全文获取类型
收费全文 | 165篇 |
免费 | 6篇 |
国内免费 | 6篇 |
专业分类
儿科学 | 10篇 |
妇产科学 | 9篇 |
基础医学 | 13篇 |
临床医学 | 19篇 |
内科学 | 42篇 |
皮肤病学 | 3篇 |
神经病学 | 8篇 |
特种医学 | 6篇 |
外科学 | 31篇 |
预防医学 | 4篇 |
药学 | 15篇 |
肿瘤学 | 17篇 |
出版年
2022年 | 1篇 |
2021年 | 3篇 |
2019年 | 2篇 |
2018年 | 3篇 |
2017年 | 2篇 |
2016年 | 5篇 |
2015年 | 6篇 |
2014年 | 4篇 |
2013年 | 11篇 |
2012年 | 8篇 |
2011年 | 17篇 |
2010年 | 12篇 |
2009年 | 4篇 |
2008年 | 11篇 |
2007年 | 14篇 |
2006年 | 11篇 |
2005年 | 3篇 |
2004年 | 3篇 |
2003年 | 6篇 |
2002年 | 6篇 |
2001年 | 3篇 |
2000年 | 8篇 |
1999年 | 7篇 |
1998年 | 3篇 |
1997年 | 2篇 |
1994年 | 1篇 |
1992年 | 3篇 |
1988年 | 1篇 |
1987年 | 3篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1977年 | 1篇 |
1968年 | 1篇 |
1967年 | 2篇 |
1966年 | 2篇 |
1965年 | 6篇 |
排序方式: 共有177条查询结果,搜索用时 15 毫秒
1.
2.
3.
Leonardo Frazzoni Franco Radaelli Cristiano Spada Alessandro Mussetto Marzio Frazzoni Liboria Laterza Emanuele Rondonotti Marina La Marca Rocco Maurizio Zagari Stefania Piccirelli Franco Bazzoli Carlo Fabbri Mauro Manno Giovanni Aragona Gianpiero Manes Pietro Occhipinti Sergio Cadoni Cesare Hassan Lorenzo Fuccio 《Digestive and liver disease》2021,53(2):224-230
BackgroundColonoscopy demands a considerable amount of resources, and little is known about its diagnostic yield among inpatients.AimsTo assess indications, diagnostic yield and findings of colonoscopy for inpatients, and to identify risk factors for relevant findings and cancer.MethodsMulticentre, prospective, observational study including 12 hospitals. Consecutive adult inpatients undergoing colonoscopy were evaluated from February through November 2019.Results1,302 inpatients underwent colonoscopy. Diagnostic yield for relevant findings and cancer was 586 (45%) and 112 (8.6%), respectively. Adequate colon cleansing was achieved in 896 (68.8%) patients. Split-dose/same-day regimen was adopted in 847 (65%) patients. Factors associated to relevant findings were age ≥70 years (RR 1.32), male gender (RR 1.11), blood loss (RR 1.22) and adequate cleansing (RR 1.63). Age ≥70 years (RR 2.08), no previous colonoscopy (RR 2.69) and split-dose/same-day regimen (RR 1.59) significantly increased cancer detection. Implementing adequate cleansing and split-dose/same-day regimen in all patients would increase the diagnostic yield for any relevant findings and cancer from 43% to 70% and from 6% to 10%, respectively.ConclusionRelevant colorectal diseases and cancer were frequent among inpatients. Factors associated with detection of relevant findings were identified. Adequate colon cleansing and split-dose/same-day regimen significantly increased colonoscopy diagnostic yield. 相似文献
4.
Loreno M Bucceri AM Catalano F Muratore LA Blasi A Brogna A 《Digestive diseases and sciences》2004,49(3):404-407
We assessed the ultrasonographic pattern of gastric emptying in patients with functional dyspepsia, evaluating its relationship with symptoms. Twenty dyspeptic patients, with slight (group A) and severe (group B) symptoms, and 10 controls (group C) underwent ultrasonographic study of gastric emptying by measuring postprandial variations of the antral area at regular intervals. The time at which the antral area returned to the basal value was assumed to be the final emptying time. The final emptying time was significantly longer in both group A (294 +/- 42 min) and group B (340 +/- 36 min) compared to controls (244 +/- 21 min), but no significant difference was observed between them. A significantly (P < 0.05) greater dilation of the antral area was found at 50 min in group B compared to group A patients. A different pattern of antral motor function rather than a delay of gastric emptying correlates with the severity of symtoms in dyspeptic patients. 相似文献
5.
