从本土品牌看日化平民策略

中国日化市场经过几番洗牌正在形成新的格局，白领策略（中高档策略）和平民策略（向农村进军）的不同思路使日化行业开始出现两极分化。     

Pediatric intracranial aneurysms——clinical characteristics and therapeutic strategies

Objective To assess the radiological characteristics and therapeutic strategies of intracranial aneurysms in children. Methods From our dedicated neurovascular databank of patients, we reviewed 23 consecutive children who had 24 intracranial aneurysms. There were 14 boys and 9 girls with a mean age of 9.09 years ( range 1 - 14 years ). Results Intracranial aneurysms in children ≤ 14 years constituted 1.3% of all intracranial aneurysms. Internal Carotid artery (ICA) and middle cerebral artery (MCA) were the most frequent sites for aneurysms. About 58.3% of the aneurysms were complex, including dissecting, pseudoaneurysm, giant and fusiform aneurysm. 1/3 of all aneurysms were located in posterior circulation. Only 1 case had multiple aneurysms in this case series. Almost half of all cases presented with subarachnoid hemorrhage and others presented with mass effect. 14 cases underwent endovascular treatment. 4 patients received microsurgical therapy. 5 cases did not receive microsurgical or endovascular therapy, 2 of them whose aneurysms spontaneously thrombosed during follow up. One boy with left vertebral artery giant aneurysm died after endovascular therapy owing to gradual thrombosis in basilar artery. Another child had poor outcome because of rerupture of aneurysm before operation. Whereas the majority had a favorable outcome. Conclusions Intracranial aneurysms in children had many clinical and radiological characteristics different from those in adults : ( 1 ) remarkable male predominance; ( 2 ) ICA and MCA were the most common sites for aneurysms; (3) high incidence of large, traumatic, infectious, dissecting and fusiform aneurysms. (4)For pediatric intracranial aneurysms, both microsurgical approaches and endovascular treatment were effective. Endovaacular therapy was the best choice for complex aneurysms.     

三磷酸腺苷结合盒运转体A1与颈动脉粥样硬化斑块的关系

目的 探讨三磷酸腺苷结合盒运转体A1(ATP binding cassette transporter A1,ABCA1)在人颈动脉粥样硬化斑块中的表达变化及作用机制.方法 收集24例人颈动脉粥样硬化斑块标本和10例肠系膜动脉标本(对照组),采用RT-PCR测定ABCA1 mRNA和视黄酸X受体α(RXRα)mRNA表达水平,并采用Western Blot检测ABCA1及RXRα的蛋白表达水平.24例人颈动脉粥样硬化斑块标本按病理分级,比较病理组织为Ⅲ级和Ⅰ级动脉粥样硬化组织间ABCA1 mRNA、RXRαmRNA表达水平及蛋白表达水平.结果 颈动脉粥样硬化斑块组的ABCA1 mRNA(0.79±0.04)和RXRα mRNA(0.73±0.04)表达与对照组相比上调,差异有统计学意义(P＜0.05);ABCA1 mRNA与RXRα mRNA增加水平相关(P＜0.05);颈动脉粥样硬化斑块的ABCA1蛋白表达(0.22±0.03)下调水平与对照组(0.53±0.03)相比差异有统计学意义(P＜0.05);Ⅲ级和Ⅰ级动脉硬化斑块ABCA1mRNA、RXRα mRNA及蛋白表达水平差异有统计学意义(P＜0.05).结论 ABCA1及RXRα蛋白表达水平下调可能是进展性动脉粥样硬化损害的关键因素.     

亚甲蓝甘油合剂封闭治疗三叉神经痛108例

目的观察亚甲蓝甘油合剂封闭治疗三叉神经痛的临床疗效并探讨其治疗机制。方法按国际头面痛学会分类委员会确定的诊断标准,108例原发性三叉神经患者随机分为两组:A组为亚甲蓝甘油合剂组(n=54),B组为单纯甘油合剂组(n=54);采用徐贵印推荐的三维测角穿刺半月神经节进行封闭治疗,对治疗后1周、3个月和2年分别进行疗效评判和随访观察。结果两组治疗后1周、3个月优良率比较差异无统计学意义(P>0.05),两年后优良率比较差异有统计学意义(P<0.05);两组并发症没有明显差异,2例出现视力下降,3例因解剖变异未能穿刺成功,仅在卵圆孔周围进行了注射,外加眶下孔以及骸孔封闭。结论亚甲蓝甘油合剂用于治疗三叉神经痛远期疗效优于单纯甘油合剂,且亚甲蓝对神经未见明显损害(经2年随访)。     

公路粉尘对养路工健康的危害

我区为湖南山区,号称“有色金属之乡”。全区共养护公路2147km,其中沥青路490km,砂路1657km(占77.18％)。很多路面用选矿尾砂代替河沙作路面保护层。职工2138人,其中养路工1341人,共有227个工班,每个班约6人,人均养路6km。有碎石、清沟铲草、铺沙、扫路等工种,分工不固定。砂路维护靠手工作业,虽定期发放防尘纱布口罩,但使用率很低。1986年我们对部分养路工班进行卫生学调查和体检,报告如下。     

先兆子痫患者剖宫产时机的选择

先兆子痫患者剖宫产时机的选择二院妇产科李福芹齐凤兰赵晓春在妊娠高血压综合征中，先兆子痫处理得当与否，直接影响母婴预后。我院将剖宫产作为先兆子痫患者终止妊娠的主要手段，并将终止妊娠时间提前至孕３４周，既保障了围产儿的存活，又避免了母亲因病情恶化出现严...     

老年人多原发癌18例分析

多原发癌是指同一患者的单个或多个器官组织,同时或先后发生两个以上的原发癌。我院1972年4月至1987年8月,共收治60岁以上老年人恶性肿瘤589例,其中经病理证实的多原发癌18例。现分析报道如下:     

脸色腰段椎间盘突出症21例临床分析

胸腰段椎间盘突出症罕见,约占椎间盘突出的0.6％～4％。随着CT及MRI的应用,其发病率有增加的趋势。因其发病率低,报道较少。但由于病变位于脊髓圆椎段,其发病较下腰段椎间盘突出有很大的特殊性,故有必要结合我院近年收治的21例对其作一回顾性分析。1 临床资料     

胎儿对母亲情绪波动的反应

自从有人提出母亲的情绪可以影响妊娠之后,人们对母亲的情绪影响胎儿发育感兴趣。研究的重点集中在慢性长期的或严酷、强烈的激动(如丈夫死后)作用,而对较轻度、短期的改变作用如由于一次打击或意外事情引起未进行研究。一名27岁无并发症妊娠的健康妇女,在上检查床进行扫描检查时不慎向后倒在