 |
2005年 | 37424篇 |
2004年 | 35475篇 |
2003年 | 33956篇 |
2002年 | 33358篇 |
2001年 | 46557篇 |
2000年 | 48129篇 |
1999年 | 40768篇 |
1998年 | 11246篇 |
1997年 | 10053篇 |
1996年 | 9906篇 |
1995年 | 9149篇 |
1994年 | 8689篇 |
1992年 | 30665篇 |
1991年 | 29313篇 |
1990年 | 28732篇 |
1989年 | 27416篇 |
1988年 | 25479篇 |
1987年 | 24951篇 |
1986年 | 24058篇 |
1985年 | 22824篇 |
1984年 | 17059篇 |
1983年 | 14581篇 |
1982年 | 8746篇 |
1979年 | 15975篇 |
1978年 | 11149篇 |
1977年 | 9520篇 |
1976年 | 8985篇 |
1975年 | 9997篇 |
1974年 | 11954篇 |
1973年 | 11490篇 |
1972年 | 10890篇 |
1971年 | 10074篇 |
1970年 | 9702篇 |
1969年 | 9202篇 |
1968年 | 8839篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
3.
F. Fruzzetti G. Palla A. Sbrana T. Simoncini M. R. Sessa 《Gynecological endocrinology》2020,36(10):938-940
AbstractObjective: To understand the origin of extremely high gonadotropin levels in a perimenopausal woman.Methods: A 52-year-old woman with a 2?months of amenorrhea followed spontaneous menstrual cycles recovery was referred to our outpatient clinic with elevated follicle-stimulating hormone (FSH, 483 mUI/ml), luteinizing hormone (LH, 475 mUI/ml) and prolactin (PRL, 173?ng/ml). She was known to take levosulpiride. The gonadotropin levels did not fit with the clinical features.Results: A gonadotroph tumor was ruled out. Further analysis confirmed constantly high FSH, LH and PRL levels. The measurements were repeated using different analytical platforms with different results. After serial dilutions, nonlinearity was present suggesting an immunoassay interference. After post-polyethylene glycol recovery, hormone levels appeared in the normal range. Anti-goat antibodies were recognized in the serum of the patient.Conclusions: This case report shows a case of falsely abnormal high gonadotropin and PRL levels in a woman during menopause transition. In the clinical practice the evaluation of gonadotropin profile is not recommended at this age, but the abnormal levels stimulated further evaluation. An interference in the assay due to anti-goat antibodies resulted in abnormally high level of FSH and LH. A strict collaboration between clinicians and the laboratory is needed, when laboratory findings do not correspond to clinical findings. 相似文献
4.
5.
6.
7.
F. Murina R. Felice S. Di Francesco L. Nelvastellio I. Cetin 《Gynecological endocrinology》2020,36(5):431-435
AbstractThis study is a single-center, retrospective analysis of postmenopausal women presenting with dyspareunia and vulvar pain, aiming to evaluate relative effectiveness of vestibular CO2 laser therapy as a treatment. Three monthly sessions of laser were performed to each patient and thereafter a three-months follow-up was stablished. A total number of 72 patients undergoing vestibular laser treatment were recruited from patient files in the period between 2016 and 2018. Among these, 39 women also received a concomitant treatment with ospemifene (60?mg/day) during the study period. There was a statistically significant reduction of all the symptoms in both groups up to the three month follow-up. Regarding dryness and dyspareunia, the relief tent to be more prominent in the ospemifene?+?laser group at all follow-ups and remained statistically significant at three-month follow-up. Specifically, vestibular dryness was significantly lower in the ospemifene?+?laser group compared with the laser treatment group (?87% vs???34%, respectively), and the vestibular health score started declining faster in the ospemifene?+?laser group. Although, additional research is needed to understand the mechanism of action, our data shows that a combination regimen of laser and ospemifene may improve clinical effectiveness for long-term treatment of symptoms associated with the under-recognized genitourinary syndrome of menopause. 相似文献
8.
María Cabrerizo Gloria Trallero María José Pena Amaia Cilla Gregoria Megias Carmen Mu?oz-Almagro Eva Del Amo Diana Roda Ana Isabel Mensalvas Antonio Moreno-Docón Juan García-Costa Nuria Rabella Manuel Ome?aca María Pilar Romero Sara Sanbonmatsu-Gámez Mercedes Pérez-Ruiz María José Santos-Mu?oz Cristina Calvo And the study group of “Enterovirus parechovirus infections in children under ?years-old Spain” PI- 《European journal of pediatrics》2015,174(11):1511-1516
9.
J. Rodríguez-Carrio A. Martínez-Zapico I. Cabezas-Rodríguez L. Benavente Á.I. Pérez-Álvarez P. López J.B. Cannata-Andía M. Naves-Díaz A. Suárez 《Nutrition, metabolism, and cardiovascular diseases : NMCD》2019,29(2):135-143
Background and aims
Since accelerated atherosclerosis has been reported in systemic lupus erythematosus (SLE), predictive biomarkers of cardiovascular disease (CVD) are needed. Among non-traditional risk factors, bone mineral density (BMD) has been related to CVD. However, its role in SLE remains controversial. This study aims to analyze the associations of subclinical atherosclerosis with traditional and non-traditional CV risk factors.Methods and results
In a cross-sectional study, atherosclerosis burden was compared between 112 female SLE patients and 31 controls. Plaque number and carotid intima-media wall thickness (cIMT) were assessed by ultrasonography. In a retrospective study, BMD determinations obtained 5-years before the ultrasonography assessment were analyzed in a subgroup of 62 patients. Plaque frequency was increased in SLE, even in patients without CV events or carotid wall thickening. cIMT was increased in patients with CVD, positively correlated with body mass index (BMI). Interestingly, a paradoxical effect of BMI on carotid parameters was observed. Whereas underweight patients (BMI < 20) showed increased prevalence of carotid plaques with low cIMT, those with BMI > 30 showed higher cIMT and plaque burden. Overweight patients (25 < BMI<30) exhibited both elevated cIMT and plaque number. BMI was an independent predictor of BMD. In our retrospective study, patients with either clinical or subclinical CVD exhibited lower BMD levels than their CV-free counterparts. A low lumbar spine BMD independently predicted CVD development after adjusting for confounders.Conclusion
SLE was associated with a higher subclinical atherosclerosis burden, a bimodal effect being observed for BMI. Decreased BMD can be a CV risk biomarker in SLE. 相似文献10.