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1临床资料
患者女,22岁.临床表现:反复心慌头晕头痛10年,全身频发抽畜6年,加重伴非喷射性呕吐1年,呈间歇发作性精神障碍,心烦,坐卧不安,言语混乱7个月. 相似文献
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IL-10基因1082A/G多态性与前列腺癌的发生及其进展的相关性分析 总被引:1,自引:2,他引:1
牛文强 《国际检验医学杂志》2011,32(1):42-43
目的 调查湖北汉族人群中的IL-10启动子区1 082A/G位点单核苷酸基因多态性(SNP)分布情况,并探讨此基因多态性与前列腺癌(PC)及其进展程度之间的相关性.方法 收集湖北地区汉族98例PC患者(按UICC 2002 TNM分期标准,分为Ⅰ、Ⅱ、Ⅲ期3个亚组)和88例年龄相匹配的健康体检男性作为对照组.采用基因测... 相似文献
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Objective To evaluate the clinical value of free prostate antigen (FPSA) , total prostate specific antigen (TPSA) , FPSA / TPSA and serum hormones (PRL, FSH, LH, Prog, T, E2) combined with ECT bone imaging in patients with prostate carcinoma. Methods 44 healthy males, 75 patients of benign prostate disease (including 41 of benign prostatic hyperplasia (BPH) and 25 of HBP with acute urinary retention (BPH + AUR) surgery, 9 of acute prostatitis) , and 48 patients with prostate carcinoma were enrolled in this study. Their Gonadal hormones and TPSA, FPSA, FPSA / TPSA were measured. Results ①The level of TPSA and FPSA in patients with prostate carcinoma or benign prostate disease were significantly higher than in healthy control (t1=11.42, t2=12.01, P<0.01); ②hose in patients with prostate carcinoma were obviously higher than in patients with benign prostate disease (t1=10.69, t2=11.18, P<0.01); ③he ratio of FPSA/TPSA in patients with prostate carcinoma was obviously lower than those with BPH 0,=10.69, t2=11.18, P<0.01), but there were no significant differences between patients with BPH+AUR and acute prostatitis (t1=0.73, t2=0.62, P>0.05); ④he FSH and LH of gonadal hormones in patients with prostate carcinoma were obviously higher than in patients with benign prostate diseases and healthy control.鈶?Except patients having operation total correction, the gonadal hormones and FSH/LH, T in patients with prostate carcinoma having different treatment programs all had variances before and after therapy; ⑤TPSA and FPSA in patients with prostate carcinoma having bone metastasis were much higher than those without bone metastasis (t/TPSA=5.38, t/fpsA=4.26, P<0.01), the ratio of FPSA/TPSA between those two had no significant disparity (t=1.61, P>0.05). Conclusion here was great clinlical value of the determination of TPSA and FPSA in diagnosis of prostate carcinoma, identification of prostate carcinoma and benign prostate disease and in judgment