全文获取类型
收费全文 | 1265篇 |
免费 | 87篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 85篇 |
妇产科学 | 49篇 |
基础医学 | 193篇 |
口腔科学 | 19篇 |
临床医学 | 117篇 |
内科学 | 233篇 |
皮肤病学 | 59篇 |
神经病学 | 89篇 |
特种医学 | 13篇 |
外科学 | 160篇 |
综合类 | 55篇 |
预防医学 | 57篇 |
眼科学 | 24篇 |
药学 | 101篇 |
中国医学 | 5篇 |
肿瘤学 | 86篇 |
出版年
2023年 | 20篇 |
2022年 | 16篇 |
2021年 | 43篇 |
2020年 | 20篇 |
2019年 | 16篇 |
2018年 | 41篇 |
2017年 | 35篇 |
2016年 | 39篇 |
2015年 | 36篇 |
2014年 | 51篇 |
2013年 | 62篇 |
2012年 | 93篇 |
2011年 | 100篇 |
2010年 | 58篇 |
2009年 | 49篇 |
2008年 | 55篇 |
2007年 | 69篇 |
2006年 | 66篇 |
2005年 | 50篇 |
2004年 | 42篇 |
2003年 | 43篇 |
2002年 | 50篇 |
2001年 | 32篇 |
2000年 | 32篇 |
1999年 | 29篇 |
1998年 | 19篇 |
1997年 | 7篇 |
1996年 | 6篇 |
1995年 | 8篇 |
1994年 | 9篇 |
1993年 | 5篇 |
1992年 | 15篇 |
1991年 | 12篇 |
1990年 | 14篇 |
1989年 | 9篇 |
1988年 | 13篇 |
1987年 | 13篇 |
1986年 | 9篇 |
1985年 | 14篇 |
1983年 | 5篇 |
1981年 | 4篇 |
1979年 | 5篇 |
1977年 | 3篇 |
1974年 | 3篇 |
1973年 | 4篇 |
1971年 | 3篇 |
1970年 | 6篇 |
1969年 | 4篇 |
1968年 | 5篇 |
1965年 | 4篇 |
排序方式: 共有1359条查询结果,搜索用时 617 毫秒
1.
PC Chamyal A Mehta SL Ojha JR Bhardwaj 《Indian journal of otolaryngology and head and neck surgery》1991,43(1):26-27
Primary tuberculous pathology in nasolpolypi is a rare condition. A case of bilateral ethmoidal polypi with tubercular lesion diagnosed on histopathologlcal examination is being reported and the available relevant literature has been reviewed. 相似文献
2.
Immune responses induced by two dose strengths of an yeast-derived recombinant hepatitis B vaccine in adolescents. 总被引:2,自引:0,他引:2
3.
Neerja Sharma 《Early child development and care》1990,58(1):71-79
The infant is the youngest but perhaps the most valuable member of society. It has been unequivocally established through research that the period up to two years is the most potent for forming and establishing the basis of later development. This paper summarizes the findings of two research studies on infant care in India that began in July 1988 and culminated in March 1989 under my guidance. The two studies are linked in their final implications for infant stimulation and in their role in providing insights into changing trends in infant-care in India.
In study I patterns of infant caregiving practiced by fathers were investigated. Study II looked into infant-care practices in Punjabi families where the grandmother lived with the young parents. 相似文献
In study I patterns of infant caregiving practiced by fathers were investigated. Study II looked into infant-care practices in Punjabi families where the grandmother lived with the young parents. 相似文献
4.
5.
Kalpana Agarwal Anita Mukherjee Archana Sharma Ramesh Sharma Kuldip Raj Bhardwaj Soumitra Sen 《Environmental and molecular mutagenesis》1992,19(4):323-326
Fenfluramine, an amphetamine derivative used in the treatment of obesity, has been evaluated in vivo in the bone marrow cells of Swiss albino mice using two cytogenetic endpoints for assessing its genotoxic and clastogenic potentials. Concentrations of 0.75, 1.5, 3.0, and 5.0 mg/kg b.w. were administered orally for the study of sister chromatid exchange frequencies and chromosome aberrations (CA). SCE frequencies showed a positive dose response; 1.5 mg/kg being the minimum effective concentration. Fen caused a prolongation of cell cycle at all concentrations. Except for the minimum therapeutic dose (0.75 mg), all other doses (1.5, 3.0, and 5.0 mg) showed a significant increase in the percentage of damaged cells over that of the vehicle control. The degree of clastogenicity was directly proportional to the dosage used and inversely related with the duration of treatment. A gradual reduction of the clastogenic potential was observed after 12 and 24 hr of exposure, indicating that the maximum effect occurs at the middle or late synthetic phase of the cell cycle. This study, probably the first detailed screening of the drug for its genotoxicity, shows that Fen is moderately clastogenic and a DNA damaging agent in vivo. 相似文献
6.
