全文获取类型
收费全文 | 32138篇 |
免费 | 2352篇 |
国内免费 | 114篇 |
专业分类
耳鼻咽喉 | 335篇 |
儿科学 | 653篇 |
妇产科学 | 623篇 |
基础医学 | 4435篇 |
口腔科学 | 876篇 |
临床医学 | 3597篇 |
内科学 | 6369篇 |
皮肤病学 | 728篇 |
神经病学 | 3364篇 |
特种医学 | 1619篇 |
外国民族医学 | 1篇 |
外科学 | 4638篇 |
综合类 | 347篇 |
一般理论 | 18篇 |
预防医学 | 2311篇 |
眼科学 | 697篇 |
药学 | 1868篇 |
中国医学 | 69篇 |
肿瘤学 | 2056篇 |
出版年
2023年 | 203篇 |
2022年 | 388篇 |
2021年 | 766篇 |
2020年 | 521篇 |
2019年 | 640篇 |
2018年 | 836篇 |
2017年 | 661篇 |
2016年 | 824篇 |
2015年 | 902篇 |
2014年 | 1181篇 |
2013年 | 1560篇 |
2012年 | 2284篇 |
2011年 | 2161篇 |
2010年 | 1296篇 |
2009年 | 1157篇 |
2008年 | 1922篇 |
2007年 | 2007篇 |
2006年 | 1935篇 |
2005年 | 1834篇 |
2004年 | 1632篇 |
2003年 | 1499篇 |
2002年 | 1363篇 |
2001年 | 511篇 |
2000年 | 440篇 |
1999年 | 478篇 |
1998年 | 289篇 |
1997年 | 258篇 |
1996年 | 179篇 |
1995年 | 156篇 |
1994年 | 150篇 |
1993年 | 131篇 |
1992年 | 291篇 |
1991年 | 265篇 |
1990年 | 256篇 |
1989年 | 219篇 |
1988年 | 251篇 |
1987年 | 234篇 |
1986年 | 232篇 |
1985年 | 202篇 |
1984年 | 181篇 |
1983年 | 174篇 |
1982年 | 133篇 |
1981年 | 127篇 |
1980年 | 107篇 |
1979年 | 183篇 |
1978年 | 132篇 |
1976年 | 123篇 |
1975年 | 120篇 |
1974年 | 135篇 |
1973年 | 105篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
The association between family affluence and smoking among 15‐year‐old adolescents in 33 European countries,Israel and Canada: the role of national wealth 下载免费PDF全文
3.
Tobias Kisch Julia Maria Klemens Katharina Hofmann Eirini Liodaki Matthias Gierloff Dirk Moellmeier Felix Stang Peter Mailaender Jens Habermann Matthias Brandenburger 《Medicine》2015,94(41)
The regrowth of amputated digit tips represents a unique regenerative healing in mammals with subcutaneous volume regrowth, restoration of dactylogram, and suppression of scar formation. Although factor analysis in amphibians and even in mice is easy to obtain, safety of harvesting biomaterial from human digit tip amputations for analysis has not yet been described.The aim of this study was to evaluate if recovering wound exudate does hamper clinical outcome or influence microbiologic or inflammation status.A predefined cohort of 18 patients with fresh digit tip amputations was randomly assigned to receive standard therapy (debridement, occlusive dressing) with (n = 9) or without (n = 9) collection of the whole wound exudate in every dressing change. Primary endpoint (lengthening) and secondary endpoints (regeneration of dactylogram, nail bed and bone healing, time to complete wound closure, scar formation, 2-point discrimination, microbiologic analysis, inflammatory factors interleukin (IL)-1α, tumor necrosis factor-α, IL-4, and IL-6) were determined by an independent, blinded observer.Patients’ characteristics showed no significant differences between the groups. All patients completed the study to the end of 3 months follow-up. Exudate collection did not influence primary and secondary endpoints. Furthermore, positive microbiologic findings as well as pus- and necrosis-like appearance neither impaired tissue restoration nor influenced inflammatory factor release.Here, the authors developed an easy and safe protocol for harvesting wound exudate from human digit tip amputations. For the first time, it was shown that harvesting does not impair regenerative healing. Using this method, further studies can be conducted to analyze regeneration associated factors in the human digit tip.DRKS.de Identifier: DRKS00006882 (UTN: U1111-1166-5723). 相似文献
4.
5.
