全文获取类型
收费全文 | 1142篇 |
免费 | 55篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 21篇 |
儿科学 | 44篇 |
妇产科学 | 29篇 |
基础医学 | 116篇 |
口腔科学 | 7篇 |
临床医学 | 211篇 |
内科学 | 159篇 |
皮肤病学 | 16篇 |
神经病学 | 70篇 |
特种医学 | 23篇 |
外科学 | 78篇 |
综合类 | 8篇 |
预防医学 | 226篇 |
眼科学 | 114篇 |
药学 | 44篇 |
中国医学 | 4篇 |
肿瘤学 | 28篇 |
出版年
2023年 | 5篇 |
2022年 | 11篇 |
2021年 | 28篇 |
2020年 | 12篇 |
2019年 | 27篇 |
2018年 | 29篇 |
2017年 | 21篇 |
2016年 | 13篇 |
2015年 | 15篇 |
2014年 | 23篇 |
2013年 | 44篇 |
2012年 | 70篇 |
2011年 | 93篇 |
2010年 | 39篇 |
2009年 | 36篇 |
2008年 | 64篇 |
2007年 | 70篇 |
2006年 | 54篇 |
2005年 | 86篇 |
2004年 | 55篇 |
2003年 | 57篇 |
2002年 | 63篇 |
2001年 | 18篇 |
2000年 | 17篇 |
1999年 | 15篇 |
1998年 | 10篇 |
1997年 | 10篇 |
1996年 | 5篇 |
1995年 | 8篇 |
1993年 | 7篇 |
1992年 | 26篇 |
1991年 | 21篇 |
1990年 | 13篇 |
1989年 | 14篇 |
1988年 | 13篇 |
1987年 | 17篇 |
1986年 | 20篇 |
1985年 | 9篇 |
1984年 | 5篇 |
1983年 | 13篇 |
1982年 | 4篇 |
1981年 | 3篇 |
1980年 | 5篇 |
1979年 | 3篇 |
1978年 | 5篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1974年 | 4篇 |
1971年 | 3篇 |
1965年 | 2篇 |
排序方式: 共有1198条查询结果,搜索用时 31 毫秒
1.
Balloon cell nevus of the iris 总被引:1,自引:0,他引:1
2.
Mohammed E Abushaiqa Frank K Zaran David S Bach Richard T Smolarek Margo S Farber 《American journal of health-system pharmacy》2007,64(11):1170-1173
PURPOSE: Educational interventions to reduce the use of abbreviations and dosage designations that were deemed unsafe at a level 1 trauma center are described. SUMMARY: Strategies to reduce the use of unsafe abbreviations at Detroit Receiving Hospital were studied. Six abbreviations and dosage designations were deemed as unsafe by the site's medication-use and patient medical safety committees: (1) U for units, (2) microg for microgram, (3) TIW for three times a week, (4) the degree symbol for hour, (5) trailing zeros after a decimal point, and (6) the lack of leading zeros before a decimal point. Data on abbreviation use was collected starting in September 2003 by examining copies of patients' order sheets, which are sent from nursing units to the pharmacy for processing. Data were collected during three 24-hour periods each month, with 7-10 days between each period. A data collection sheet was developed to assist in documenting the number of opportunities for each unsafe abbreviation and the actual incidence of each. Educational strategies were developed and implemented starting in October 2003 to decrease the use of the unsafe abbreviations. These strategies included inservice education programs for the medical, pharmacy, and nursing staffs; laminated pocket cards; patient chart dividers; stickers; and interventions by pharmacists and nurses during medication prescribing. During the eight-month evaluation period, 20,160 orders were reviewed, representing 27,663 opportunities to use a designated unsafe abbreviation. Educational interventions successfully reduced the overall incidence of unsafe abbreviations from 19.69% to 3.31%. CONCLUSION: Educational interventions markedly reduced the use of unsafe abbreviations in medication orders over an eight-month evaluation period. 相似文献
3.
4.
Validation of a self-administered diet history questionnaire using multiple diet records 总被引:25,自引:0,他引:25
Gladys Block Margo Woods Arnold Potosky Carolyn Clifford 《Journal of clinical epidemiology》1990,43(12):1327-1335
The validity of a self-administered diet history questionnaire has been estimated using as the reference data the mean of three 4-day diet records collected over the year prior to the administration of the questionnaire, in 1985–1986. Subjects were women ages 45–70 years, participants in the Women's Health Trial Feasibility Study, a multi-center clinical trial in which some women were randomized to be taught to adopt and maintain a low-fat diet, while others maintained their usual diet. The questionnaire produced group mean nutrient estimates closely approximating the values obtained by three 4-day records, e.g. in the usual-diet group, 37.7% of calories from fat by both food records and by questionnaire, and in the low-fat, group, 21.3% of calories from fat by food records and 23.7% of calories from fat by questionnaire. Correlations between questionnaire and diet records for per cent of calories from fat were 0.67 and 0.65 respectively in the two groups; most correlations were in the 0.5–0.6 range, and were similar to those achievable by a single 4-day food record. 相似文献
5.