Sanjeev Kumar Bhardwaj Poonam Sharma Gurcharan Kaur 《Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid》1998,35(1-3):187-202
The activities of the enzymes related to glutathione synthesis, degradation, and functions as well as reactive oxygen scavenging enzymes were analyzed in different brain regions, such as cerebral hemisphere, cerebellum, brainstem, thalamus, and hypothalamus after 1 and 3 mo of streptozotocin-induced diabetes in rats. Parallel studies were also made in age-matched control rats and insulin-treated diabetic rats. The content of glutathione (GSH) and its synthesizing enzyme γ-glutamylcystein synthetase and also superoxide dismutase (SOD) and catalase activities (reactive oxygen scavenging enzymes) were significantly decreased from almost all the brain regions studied. However, glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), γ-glutamyl transpeptidase (γ-GTP), and glutamine synthetase (GS) activities were increased in the diabetic rat brain. Insulin treatment to the diabetic rats resulted in partial to full recovery in these enzymes activities. The present results emphasize the potentially serious alterations of brain free radical scavenger system in uncontrolled Type I diabetes. 相似文献
7.
The cytokine tumor necrosis factor was originally identified as a protein that kills tumor cells. So far, 18 distinct members of this family have been identified. All of them regulate cell survival, proliferation, differentiation, and cell death, also called apoptosis. The apoptosis induced by TNF, and other members of the family, for example, FasL, VEGI, and TRAIL is mediated through death receptors. The apoptotic signals by these cytokines are transduced by eight different death domain- (DD) containing receptors (TNFR1, also called DR1; Fas, also called DR2; DR3, DR4, DR5, DR6, NGFR, and EDAR). The intracellular portion of all these receptors contains a region approximately 80 amino acids long referred to as the death domain. Upon activation by its ligand, the DD recruits various proteins that mediate both death and proliferation of the cells. These proteins in turn recruit other proteins via their DDs or death effector domains. The actual destruction of the cell, however, is accomplished by serial activation of a family of proteases referred to as caspases. Cell death is negatively regulated by a family of proteins that includes decoy receptors, silencer of DD, sentrin, cellular FLICE inhibitory protein, cellular inhibitors of apoptosis, and survivin. This review is an attempt to describe how these negative and positive players of cell death perform a harmonious dance with each other. 相似文献
8.
Chhabra M Bhardwaj M Ichhpujani RL Lal S 《Indian journal of pathology & microbiology》2005,48(2):190-193
Animal brain samples received at WHO Collaborating Centre laboratory at National Institute of Communicable Diseases (NICD) during the years 1991-2002 were tested by Seller's stain, Fluorescent Antibody Test (FAT) and Mouse Innoculation Test (MIT) as methods of rabies diagnosis. Negri bodies on Seller's staining could be detected in 52.5% of MIT positive brains, the concordance of this test with MIT was found to be 77.8%. FAT was positive in 91.5% of MIT positive brains, though it showed concordance of 95.7% with MIT results in the total samples. 12.2% of the samples were found positive by FAT of which 1/3rd also showed the presence of Negri bodies when MIT was negative i.e. showing that the virus is present in inactivated form. Thus emphasizing the need for timely and proper collection and transportation of specimens for testing. Seller's stain and FAT give reliable diagnosis of rabies in the brain samples in majority of the cases. MIT being time-intensive test, is of academic value only in decision making as regards initiation of Post Exposure Treatment (PET), it is recommended that in cases where Seller's stain and FAT have yielded negative results the decision to initiate PET should give due consideration to the nature and circumstances of the animal bite and other epidemiological features. 相似文献
9.
10.
Mathur SR Dahiya S Nayak A Bhatla N Singh MK 《Indian journal of pathology & microbiology》2004,47(3):333-335
We describe the clinicopathological and immunohistochemical findings in five cases of sclerosing stromal tumours of ovary and compare our findings with other reported cases of this uncommon tumour and with fibromas and thecomas which they may mimic. 相似文献