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1.
Effects of granulocyte colony-stimulating factor on bacterial translocation due to burn wound sepsis
Orhan Yalçin Gürsel Soybir Ferda Köksoy Hakki Köse Recep Öztürk Baki Çokne§eli 《Surgery today》1997,27(2):154-158
The presence of certain defects in both cellular and humoral immunity after thermal injury has been established. Likewise,
the translocation of enteric bacteria to the mesenteric lymph nodes and to distant organs has also been observed following
serious thermal injury. The effects of granulocyte colony-stimulating factor (G-CSF) on bacterial translocation, the small
bowel mucosa, and cecal bacterial content were investigated in a rat model of burn wound sepsis in which albino Wistar rats
were scalded over 30% of their bodies, after which the lesions were infected by 1×108 colony-forming units (cfu)Pseudomonas aeruginosa. The control group was treated with 5% dextrose solution subcutaneously starting 2 days preburn, while the treatment group
received 100μg/kg human G-CSF subcutaneously. On the 4th day post burn all animals were killed to examine the bowel and culture
of the mesenteric lymph nodes (MLN), livers, and spleens. No significant differences were observed between the groups regarding
the cecal bacterial content and small bowel; however, a difference was seen in the ratio of translocation in the MLN liver
and spleen and quantitative MLN cultures. Based on these findings, G-CSF was thus found to be significantly effective in reducing
bacterial translocation due to burn wound sepsis. 相似文献
2.
3.
Progressive pseudorheumatoid chondrodysplasia: a hereditary disorder simulating rheumatoid arthritis 总被引:1,自引:0,他引:1
Progressive pseudorheumatoid chondrodysplasia is a rare hereditary disorder. This autosomal recessive condition is characterised by progressive arthropathy and platyspondyly. The symptoms are similar to those of rheumatoid arthritis but synovitis is absent. In this study a patient with inherited progressive pseudorheumatoid chondrodysplasia is presented. 相似文献
4.
Takuma?AkimotoEmail author Shuichi?Hashimoto Katsuhisa?Sunada 《Odontology / the Society of the Nippon Dental University》2016,104(3):390-396
Dexmedetomidine hydrochloride (DEX) is a α2-adrenergic receptor agonist that causes vasoconstriction by acting on α2B-adrenergic receptors in peripheral blood vessels. The authors aimed to determine the influence of DEX on tissue distribution, anesthetic action, and hemodynamic effects of lidocaine in rats. The investigators injected indigo carmine-containing 14C-labeled lidocaine hydrochloride (2 %) without and with 3.1, 12.5, or 50 μg/mL DEX or 10 μg/mL epinephrine into the right palatal mucosa mesial to the maxillary first molar of specific pathogen-free male Wistar rats. Autoradiography and liquid scintillation counting were performed to evaluate 14C-labeled lidocaine concentrations in the palatal mucosa, maxillary bone, maxillary nerve, and peripheral blood. Somatosensory-evoked potentials were measured to analyze anesthetic action, and blood pressure and pulse rate were measured to compare hemodynamic effects. DEX extended the tissue distribution of lidocaine in a concentration-dependent manner. Lidocaine with 12.5 μg/mL DEX had similar blood peak arrival time and peak-to-peak amplitude as lidocaine with 10 μg/mL epinephrine, but it reduced pulse rate. The results of this study suggest that 12.5 μg/mL DEX improves tissue distribution, anesthetic action, and hemodynamic effects of lidocaine in rats. Therefore, 12.5 μg/mL DEX may be a suitable alternative to epinephrine in lidocaine formulations, especially for patients with ischemic heart disease and hypertension. 相似文献
5.
6.
Dr. Jürgen Rei§ 《Archives of toxicology》1972,29(3):265-266
Zusammenfassung Die drei wichtigen Inhaltsstoffe von Haschisch, Cannabidiol, Tetrahydrocannabinol und Cannabinol, lassen sich auf vier verschiedenen Kieselgel-Fertigplatten nach Entwicklung mit Toluol und Besprühen mit 0,1% wäßriger Lösung von Fastblue B voneinander trennen. Eine Vorbehandlung der Platten mit Diäthylamin ist erforderlich. Die einzelnen Rf-Werte werden angegeben. 相似文献
7.
Kayhan Kuzeyli Soner Duru Ertuğrul Çakir Süleyman Baykal Sava§ Ceylan Fadil Aktürk 《Neurosurgical review》1996,19(2):109-112
Intradiploic epidermoid-tumor of the occipital bone was presented. There were neither intracranial extensions nor neurologic deficits. The lesion started as a painless mass under the scalp.The total removal of the tumor was associated with a good prognosis. 相似文献
8.
A case of solitary plasmacytoma of the skull is presented. The tumor was radically removed. There was no systemic involvement and the patient was not submitted to radiotherapy. Lytic lesions of the skull are discussed. 相似文献
9.
R. Topaloĝlu A. Bakkaloĝlu Ü. Saatçi N. Be§ba§ 《International urology and nephrology》1990,22(3):223-226
A case of primary hyperoxaluria is presented. In a product of consanguinous marriage recurrent stone formation, nephrocalcinosis
and increased urinary oxalate excretion revealed the diagnosis of hyperoxaluria. Diagnosis and treatment of primary hyperoxaluria
are briefly reviewed and the importance of elevated urinary oxalate level in diagnosis is emphasized. 相似文献
10.
Osman Faruk Şenyüz Nur Danişmend Ergun Erdoğan Gül§en Özbay Cenk Büyükünal 《Pediatric surgery international》1988,3(1):74-75
Total intestinal aganglionosis is the rarest form of Hirschsprung's disease, with absence of ganglia from the duodenum to the rectum. In addition to those cases reported in the literature, a neonate with total intestinal aganglionosis with involvement of the stomach is presented. Diagnosis of this extensive form of Hirschsprung's disease is a major problem. These patients lie beyond the scope of present surgical expertise, and the outcome is universally fatal. 相似文献