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排序方式: 共有57条查询结果,搜索用时 15 毫秒
1.
Lithium treatment of chronic hair pulling 总被引:3,自引:0,他引:3
G A Christenson M K Popkin T B Mackenzie G M Realmuto 《The Journal of clinical psychiatry》1991,52(3):116-120
Ten patients with chronic hair pulling received trials of lithium carbonate of 2 to 14 months' duration. Eight patients demonstrated decreased hair pulling and mild to marked hair regrowth. Three responders experienced increased hair pulling subsequent to discontinuation of lithium treatment. Lithium's effect on hair pulling may be related to its observed benefits in treating aggressivity, impulsivity, and mood instability. 相似文献
2.
Bucello Sebastiano Annovazzi Pietro Ragonese Paolo Altieri Marta Barcella Valeria Bergamaschi Roberto Bianchi Alessia Borriello Giovanna Buscarinu Maria Chiara Callari Graziella Capobianco Marco Capone Fioravante Cavalla Paola Cavarretta Rosella Cortese Antonio De Luca Giovanna Di Filippo Massimiliano Dattola Vincenzo Fantozzi Roberta Ferraro Elisabetta Filippi Maria Maddalena Gasperini Claudio Grimaldi Luigi Maria Edoardo Landi Doriana Re Marianna Lo Mallucci Giulia Manganotti Paolo Marfia Girolama Alessandra Mirabella Massimiliano Perini Paola Pisa Marco Realmuto Sabrina Russo Margherita Tomassini Valentina Torri-Clerici Valentina Liliana Adriana Zaffaroni Mauro Zuliani Cristina Zywicki Sofia Filippi Massimo Prosperini Luca 《Journal of neurology》2021,268(8):2922-2932
Journal of Neurology - To identify baseline factors associated with disease activity in patients with relapsing–remitting multiple sclerosis (RRMS) under teriflunomide treatment. This was an... 相似文献
3.
An integrated components preventive intervention for aggressive elementary school children: the early risers program 总被引:1,自引:0,他引:1
August GJ Realmuto GM Hektner JM Bloomquist ML 《Journal of consulting and clinical psychology》2001,69(4):614-626
The Early Risers prevention program aims to alter the developmental trajectory of children with early onset aggressive behavior. The program features 4 CORE components: (a) an annual 6-week summer school program, (b) a teacher consultation and student mentoring program, (c) child social skills groups, and (d) parent education and skills-training groups, all delivered in tandem with a FLEX family support program individually tailored to address the unique needs of families. At baseline, the mean age of the sample was 6.6 years. Following 2 years of intervention, program children showed significant improvement relative to controls in academic achievement and school behaviors. Change on behavioral self-regulation was moderated by level of child aggression, with intervention effects found for only the most severely aggressive children. Parents with high program attendance rates showed improvement in discipline methods. 相似文献
4.
S. Hossein Fatemi Amelia Merz George R. Realmuto 《Journal of developmental and physical disabilities》2003,15(1):1-22
This review describes involvement of serotonin, Reelin, and Bcl2 in cerebellar pathology in autism. The literature regarding neurochemical, neuropathologic, and imaging aspects of autistic pathology as related to cerebellum is discussed. Where appropriate, relevant animal data are also presented to explain the impact of environmental and genetic influences on development of autism. 相似文献
5.
Surveys of sexual behavior in autism suggest a variety of behavioral expression. However, the course of sexual development in autism is unplotted, leaving questions about the normalcy of specific behaviors. Even less is known about deviations of sexual development and the incidence of paraphilias in this population. We explore the problems of definition of sexual behaviors and describe a case report that highlights the difficulties of management. An application of a testosterone-suppressing medication and its effect on sexual behavior are reported. After failure of behavioral and educational programs, leuprolide, an injectable antiandrogen, resulted in suppression of behaviors and retention of the participants' community placement. Follow-up for almost 3 years shows no abnormal physical effects. Dosage has been tapered over that period to a low but effective dose. Directions for research are discussed. 相似文献
6.
George M. Realmuto Jonathan B. Jensen Elizabeth Reeve Barry D. Garfinkel 《Journal of autism and developmental disorders》1990,20(4):455-465
Studies have shown abnormal pituitary hormone responses to neuroendocrine agonists in autistic subjects. Two probes (clonidine and L-Dopa) were used to investigate neuroendocrine responses through changes in growth hormone levels. Seven medication-free autistic subjects (ages 6.6 to 19.1) were evaluated and compared to 14 normal controls. Growth hormone was collected at 30-min intervals during the entire study. Clonidine was administered first (dose: 0.15 mgm
2
), and samples were collected for 180 min. L-Dopa was then administered (dose: 250 mg for subjects <70 lb and 500 mg for subjects >70 lb), and samples were collected for 120 min. There was no difference in the amplitude of the clonidine or L-Dopa peak growth hormone responses in the control versus the autistic subjects. In the autistic subjects, the L-Dopa-stimulated growth hormone peak was delayed and the clonidine growth hormone peak was premature. A statistical difference with the control subjects was found when consideration was given to both the premature response of growth hormone to clonidine and the delayed response to L-Dopa (p=.01, Fisher's Exact Test). These findings suggest possible abnormalities of both dopaminergic and noradrenergic neurotransmission in subjects with autism.The authors thank Dorothee Aeppli for statistical consultation, Mary Bennett for clerical assistance, Lois Laitinen for secretarial support, and the Twin Cities Society for Autistic Children for access to patient recruitment. This study was supported in part by a grant from the Alex Kunin Foundation. 相似文献
7.
George M. Realmuto Ann Masten Linda Flies Carole Jon Hubbard Andrea Groteluschen Bunkhean Chhun 《Journal of traumatic stress》1992,5(4):589-599
Cambodian adolescents who survived massive trauma as children were studied to examine the relation of current trauma symptoms to sex, age, trauma exposure, and other current symptoms. Exposure to traumatic life events was expected to be very high, to relate to age and to other symptoms of current psychological functioning. Questionnaires assessed traumatic life events, post-traumatic stress disorder (PTSD) and other psychiatric symptoms, and current functioning. Results document high levels of stress exposure and current trauma symptoms. Based on self-reports of PTSD symptoms, 37% of the subjects were estimated to fulfill DSM-III-R criteria for PTSD. Trauma symptoms were correlated with exposure (r=.31), although not with symptoms of depressed mood, anxiety, or dissociation. Age was related to high levels of recollected trauma exposure (r=.56). Further studies are needed to identify factors associated with better outcomes and to plot the differential course of PTSD symptom clusters over time. 相似文献
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10.
A. Marmotti M. Bruzzone D. E. Bonasia F. Castoldi R. Rossi L. Piras A. Maiello C. Realmuto G. M. Peretti 《Knee surgery, sports traumatology, arthroscopy》2012,20(12):2590-2601