全文获取类型
收费全文 | 187716篇 |
免费 | 12282篇 |
国内免费 | 721篇 |
专业分类
耳鼻咽喉 | 2560篇 |
儿科学 | 5097篇 |
妇产科学 | 3613篇 |
基础医学 | 24376篇 |
口腔科学 | 3783篇 |
临床医学 | 18505篇 |
内科学 | 39794篇 |
皮肤病学 | 2973篇 |
神经病学 | 18947篇 |
特种医学 | 6546篇 |
外国民族医学 | 13篇 |
外科学 | 27814篇 |
综合类 | 2542篇 |
现状与发展 | 3篇 |
一般理论 | 207篇 |
预防医学 | 14269篇 |
眼科学 | 5001篇 |
药学 | 12237篇 |
中国医学 | 215篇 |
肿瘤学 | 12224篇 |
出版年
2023年 | 746篇 |
2022年 | 1299篇 |
2021年 | 2994篇 |
2020年 | 1858篇 |
2019年 | 3045篇 |
2018年 | 3574篇 |
2017年 | 2596篇 |
2016年 | 2979篇 |
2015年 | 3614篇 |
2014年 | 5302篇 |
2013年 | 8188篇 |
2012年 | 11903篇 |
2011年 | 12747篇 |
2010年 | 7072篇 |
2009年 | 6554篇 |
2008年 | 11981篇 |
2007年 | 12761篇 |
2006年 | 12316篇 |
2005年 | 12615篇 |
2004年 | 11981篇 |
2003年 | 11410篇 |
2002年 | 10996篇 |
2001年 | 1724篇 |
2000年 | 1335篇 |
1999年 | 1808篇 |
1998年 | 2442篇 |
1997年 | 2117篇 |
1996年 | 1781篇 |
1995年 | 1648篇 |
1994年 | 1497篇 |
1993年 | 1427篇 |
1992年 | 1206篇 |
1991年 | 1117篇 |
1990年 | 962篇 |
1989年 | 958篇 |
1988年 | 962篇 |
1987年 | 862篇 |
1986年 | 964篇 |
1985年 | 1051篇 |
1984年 | 1318篇 |
1983年 | 1270篇 |
1982年 | 1695篇 |
1981年 | 1559篇 |
1980年 | 1477篇 |
1979年 | 871篇 |
1978年 | 971篇 |
1977年 | 863篇 |
1976年 | 752篇 |
1975年 | 621篇 |
1974年 | 661篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
Elizabeth D. Krebs Robert B. Hawkins J. Hunter Mehaffey Clifford E. Fonner Alan M. Speir Mohammed A. Quader Jeffrey B. Rich Leora T. Yarboro Nicholas R. Teman Gorav Ailawadi 《The Journal of thoracic and cardiovascular surgery》2019,157(4):1533-1542.e2
Objectives
Expedient extubation after cardiac surgery has been associated with improved outcomes, leading to postoperative extubation frequently during overnight hours. However, recent evidence in a mixed medical-surgical intensive care unit population demonstrated worse outcomes with overnight extubation. This study investigated the impact of overnight extubation in a statewide, multicenter Society of Thoracic Surgeons database.Methods
Records from 39,812 patients undergoing coronary artery bypass grafting or valve operations (2008-2016) and extubated within 24 hours were stratified according to extubation time between 06:00 and 18:00 (day) or between 18:00 and 6:00 (overnight). Outcomes including reintubation, mortality, and composite morbidity-mortality were evaluated using hierarchical regression models adjusted for Society of Thoracic Surgeons predictive risk scores. To further analyze extubation during the night, a subanalysis stratified patients into 3 groups: 06:00 to 18:00, 18:00 to 24:00, and 24:00 to 06:00.Results
A total of 20,758 patients were extubated overnight (52.1%) and were slightly older (median age 66 vs 65 years, P < .001) with a longer duration of ventilation (4 vs 7 hours, P < .001). Day and overnight extubation were associated with equivalent operative mortality (1.7% vs 1.7%, P = .880), reintubation (3.7% vs 3.4%, P = .141), and composite morbidity-mortality (8.2% vs 8.0%, P = .314). After risk adjustment, overnight extubation was not associated with any difference in reintubation, mortality, or composite morbidity-mortality. On subanalysis, those extubated between 24:00 and 06:00 exhibited increased composite morbidity-mortality (odds ratio, 1.18; P = .001) but no difference in reintubation or mortality.Conclusions
Extubation overnight was not associated with increased mortality or reintubation. These results suggest that in the appropriate clinical setting, it is safe to routinely extubate cardiac surgery patients overnight. 相似文献3.
Interstitial cystitis/bladder pain syndrome (IC/BPS) and vulvodynia are chronic pain syndromes that appear to be intertwined from the perspectives of embryology, pathology and epidemiology. These associations may account for similar responses to various therapies. 相似文献
4.
5.
Michael E Egger Joanna M Ohlendorf Charles R Scoggins Kelly M McMasters Robert C G Martin II 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2015,17(9):839-845
BackgroundThe aim of this paper is to assess the current state of quality and outcomes measures being reported for hepatic resections in the recent literature.MethodsMedline and PubMed databases were searched for English language articles published between 1 January 2002 and 30 April 2013. Two examiners reviewed each article and relevant citations for appropriateness of inclusion, which excluded papers of liver donor hepatic resections, repeat hepatectomies or meta-analyses. Data were extracted and summarized by two examiners for analysis.ResultsFifty-five studies were identified with suitable reporting to assess peri-operative mortality in hepatic resections. In only 35% (19/55) of the studies was the follow-up time explicitly stated, and in 47% (26/55) of studies peri-operative mortality was limited to in-hospital or 30 days. The time period in which complications were captured was not explicitly stated in 19 out of 28 studies. The remaining studies only captured complications within 30 days of the index operation (8/28). There was a paucity of quality literature addressing truly patient-centred outcomes.ConclusionQuality outcomes after a hepatic resection are inconsistently reported in the literature. Quality outcome studies for a hepatectomy should report mortality and morbidity at a minimum of 90 days after surgery. 相似文献
6.
7.
Megan L. Robbins Robert C. Wright Ana María López Karen Weihs 《Journal of psychosocial oncology》2019,37(2):160-177
AbstractObjectives: This study examined word use as an indicator of interpersonal positive reframing in daily conversations of couples coping with breast cancer and as a predictor of stress.Design: The Electronically Activated Recorder (EAR) and Linguistic Inquiry and Word Count (LIWC) were used to examine naturally occurring word use conceptually linked to positive reframing (positive emotion, negative emotion, and cognitive processing words).Sample: Fifty-two couples coping with breast cancer.Methods: Couples wore the EAR, a device participants wear, that audio-recorded over one weekend (>16,000 sound files), and completed self-reports of positive reframing (COPE) and stress (Perceived Stress Scale). LIWC, a software program, measured word use.Findings: Both partners’ word use (i.e., positive emotion and cognitive processing words) was associated with their own reported positive reframing, and spouses’ word use was also indicative of patients’ positive reframing. Results also revealed that, in general, words indicating positive reframing predicted lower levels of stress.Conclusions: Findings supported the hypothesis that partners—and particularly spouses of breast cancer patients—may assist each other’s coping by positively reframing the cancer experience and other negative experiences in conversation. 相似文献
8.
9.
10.