全文获取类型
收费全文 | 627篇 |
免费 | 30篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 45篇 |
妇产科学 | 10篇 |
基础医学 | 66篇 |
口腔科学 | 19篇 |
临床医学 | 49篇 |
内科学 | 89篇 |
皮肤病学 | 2篇 |
神经病学 | 60篇 |
特种医学 | 49篇 |
外科学 | 188篇 |
综合类 | 7篇 |
预防医学 | 14篇 |
眼科学 | 12篇 |
药学 | 21篇 |
肿瘤学 | 15篇 |
出版年
2024年 | 1篇 |
2023年 | 7篇 |
2022年 | 8篇 |
2021年 | 18篇 |
2020年 | 11篇 |
2019年 | 12篇 |
2018年 | 9篇 |
2017年 | 10篇 |
2016年 | 16篇 |
2015年 | 23篇 |
2014年 | 22篇 |
2013年 | 41篇 |
2012年 | 41篇 |
2011年 | 34篇 |
2010年 | 16篇 |
2009年 | 16篇 |
2008年 | 48篇 |
2007年 | 39篇 |
2006年 | 33篇 |
2005年 | 39篇 |
2004年 | 38篇 |
2003年 | 36篇 |
2002年 | 21篇 |
2001年 | 13篇 |
2000年 | 12篇 |
1999年 | 14篇 |
1998年 | 7篇 |
1997年 | 1篇 |
1996年 | 4篇 |
1995年 | 2篇 |
1994年 | 2篇 |
1993年 | 5篇 |
1992年 | 3篇 |
1991年 | 12篇 |
1990年 | 9篇 |
1989年 | 6篇 |
1988年 | 6篇 |
1987年 | 2篇 |
1985年 | 1篇 |
1984年 | 3篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1980年 | 3篇 |
1979年 | 1篇 |
1978年 | 4篇 |
1976年 | 1篇 |
1974年 | 2篇 |
1972年 | 1篇 |
1971年 | 1篇 |
1966年 | 3篇 |
排序方式: 共有659条查询结果,搜索用时 15 毫秒
1.
2.
Ozlem Coskun Serap Ucler Leyla Cavdar Levent E Inan 《Journal of clinical neuroscience》2007,14(4):334-339
Discontinuation of medication is the treatment of choice for patients with chronic daily headache (CDH) who overuse their medications. This treatment may be difficult due to increased headache severity observed in patients immediately after withdrawal. We retrospectively evaluated the efficacy of valproic acid therapy in 66 patients with overuse of CDH medication during withdrawal therapy. Patients were all withdrawn from medications and valproic acid started at 250 mg or 500 mg daily. Forty-two (63.6%) patients had decreased headache severity, including 27.3% objective responses in the first week. At the last visit in the 12th week, 50 patients were headache-free and only one patient had persistent headache. Fifteen patients withdrew from therapy due to side effects and lost to follow-up within this timeframe. Thus, low dose valproic acid appears to be safe and effective in the management of withdrawal therapy. 相似文献
3.
4.
Intracranial subdural haematoma is a rare complication of spinal anaesthesia. This report describes the case of a 31-year-old woman who presented with post partum headache following spinal anaesthesia for caesarean section. Bilateral haematomata were evacuated via burr-holes performed under total intravenous anaesthesia and the patient made a complete and uneventful recovery. The recognized causes of subdural haematoma are discussed. 相似文献
5.
Sema Aydodu Ipek Akil Talha Akil Caner Kabasakal Refik Killi Sevgi Mir Rait Yaci 《Pediatrics international》2004,46(1):67-71
BACKGROUND: The aim of the present study was to investigate renal vascular resistive changes in children with different stages of liver cirrhosis without obvious renal failure. METHODS: Twenty-nine children (14 girls, 15 boys, mean age 11.6 years) with cirrhosis and 20 healthy children (mean age 10.3 years) were investigated for renal vascular resistance with Doppler ultrasonography, urinary sodium, N-acetyl-beta-D glucosaminidase (NAG) and microalbuminuria excretion. RESULTS: The measurements of renal resistive indexes (RRI) were significantly higher in cirrhotic patients than the control group (0.69 +/- 0.07 vs 0.62 +/- 0.02, P < 0.0001). RRI measurement was found to be increased in decompensated cirrhotic patients than in compensated cirrhotic patients (0.73 +/- 0.05 vs 0.67 +/- 0.08, P < 0.0001). A significant positive relationship was observed between RRI and child score (r = 0.53). Urine NAG/Cr ratio was significantly higher in cirrhotic patients than in the control subjects (P < 0.001). Microalbumin concentrations were increased in the patients with decompensated cirrhosis than in the controls (P = 0.02). Patients with ascites and portal hypertension showed increased RRI values. CONCLUSIONS: We conclude that patients with cirrhosis are at risk of renal deterioration, which can not be detected by serum urea, creatinine, and glomerular filtration rate. The increase of RRI is associated with the progress of hepatocellular disease, and also the development of ascites and portal hypertension. Elevated urinary sodium excretion, elevated urinary NAG/Cr ratio and microalbuminuria might have a prognostic value especially in patients with Child scores> 6. Hence, monitoring RRI is a non-invasive means of studying early renal hemodynamic alteration in childhood cirrhosis. 相似文献
6.
Belde KasapDemir Eren Soyaltn Seil Arslansoyuamlar Caner Alparslan Demet Alaygut
nder Yavacan Tülay Demircan Fatma Mutluba Cem Karadeniz 《Journal of clinical hypertension (Greenwich, Conn.)》2021,23(2):245
Patients with solitary kidneys (SKs) are at risk of hypertension (HT) and associated end‐organ damage. The authors aimed to evaluate whether children with congenital SKs (CSKs) have higher office, ambulatory, or central blood pressure (BP), increased arterial stiffness or left ventricular mass index, or any risk for arrhythmia. With this purpose, patients with CSK and healthy controls being followed up between January 2018 and June 2019 were enrolled in the study. Demographic, biochemical, and office blood pressure (BP) data were recorded. Then, ambulatory blood pressure monitoring (ABPM) and measurements of central BP (cBP), pulse wave velocity (PWV), and augmentation index (AIx@75) were obtained. Ventricular repolarization parameters were acquired by 12‐lead electrocardiography. Left ventricular mass index (LVMI) and abdominal aortic stiffness parameters including strain, pressure strain elastic modulus (Ep), and normalized Ep (Ep*) were calculated with echocardiographic measurements. Finally, 36 children with CSK and 36 healthy controls were included. Serum creatinine, uric acid, total cholesterol levels, ABPM parameters, cBP levels, and PWV values were significantly higher, and eGFR levels were significantly lower in the CSK group. VR parameters, abdominal aortic stiffness indices, and LVMI were similar between the groups. CSK increased the risk of HT in ABPM (HTABPM) by 6 times. PWV was significantly correlated with Ep and Ep* in cases with CSK. Determination of cBP and PWV along with 24‐hour ABPM would be a useful tool in children with CSK. 相似文献
7.
8.
9.
M. Bavbek M.D. H. Caner M.D. H. Arslan M.D. B. Demirhan M.D. S. Tunçbilek M.D. N. Altinörs M.D. 《Infection》1998,26(3):181-183
Summary
Dermabacter species are commonly isolated from the skin and other body sites but rarely show pathogenicity in humans. A case ofDermabacter hominis cerebral abscess is reported which presented as a contrast-enhancing intracranial mass in a renal tranplant patient. 相似文献
10.
Kadir Serafettin Tekgunduz Mustafa Kara Ibrahim Caner Yasar Demirelli 《Iranian journal of pediatrics.》2015,25(4)