Penadés R Boget T Lomeña F Bernardo M Mateos JJ Laterza C Pavía J Salamero M 《Psychiatry research》2000,98(2):127-132
The role of cognitive variables was compared in two single cases of schizophrenia hypofrontality. SPECT procedures and neuropsychological tests were used to study frontal brain function. After cognitive rehabilitation, neuropsychological performance were enhanced in both patients, but only one of them showed enhanced the frontal blood flow. The brain perfusion changes after cognitive rehabilitation could be associated with the cognitive-dependent hypofrontality. 相似文献
6.
F Raspagliesi S Kusamura J C Campos Torres G A de Souza A Ditto F Zanaboni R Younan D Baratti L Mariani B Laterza M Deraco 《European journal of surgical oncology》2006,32(6):671-675
AIMS: We report the effects of cytoreductive surgery (CRS) and intraperitoneal hyperthermic perfusion (IPHP) in the treatment of advanced/recurrent epithelial ovarian cancer (EOC) on survival, morbidity and mortality. PATIENTS: Forty EOC patients were studied. Median age was 52.5 years (range: 30-68) and median follow-up 26.1 months (range: 0.3-117.6). Most patients presented advanced disease (stage III/IV). Previous systemic chemotherapy included cisplatin-based, taxol-based or taxol/platinum containing regimens. RESULTS: After the CRS, 33 patients presented no macroscopic residual disease. Five-year overall survival was 15%; the mean overall and progression-free survivals were 41.4 and 23.9 months, respectively. The morbidity, toxicity and mortality rates were 5%, 15% and 0%, respectively. CONCLUSION: Our results suggest that CRS + IPHP merits further evaluation by a formal prospective trial. 相似文献
7.
Neri M Milano A Laterza F Di Bonaventura G Piccolomini R Caldarella MP Balatsinou C Lapenna D Cuccurullo F 《Alimentary pharmacology & therapeutics》2003,18(8):821-827
BACKGROUND: The resistance of Helicobacter pylori to antibiotics has been advocated as a major cause of treatment failure, and antimicrobial sensitivity testing has been proposed to improve efficacy; however, its role before first-line therapy has not been investigated in detail. AIM: To assess whether antimicrobial sensitivity testing improves the eradication rate of first-line anti-Helicobacter treatments and to compare the effectiveness of ranitidine bismuth citrate and omeprazole in the presence of H. pylori resistance to antibiotics. METHODS: Two hundred and forty-two patients were assigned to either empirical or antimicrobial sensitivity testing-based treatment; within each group, subjects were further randomized to receive ranitidine bismuth citrate, 400 mg b.d., tinidazole, 500 mg b.d., and clarithromycin, 500 mg b.d., or omeprazole, 20 mg b.d., clarithromycin, 500 mg b.d., and amoxicillin, 1 g b.d., for 1 week, with substitution of the resistant antibiotic in the antimicrobial sensitivity testing-based treatment group. RESULTS: Eradication rates were 67% [confidence interval (CI), 55-79%] in the empirical treatment group and 76% (CI, 65-87%) in the antimicrobial sensitivity testing-based group (P=N.S.). The overall success rate was 60% (CI, 51-69%) with omeprazole and 82% (CI, 73-91%) with ranitidine bismuth citrate (P<0.03); the latter overcame antibiotic resistance in 12 of 15 strains vs. zero of eight strains by omeprazole. CONCLUSIONS: Antimicrobial sensitivity testing before first-line treatment does not improve the eradication rate, which is greater when ranitidine bismuth citrate is included in the treatment. 相似文献
8.
9.
10.
D. Fuster J. Magriña M. J. Ricart J. Pascual C. Laterza F. J. Setoain S. Vidal-Sicart J. J. Mateos F. Martín A. Muxí 《Transplant international》2000,13(5):327-332
This study was performed to determine the value of dipyridamole-99 mTc-methoxy-isobutyl isonitrile perfusion (99 mTC-MIBI) tomographic scintigraphy in the assessment of cardiac risk in patients being evaluated prior to combined pancreas-kidney
transplantation (PKT). We performed perfusion tomographic scintigraphy using single photon emission computed tomography (SPECT)
on 77 patients. The tomographic images did not show clinically relevant findings in 65 patients. In the remaining 12 patients,
coronary arteriography was performed: 2 showed normal results, 4 showed no stenosis, and 6 showed significant stenosis ( ≥
70 %). Seventy-two patients underwent PKT. During the follow-up (6–48 months), there were seven cardiac events, 4 patients
with significant stenosis, and 3 with nonsignificant stenosis upon coronary arteriography, and all had pathological tomographic
images. 99 mTc-MIBI tomographic scintigraphy may be useful in identifying patients at low risk of incurring cardiac events after PKT and
may, in a large group of patients, obviate the need for routine coronary angiography.
Received: 6 July 1999/Revised: 11 January 2000/Accepted: 30 May 2000 相似文献