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排序方式: 共有312条查询结果,搜索用时 312 毫秒
1.
This paper examines the effects of intraocular epinephrine on systemic blood pressure and heart rate during cataract surgery. Sixty-two patients were studied, all of whom received an intraocular infusion of approximately 200 to 300 mL of balanced salt solution with 0.5 mL of epinephrine 1:1000. There was no statistically significant change in blood pressure or heart rate during the time of epinephrine administration. Electrocardiogram monitoring during surgery showed no changes. We believe that dilute concentrations of epinephrine administered during extracapsular cataract extraction pose little threat of systemic toxicity. 相似文献
2.
Gérald Vanzetto Marc Janier Daniel Fagret Luc Cinotti Xavier André-Fouet Michel Comet Jacques Machecourt 《European journal of nuclear medicine and molecular imaging》1997,24(2):170-178
The best test presently available to ascertain residual viability within an infarct-related area involves the use of fluorine-18
fluorodeoxyglucose (FDG) to detect the persistence of some cellular metabolism. Rest reinjection of thallium-201 is a less
accurate alternative but is easy to perform. Iodinated fatty acids, which are used with standard gamma cameras, are proposed
as markers of cellular metabolism. This study was performed to assess the value of 16-iodo-3-methyl-hexadecanoic acid (MIHA)
as a marker of the residual cellular metabolism by comparison with FDG in patients with a recent myocardial infarction, and
to evaluate its contribution compared with the201Tl stress-redistribution-reinjection technique. Stress-redistribution-reinjection201T1 imaging, rest MIHA imaging and glucoseloaded FDG imaging were performed in 22 patients with recent myocardial infarction.
Out of the 628 myocardial segments obtained from the left ventricular analysis, 400 were hypoperfused (relative uptake <0.75
of maximum uptake on stress201T1 imaging), 177 of which were severely hypoperfused (relative uptake <0.50). Receiver operating characteristic (ROC) curves
for predicting metabolic myocardial viability with FDG were derived from the results in respect of (a)201T1 activity during exercise, redistribution and reinjection and (b) MIHA up-take, using the two FDG thresholds most commonly
considered to define metabolic viability (0.50 and 0.60). Analysis of the 400 hypoperfused segments demonstrated that201T1 reinjection was the most accurate test in predicting the presence of myocardial viability (area under the ROI curves=0.85
and 0.86 at the 0.50 and 0.60 FDG thresholds, respectively;P<0.05 vs other tests). The global predictive values of MIHA and201T1 reinjection were, respectively, 0.87 and 0.89 at the 0.50 FDG threshold (NS), and 0.82 and 0.87 at the 0.60 FDG threshold
(NS). When only the 177 severely hypoperfused segments were considered,201T1 reinjection remained the most accurate test (accuracy 0.84 at the 0.50 FDG threshold and 0.82 at the 0.60 FDG threshold),
while the accuracy of MIHA decreased significantly (0.78 at the 0.50 FDG threshold and 0.73 at the 0.60 FDG threshold,P<0.05 vs201T1 reinjection). In all circumstances, MIHA was less specific than201T1 reinjection for the detection of metabolic viability. In conclusion, in patients with recent myocardial infarction, MIHA
accurately detects the persistence of metabolic viability, but is not superior to201T1. 相似文献
3.
In patients with PG-dependent renal function, NSAID administration
constantly reduces GFR and RBF in a dose-dependent fashion. In this
situation, the risk of overt acute renal failure is high and should be
taken into proper account. In contrast, the incidence of NSAID-related
renal structural alterations appears to be very low, yet the absolute
number of patients may be significant considering the wide use of such
drugs. Concerning the antiproteinuric effect of NSAIDs, the unfavourable
ratio risk/benefit does not seem to support their indication in proteinuric
nephropathies. The development of PGHS-2 selective inhibitors is promising,
and may open new therapeutical strategies in the treatment of the
progression of renal disease.
相似文献
4.
Low day 3 luteinizing hormone values are predictive of reduced response to ovarian stimulation 总被引:7,自引:4,他引:3
Noci I; Biagiotti R; Maggi M; Ricci F; Cinotti A; Scarselli G 《Human reproduction (Oxford, England)》1998,13(3):531-534
The aim of the present work was to evaluate whether low day 3 luteinizing
hormone (LH) values in the presence of normal follicle stimulating hormone
(FSH) are predictive of poor response to ovarian stimulation. Two groups of
women undergoing ovarian stimulation and differing only in the day 3 LH
concentration (<3 mIU/ml, study group, n=30; >3 mIU/ml, control
group, n=45) were retrospectively analysed. Study group patients developed
a lower oestradiol peak (703+/-388 versus 955+/-400 ng/ml; P = 0.005) and a
lower number of follicles >15 mm diameter at the time of human chorionic
gonadotrophin (HCG) administration (2.6+/-1.3 versus 3.6+/-1.8; P=0.004)
than the control group. Conversely, a similar ratio of oestradiol:
follicles >15 mm diameter was observed (256+/-118 versus 269+/-93;
P=0.563). The number of follicles >10 mm at the time of HCG
administration appeared to be lower in the study group, but this difference
was not statistically significant (6+/-3.9 versus 7.8+/-4.3). Our data
indicate that day 3 LH values <3 mIU/ml are predictive of poor response
to ovarian stimulation.
相似文献
5.