of bone metastasis. The ratio of FPSA /TPSA <0.16 is a proper prediction index for diagnosis of prostate carcinoma, FPSA /TPSA might be <0.16 in healthy ones and patients with acute prostatitis or BPH ; but when FPSA / TPSA <0.16, the risk of prostate cancer would increase; Gonadal hormones is useful biomarkers in diagnosis and treatment in patients with prostate carcinoma. 相似文献
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目的 探讨大隐静脉高位结扎联合剥脱术(HLS)、超声引导射频消融术(RFA)和腔内激光闭合术(EVLA)对下肢静脉曲张(VVLE)患者预后及生活质量的改善程度.方法 收集2018年3月至2021年3月在烟台毓璜顶医院行手术治疗的1590例VVLE患者的临床资料,按照手术方式不同将患者分为HLS组(n=282)、RFA组... 相似文献
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目的对比分析丙型肝炎患者血清自身抗体、HCV RNA水平和AST/ALT比值,以进一步探讨丙型病毒性肝炎的发病机理。方法采用间接免疫荧光法测定抗核抗体(ANA)、抗平滑肌抗体(SMA)、抗线粒体抗体(AMA)和抗肝肾微粒体抗体(LKM),采用核酸扩增(PCR)荧光定量技术检测标本HCV RNA含量,并同时检测肝功能指标丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)。结果HCV RNA阳性组和HCV RNA阴性组自身抗体检出率差异无统计学意义(P〉0.05) 自身抗体阳性组和自身抗体阴性组中AST/ALT比值≥1检出率有显著性差异(P〈0.01) HCV RNA阳性组和HCVRNA阴性组AST/ALT比值≥1检出率有显著性差异(P〈0.01)。结论病毒的直接作用和自身免疫是HCV损伤机体的两个重要因素。 相似文献
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目的探讨外阴阴道假丝酵母菌病(VVC)致病菌株分布和药敏情况。方法对2005年12月至2008年12月在孝感市中心医院妇科门诊以阴道炎症状就诊者中,阴道分泌物真菌培养阳性的260例患者进行菌株调查和药敏分析。结果VVC致病菌株白假丝酵母菌占89.6%(233/260),非白假丝酵母菌占10.4%,白假丝酵母菌菌株与非白假丝酵母菌菌株药敏无明显差异,两性霉素B药敏率98.87%。结论VVC致病菌株仍以白假丝酵母菌占优势,非白假丝酵母菌对两性霉素耐药率无增加。 相似文献
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目的:分析孝感市中小学教师的健康状况,为预防保健工作提供依据.方法:对孝感市1348名中小学教师的健康体检资料进行分析.结果:在1348名体检者中,检出疾病人数891人,占67.10%;中小学教师主要疾病有高血脂、脂肪肝、高血压、肝胆肾结石、心电图异常、糖尿病等,高血脂排在男性的首位,宫颈糜烂排在女性主要疾病的前5位;高血脂、脂肪肝、糖尿病检出率男性明显高于女性,两者间的比较有统计学意义,而高血压、心电图异常、肝胆肾结石男女间无统计学意义.高血脂、脂肪肝、高血压、肝胆肾结石、糖尿病、心电图异常有随年龄的增长而升高的趋势.结论:根据中小学教师的健康状况和特点,采取针对性的预防保健措施. 相似文献
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目的探讨乳腺癌患者术后化疗后感染状况,并进行临床分析,为临床预防医院感染提供参考依据。方法以2009年1月-2013年1月医院收治的96例乳腺癌手术化疗后发生感染患者为研究对象,留取咽拭子、口腔溃烂组织、尿液、粪便、皮肤渗出液、血液等标本,采用常规的细菌鉴定及药敏试验,对其进行临床分析,找出引发术后化疗后感染的发病部位、病原菌及危险因素。结果 96例乳腺癌术后化疗感染患者中院内感染占42.71%,院外感染占57.29%;感染共121例次,感染类型以呼吸道感染为主,47例次占38.84%,其次为消化道感染36例次占29.75%;96例乳腺癌手术化疗后感染患者中检出病原菌以革兰阴性菌为主占45.45%,分别为铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌,分别占17.36%、15.70、12.40%。结论乳腺癌患者手术化疗后机体免疫力急剧下降,是医院感染的高危人群,医护人员应积极采取针对性措施,以避免或降低乳腺癌患者术后感染的发生。 相似文献
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<正>下肢深静脉血栓形成(deep vein thrombosis,DVT)根据血栓形成的累及范围分为两类:累及腘静脉、股静脉和髂静脉的血栓被归类为近端深静脉血栓,累及小腿中枢部(胫前静脉、胫后静脉、腓静脉)以及小腿肌肉(腓肠肌和比目鱼肌)深静脉为远端深静脉血栓[1]。小腿肌肉静脉血栓(calf muscular vein thrombosis,CMVT)占所有远端深静脉血栓的30%~50%[2]。 相似文献