Prevalence of H pylori associated 'high risk gastritis' for development of gastric cancer in patients with normal endoscopic findings 总被引:1,自引:0,他引:1
Andreas Leodolter Matthias P Ebert Ulrich Peitz Kathlen Wolle Stefan Kahl Peter Malfertheiner 《World journal of gastroenterology : WJG》2006,(34)
INTRODUCTION H pylori infection is an established risk factor for development of gastric cancer[1,2]. According to the model of carcinogenesis of the intestinal type adenocarcinoma proposed by Correa, the multi-step development starts from the condition o… 相似文献
6.
Elhaji Youssef A.; Stoica Ileana; Dennis Sheldon; Purisima Enrico O.; Lumbroso Rose; Beitel Lenore K.; Trifiro Mark A. 《Human molecular genetics》2006,15(9):1561
Human Molecular Genetics (2006) 15, 921931; 相似文献
7.
Jill Downie Rose Chapman Angelica Orb Dianne Juliff 《The Australian journal of advanced nursing》2002,19(3):15-24
The traditional role of the high school based community community health nurse has changed considerably over recent decades. This article describes a qualitative study, in which nine community health nurses from eight different high schools completed a diary of the interventions and events during the course of two working days in order to identify the dimensions of their role. A short demographic questionnaire was also completed by the nurses and included two open-ended questions concerning their main professional issues and concerns. The researchers sought verification of the interpretation of the data through a focus group interview with the high school nurses. Data analysis indicated that the role of the high school community health nurses (CHN) consisted of seven categories. These were provider of clinical care, counsellor/ mediator, advocacy and support, liaison/referral, health promotion/education and resource agent, and professional management and research role. The findings highlight the complex and demanding aspects of the role of the high school nurse and articulate the importance of describing the contribution of such practitioners in to the promotion of health among adolescents. 相似文献
8.
M. D. Taylor M. L. de Ceballos S. Rose P. N. Chong P. Jenner C. D. Marsden 《Journal of neural transmission (Vienna, Austria : 1996)》1991,3(2):99-108
Summary Aged common marmosets were treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP; 0.5–2.0 mg/kg/week i.p.) for 16 or 24 weeks, observed for a total of 30 weeks and then killed for measurement of biochemical pramaters in basal ganglia. The MPTP treatment induced a marked depletion in dopamine, 3,4-dihydroxyphenylacetic acid and homovanillic acid levels in the caudate nucleus and putamen. In contrast, the concentrations of five neuropeptides: [Met5]-enkephalin, [Leu5]-enkephalin, cholecystokinin, substance P and neurotensin as measured by a combined HPLC/RIA method, remained unaltered in all basal ganglia regions examined. Enkephalin precursor levels, as reflected by cryptic [Met5]-enkephalin content, were increased in the putamen, but not in the caudate nucleus, as a consequence of MPTP administration. Cryptic [Leu5]-enkephalin content remained unchanged in the striatum of MPTP treated marmosets. Overall, these results suggest an increase in striatal [Met5]-enkephalin release following chronic MPTP treatment of aged marmosets. However, the chronic treatment of aged marmosets with MPTP does not reproduce the neuropeptide alterations characteristic of Parkinson's disease. 相似文献
9.
J W Rose H Lorberboum-Galski D Fitzgerald R McCarron K E Hill J J Townsend I Pastan 《Journal of neuroimmunology》1991,32(3):209-217
IL2-PE40 is a chimeric protein composed of human interleukin-2 (IL2) genetically fused to a modified form of Pseudomonas exotoxin lacking the cell recognition domain. IL2-PE40 is cytotoxic for IL2 receptor-bearing lymphocytes in culture and can inhibit activation of T cells in vivo. IL2-PE40 can significantly diminish antigen-stimulated proliferation of lymphocytes sensitized to myelin basic protein. Intraperitoneal administration of IL2-PE40 not only markedly inhibits the clinical manifestations of adoptively transferred relapsing experimental allergic encephalomyelitis but also dramatically reduces both inflammation and demyelination characteristic of the disease. 相似文献
10.
OBJECTIVE: To assess the outcome of the surgical treatment of patients who had adrenalectomy for phaeochromocytoma. DESIGN: Retrospective clinical study. SETTINGS: University hospital, Germany. SUBJECTS: 87 consecutive patients with phaeochromocytoma who were operated on. INTERVENTIONS: 29 flank and 58 transabdominal adrenalectomies between 1974 and 2000. RESULTS: The mean tumour diameter was 5 cm (range 2-13), and the mean weight 91 g (range 7-550). The postoperative hospital stay was 11 days. The flank incision entailed the shortest operating time (95 minutes). Two of the phaeochromocytomas were malignant. There were two wound infections but no deaths. With a correct selection of patients, a flank incision is safe. Endoscopic retroperitoneal adrenalectomies should be preferred. 相似文献