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"立交桥"高职护理人才培养模式初探 总被引:3,自引:1,他引:2
为探讨中等卫生学校毕业就读高等护理专业学生(即“立交桥”高职)的培养模式,在坚持高等教育培养目标及职业特色的前提下,结合学生特点,进行课程设置、教学方法及临床实践等方面的改革,以发挥学生的优势,弥补学生的不足,培养适应现代护理发展需要的高质量护理人才。 相似文献
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病例教学是根据教学目的和教学内容的要求,教师运用真实的病例或者经过精心设计的病例,将学生引入特定的情景中,引导学生对病例进行分析,提出问题,并解决问题的一种教学方法[1]。病例教学作为一种生动直观的教学形式[2],既能加深学生对理论知识的理解和记忆,也有利于实现教学方 相似文献
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Objective To observe the effects of gossypol on expressions of transforming growth factor-β1 (TGF-β1), fibronectin (FN) and 11β-hydroxysteroid dehydrogenase (11β-HSD) in nephridial tissue in rats with diabetes mellitus. Methods Thirty male Sprague-Dawley rats were randomly divided into three groups: normal control, type 2 diabetes and gossypol treatment group . After high-fat feeding for 4 weeks, the later two groups were injected with low dosage strepozotocin (30 mg/kg) intraperitoneally to induce type 2 diabetic rat model. The rats in gossypol treated group were given gossypol at the dosage of 15 mg/kg once per day for 4 weeks by gavage. And since the 5th week, the times of gavages had been changed into once per week at the same dosage and lasted to the 12th week . The levels of blood glucose, total cholesterol (TC), low density lipoprotein-cholesterol (LDL-c) were measured. Additionally, the morphological changes of the kidney were studied by light microscopy and transmission electron microscopy respectively. The mRNA expressions of TGF-β1, FN, 11β-HSD and 11β-HSD2 in nephridial tissue were assayed by semi-quantity RT-PCR. The protein expressions of TGF-β1 and FN in nephridial tissue were determined by immunohistochemistry. Results The blood levels of glucose, TC and LDL- c were increased significantly in type 2 diabetic group compared with normal control group(P<0. 01). The volume of glomerulus and the deposition of PAS positive substance in the glomerular interstitium were increased under light microscopy, and the glomerular basal membrane was thicker in type 2 diabetic group than those in normal control group under transmission electron microscopy. The mRNA and protein expressions of TGF-β1 and FN were increased(P<0. 01), and the mRNA expression of 11β-HSD2 was decreased(P<0. 05), while the mRNA expression of 11β-HSD1 was unchanged in type 2 diabetic group compared with normal control group. After the treatment of gossypol, the level of the blood glucose was significantly decreased(P< 0. 01), and the levels of TC, LDL-c showed a trend of decrease but had no statistical differences compared with type 2 diabetic group. The morphology of nephridial tissue was ameliorated in gossypol treatment group. The mRNA and protein expressions of TGF-β1 and FN were decreased(0. 16± 0. 02,0. 22±0. 05 ; 0. 24±0. 06,0. 33±0. 07, P< 0. 05), while the mRNA expressions of 11β-HSD1 and 11β-HSD2 were unchanged compared with type 2 diabetic group. Conclusions Gossypol can relieve the pathologic changes of nephridial tissue, inhibit the expressions of TGF-β1 and FN through decreasing blood glucose of rats with diabetes mellitus. 相似文献
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病例教学是根据教学目的和教学内容的要求,教师运用真实的病例或者经过精心设计的病例,将学生引入特定的情景中,引导学生对病例进行分析。提出问题,并解决问题的一种教学方法。病例教学作为一种生动直观的教学形式,既能加深学生对理论知识的理解和记忆,也有利于实现教学方式从灌输式向启发诱导式的转化,使学生自觉、主动、创造性的学习,培养学生批判性思维的能力。病例教学法以其独特的优势广泛应用于内、外、妇、儿等护理专业课的教学中,但由于缺乏与教材配套的教学病例,受教师的工作经验和知识水平的影响,病例教学在实际应用时出现了较大的随意性;规范性较差。现就病例教学法在护理专业课教学中应用体会介绍如下。[第一段] 相似文献
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目的:观察新生期卡介苗(BCG)和乙肝疫苗(HepB)联合接种对哮喘小鼠干扰素γ(IFN-γ)、白细胞介素4(IL-4)和白细胞介素17A(IL-17A)表达的影响,探讨BCG和HepB联合接种对气道炎症的影响及可能机制。方法:BALB/c小鼠随机分为BCG和HepB联合接种造模[卵清蛋白(OVA)所致哮喘模型]组(B/H/O组)、BCG接种造模组(B/O组)、HepB接种造模组(H/O组)、BCG和HepB联合接种组(B/H组)、造模组(OVA组)、BCG组、HepB组和生理盐水对照(NS)组,每组6只。B/H/O组和B/H组于第0、7和14天分3次皮下注射1×105CFU的BCG,同时第0和28天分2次下肢腿部肌肉注射HepB 1.5μg,其它组单独接种BCG或HepB。OVA致敏和雾化吸入激发建立哮喘模型;末次激发24 h后取肺组织HE染色;收集支气管肺泡灌洗液(BALF)进行细胞总数计数和嗜酸性粒细胞(EOS)计数;ELISA法检测血清IFN-γ和IL-4及肺组织匀浆IL-17A的水平。结果:肺组织病理观察发现,OVA组、B/O组、B/H/O组和H/O组支气管周围大量炎症细胞浸润,气道上皮细胞增生肥大,B/H/O组和H/O组的炎症程度较OVA组重,B/O组则较OVA组轻。B/H/O组、B/O组和H/O组BALF细胞总数与OVA组比较均下降(P0.05);EOS计数在B/H/O组比B/H组上升(P0.05),B/O组比BCG组上升(P0.05),H/O组比HepB组上升(P0.05)。分别与H/O组、OVA组和NS组比较,HepB组的血清IFN-γ/IL-4比值均升高(P0.05);分别与B/H/O组、B/O组、OVA组和NS组比较,B/H组的血清IFN-γ/IL-4比值均升高(P0.05)。与OVA组比较,B/H/O组和B/O组的肺组织匀浆IL-17A水平均下降(P0.05);与B/O组比较,B/H/O组的肺组织匀浆IL-17A水平进一步下降(P0.05)。结论:卡介苗和乙肝疫苗联合接种有助于减轻哮喘模型小鼠肺部的炎症反应,其机制可能与降低IL-4分泌、提高IFN-γ/IL-4水平和抑制IL-17A的表达有关。 相似文献