Bilateral idiopathic inflammation of the optic nerve sheaths. Light and electron microscopic findings 总被引:1,自引:0,他引:1
Idiopathic perioptic neuritis is a term used to describe noninfectious inflammatory disorders of the optic nerve sheaths, the causes of which are unknown. In the following report, a 68-year-old woman with bilateral visual loss was found to have chronic inflammation with necrobiotic granulomas of her optic nerve sheaths. The patient, who had no systemic condition known to be associated with necrobiotic granuloma, lost vision from infarction of the optic nerve parenchyma and from compression due to thickened meninges. Although there are similarities between the inflammatory reaction in this case to the necrobiotic dermatoses, the pathogenesis of this condition remains obscure. 相似文献
6.
Perla A Vargas Pippa M Simpson Margo Bushmiaer Rajiv Goel Craig A Jones James S Magee Charles R Feild Stacie M Jones 《Annals of allergy, asthma & immunology》2006,96(6):787-793
BACKGROUND: Children with poorly controlled asthma are at high risk of airway remodeling, sleep disruption, school absenteeism, and limited participation in activities. OBJECTIVE: To determine asthma prevalence and characterize disease severity and burden in school-aged children. METHOD: A case-finding study was conducted via a multiple-choice questionnaire and asthma algorithm. Items used for analysis include physician diagnosis of asthma, symptom severity, and health care utilization. The chi2 test was used to determine the significance of differences among cases. Logistic regression was used to evaluate the association of patient factors and asthma indicators. RESULTS: Of the 5,417 children surveyed, 1,341 (25%) were classified as being at risk of asthma. Of these asthma cases, 55% were positive by diagnosis and algorithm (active), 10% were positive per algorithm alone (suspected), and 35% were positive per diagnosis alone (nonactive). Only 14% of all asthma cases reported experiencing no respiratory symptoms (< 1% active, 2% suspected, and 40% nonactive) compared with 75% of noncases. Also, 75% of noncases reported never missing school compared with 19%, 33%, and 54% of active, suspected, and nonactive asthma cases. African American race, Medicaid enrollment, and male sex were independent predictors of asthma risk. Similarly, African American race, Medicaid enrollment, age, and persistent asthma were independent predictors of emergency department use among asthma cases. DISCUSSION: Prevalence of active symptoms suggestive of poor asthma control was extremely high among urban, minority children enrolled in Arkansas' largest public school district. Poor asthma control greatly affects quality of life, including school attendance and performance. Interventions should raise expectations and emphasize the importance of achieving asthma control. 相似文献
7.
A statewide study was done with five associate degree (ADN) and five baccalaureate degree (BSN) nursing programs in Georgia to examine the similarities and differences in curriculum based on a nationally used model. From this overall study, select content related to community/home health care was evaluated in the sample programs. Professional standards for community and home health care nursing practice, as well as other published literature on the topic, provided a basis to determine competence to practice. Data were collected through a taped telephone interview to all program chairpersons (N = 10) and mailed questionnaires to faculty involved with all required courses (N = 110). Content analyses of responses allowed for evaluation of frequency of these learning activities between ADN and BSN programs and among BSN programs in the areas of family, teaching, interdisciplinary collaboration, physical assessment, and leadership. Overall, the results indicated lack of conclusive data to support a distinct difference in these educational components between the ADN and BSN sample or among BSN programs. The study was intended to service as a basis for home health care curriculum development in the future. 相似文献
8.
Allodynia in rats infected with varicella zoster virus—a small animal model for post-herpetic neuralgia 总被引:1,自引:0,他引:1
Robert G. Dalziel Sharon Bingham David Sutton Dawn Grant Jean M. Champion Shelley A. Dennis John P. Quinn Chas Bountra Margo A. Mark 《Brain Research Reviews》2004,46(2):234
The most common complication of herpes zoster is post-herpetic neuralgia (PHN), which has been defined as severe pain occurring 1 month after rash onset or persisting for greater than 3 months. PHN is classed as a neuropathic pain that is associated with mechanical allodynia where normally innocuous tactile stimuli are perceived as painful. The development of therapies to treat PHN has been hampered by the lack of animal models, which mimic the clinical situation. We have previously reported that varicella zoster virus (VZV) infection in the rat results in mechanical allodynia and thermal hyperalgesia. Here, we report that following VZV infection of the left footpad rats develop a chronic mechanical allodynia, which is present for longer than 60 days post-infection and which resolves by 100 days PI. The model is robust and reproducible with animals consistently developing allodynia by 3 days PI and continuing to present with symptoms for at least 30 days. The reproducible nature of the induction and course of the allodynia allows the use of this model to determine the effect of various compounds on, and to investigate the pathogenic mechanisms underlying the development of VZV-induced allodynia. Comparative studies using HSV-1 show that the induction of the chronic allodynia is VZV-specific and is not a result is of virus replication-induced tissue damage or accompanying inflammation.Therefore, we propose that the rat VZV infection model could prove useful in studying the mechanisms underlying post-herpetic neuralgia. 相似文献
9.
10.
Sequence-based typing of ade B as a potential tool to identify intraspecific groups among clinical strains of multidrug-resistant Acinetobacter baumannii 总被引:1,自引:0,他引:1
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Sequence analysis of an 850-bp fragment internal to the aspecific drug efflux gene ade B revealed 11 sequence types (STs) among a collection of 50 multidrug-resistant Acinetobacter baumannii (MDRAB) strains, including members of pan-European clones I, II, and III. The delineation of STs conformed with the intraspecific grouping of these strains previously determined by different DNA fingerprinting methods. Larger strain collections need to be screened to further explore the potential of sequence-based ade B typing as a universal tool for the monitoring of MDRAB clones. 相似文献