B Croisile B Laurent D Michel D Le Bars L Cinotti F Mauguière 《Revue neurologique》1991,147(3):192-199
The authors report 3 cases of slowly progressive aphasia with different language disturbances: anomia, pure word deafness and Broca's aphasia. All patients were independent in daily life activities. Insight, judgement and overall behaviour were intact. There was no major disturbance of other cognitive functions, but psychometric tests showed mild deficits suggesting widespread involvement. CT scans and magnetic resonance imaging showed focal dilatation of the left sylvian fissure. A positron emission tomographic study showed left perisylvian hypometabolism. A review of the literature yielded an increasing number of cases of this degenerative syndrome affecting dominant hemisphere language areas. Our cases confirm the clinical heterogeneity of degenerative aphasia. Postmortem neuropathological examinations are rare and many causes are found: Pick's disease, Alzheimer's disease or aspecific gliosis. 相似文献
6.
An indicator of operating technique (phantom) is very useful for quality control in diagnostic radiology. We tested experimentally that the "Random Phantom" is the most suitable between those commercially available for xeromammography. In fact this indicator points out image quality alterations caused even by very small variations of the physical parameters affecting image quality. We did not test the phantoms for mammographic technique but we believe that the "Random" is the most suitable in this field too. 相似文献
7.
Cinotti WR Saporito RA Feldman CA Mardirossian G DeCastro J 《Journal of dental education》1999,63(12):969-975
The dental school plans to incorporate CODE into the curriculum so that more students have community-based dental educational experiences. Future plans also include increasing standardization of reports, clinical and administrative procedures, resources, and processes across the sites in order to lower managerial overhead. This process will be aided by further enhancement of computerized information systems and electronic links. The major lesson learned is that new extramural programs can be created and sustained by pooling school resources with those from the private and public sectors. Funding sources and opportunities available to one party alone are insufficient. While one-time funding was used to build and furnish the NJDS extramural sites, the clinics were established only after business plans demonstrated the availability of funds to sustain their operations. The Statewide Network of Community Oral Health Care and CODE models are still evolving, but they are replicable not only in dental education but in other types of health services. The details of the partnerships and funding streams will vary from site to site, but through outreach and careful negotiation with potential partners and detailed contracts, the community service and educational missions of a health professions school can have a successful outcome. 相似文献
8.
Renal blood flow measurement by positron emission tomography using 15O-labeled water 总被引:2,自引:0,他引:2
Juillard L Janier MF Fouque D Lionnet M Le Bars D Cinotti L Barthez P Gharib C Laville M 《Kidney international》2000,57(6):2511-2518
BACKGROUND: Only few noninvasive methods have the potential to quantitate renal blood flow (RBF) in humans. Positron emission tomography (PET) is a clinical imaging method that can be used to measure the tissue blood flow noninvasively. The purpose of this study was to validate PET measurement of RBF using 15O-labeled water (H215O), a tracer that allows repeated measurements at short time intervals. METHODS: RBF was measured in six pigs by PET and by radioactive microspheres (MS). Three measurements were performed in each pig at baseline (BL), during vascular expansion and dopamine infusion (DA; 20 microg. kg-1. min-1 intravenously), and during angiotensin II (Ang II) infusion (50 ng. kg-1. min-1 intravenously). RBF was estimated from aortic and renal tracer kinetics using a model adapted from the blood flow model described by Kety and Smith. RESULTS: PET and MS values correlated strongly (y = 0.79x + 42, r = 0.93, P < 0.0001) over the RBF range from 100 to 500 mL. min-1. 100 g-1. Pharmacologically induced changes were significant and were measured equally well by PET and MS: 38 and 39%, respectively, below BL (P < 0.005 and P < 0.05) under Ang II, and 47 and 48%, respectively, above BL (P < 0.005 and P < 0.01) under DA. A Bland and Altman representation showed a low average difference of -17 +/- 45 mL. min-1. 100 g-1 (mean +/- SD). CONCLUSION: To our knowledge, this study provides the first validation of RBF measurement by PET using H215O over a large range of RBF values (100 to 500 mL. min-1. 100 g-1), which correspond to RBF values in both healthy subjects and in patients suffering from chronic renal failure. 相似文献
9.
10.
Gianluca Cinotti Pasquale Sessa Giovanni Ragusa Francesca Romana Ripani Roberto Postacchini Raffaele Masciangelo Giuseppe Giannicola 《Clinical anatomy (New York, N.Y.)》2013,26(7):883-892
We analyzed the magnetic resonance studies of the knee in 80 subjects, 45 men and 35 women with a mean age of 38.9 years, who showed no pathological condition of the joint. Using an imaging visualization software, the sagittal longitudinal axis of the tibia was identified. The angle between this axis and a line tangent to the bone profile of the tibial plateau (bone slope) and to the superior border of the menisci (meniscal slope) were calculated. Thickness of anterior and posterior portion of menisci and underlying cartilage were also measured. The bone slope averaged 8° and 7.7° on the medial and lateral sides, respectively. The mean meniscal slope was 4.1° and 3.3° on the medial and lateral sides, respectively, with a significant difference compared with the bone slope. Menisci and underlying cartilage were significantly thicker in their posterior than their anterior portion (7.6 and 5.2 mm, respectively, in the medial compartment; 8.6 and 5.2 mm, respectively, in the lateral compartment). The presence of cartilage and menisci implies a significant decrease in the posterior tibial slope. In the lateral compartment, the greater the bone slope, the larger the difference between bone and meniscal slope, which means that a marked posterior tilt of the lateral tibial plateau is decreased by the cartilage and meniscus. These findings should be taken into account in planning surgical procedures which affect the slope of the articular tibial surface. Clin. Anat. 26:883–892, 2013. © 2012 Wiley Periodicals, Inc. 相似文献