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排序方式: 共有404条查询结果,搜索用时 15 毫秒
1.
Sedigheh Sadat Tavafian Ahmadreza Jamshidi Kazem Mohammad Ali Montazeri 《BMC musculoskeletal disorders》2007,8(1):21
Background
Different interventions can reduce the burden of the chronic low back pain. One example is the use of a 'Back School Programme'. This is a brief therapy that uses a health education method to empower participants through a procedure of assessment, education and skill development. This study aimed to evaluate to what extent the programme could improve quality of life in those who suffer from the condition. 相似文献2.
Delmaghani S Aghaie A Compain-Nouaille S Ataie A Lemainque A Zeinali S Lathrop M Weil D Petit C 《European journal of human genetics : EJHG》2003,11(10):816-818
We report on a novel localization for a recessive form of deafness (DFNB), by linkage analysis in an Iranian consanguineous family. Affected individuals suffer from prelingual profound sensorineural hearing loss. Genome-wide analysis led to the characterization of a new locus, DFNB40, which maps to an approximately 9 Mb interval between markers D22S427 and D22S1144 at chromosome 22q11.21-12.1. Maximum lod score of 3.09 was obtained with D22S1174. Since the Bronx waltzer (bv) mouse mutant, characterized by waltzing behavior, deafness, and degeneration of cochlear inner hair cells, has been mapped to the syntenic region on murine chromosome 5, we suggest that DFNB40 and bv may result from orthologous gene defects. 相似文献
3.
Mitochondrial DNA and Y-Chromosome Variation in the Caucasus 总被引:7,自引:3,他引:7
I. Nasidze E. Y. S. Ling D. Quinque I. Dupanloup R. Cordaux S. Rychkov O. Naumova O. Zhukova N. Sarraf-Zadegan G. A. Naderi S. Asgary S. Sardas D. D. Farhud T. Sarkisian C. Asadov A. Kerimov M. Stoneking 《Annals of human genetics》2004,68(3):205-221
We have analyzed mtDNA HVI sequences and Y chromosome haplogroups based on 11 binary markers in 371 individuals, from 11 populations in the Caucasus and the neighbouring countries of Turkey and Iran. Y chromosome haplogroup diversity in the Caucasus was almost as high as in Central Asia and the Near East, and significantly higher than in Europe. More than 27% of the variance in Y‐haplogroups can be attributed to differences between populations, whereas mtDNA showed much lower heterogeneity between populations (less then 5%), suggesting a strong influence of patrilocal social structure. Several groups from the highland region of the Caucasus exhibited low diversity and high differentiation for either or both genetic systems, reflecting enhanced genetic drift in these small, isolated populations. Overall, the Caucasus groups showed greater similarity with West Asian than with European groups for both genetic systems, although this similarity was much more pronounced for the Y chromosome than for mtDNA, suggesting that male‐mediated migrations from West Asia have influenced the genetic structure of Caucasus populations. 相似文献
4.
Sahar rajabzadeh Karizi Fatemeh Armanmehr Hamideh Ghodrati Azadi Hojjat Shadman Zahroodi AmirAli Moodi Ghalibaf Bibi Sedigheh Fazly Bazzaz Mohammadreza Abbaspour Javad Boskabadi Saeid Eslami Zhila Taherzadeh 《Phytotherapy research : PTR》2023,37(4):1435-1448
The efficacy of spirulina platensis (S. platensis) as an add-on therapy to metformin and its effect on atherogenic keys in patients with uncontrolled Type 2 Diabetes Mellitus (T2DM) was evaluated. Sixty patients were randomly assigned to S. platensis (2 g/day) or placebo group for three months while continuing metformin as their usual treatment. The efficacy of S. platensis was determined using the pre- and post-intervention HbA1c levels (primary outcome) as well as tracking FBS and lipid profiles levels (TC, LDL-C, TG, and HDL-C) as secondary outcomes at the different treatment time points (0,30,60,90 days). During the three–month intervention period, supplementation with S. platensis resulted in a significant lowering of HbA1c (↓1.43, p < 0.001) and FBS (↓ 24.94 mg/dL, p < 001) levels. Mean TG in the intervention group was found to be significantly lower in the intervention group than in controls (p < 0.001). Total cholesterol (TC) and its fraction, LDL-C, exhibited a fall (↓41.36 mg/dL and ↓38.4 mg/dL, respectively; p < 0.001) coupled with a marginal increase in the level of HDL-C (↑3 mg/dL; p < 0.001). Add-on therapy with S. platensis was superior to metformin regarding long-term glucose regulation and controlling blood glucose levels of subjects with T2DM. Also, as a functional supplement, S. platensis has a beneficial effect on atherogenic keys (TG and HDL-C) with no adverse events. 相似文献
5.
Anti-oxidant effect of flavonoids on hemoglobin glycosylation 总被引:7,自引:0,他引:7
Asgary S Naderi G Sarrafzadegan N Ghassemi N Boshtam M Rafie M Arefian A 《Pharmaceutica acta Helvetiae》1999,73(5):223-226
A high glucose concentration has been found to lead to the glycosylation of amino groups of lysine residue in proteins. The addition of reducing agent not only prevents this reaction but also reverses it. On the other hand, flavonoids which found in plant sources have antioxidant properties. Since the glycosylation of protein is an oxidation reaction, therefore, antioxidants should be able to prevent this reaction. In this study, the best concentration and time to incubate glucose with hemoglobin was investigated. Then the glycosylation degree of hemoglobin in the presence of flavonoids and their absence was measured by means of a colorimetric method. Different concentration of flavonoids (Quercetin, Rutin, Kaempferol) were used. The preventing effect on hemoglobin glycosylation by the three concentrations; 0.5, 5, 10 micrograms/ml was estimated as follows: for Rutin; 11%, 27%, 42%, Quercetin; 3%, 37%, 52%, Kaempferol; 10%, 12%, 15% respectively. So, the in vivo effect should be investigated and then plants that containing flavonoids can be utilized to prevent or treat complication of diabetes. 相似文献
6.
Constituents of the essential oil of Achillea wilhelmsii L. growing wild in Kerman-Iran were studied by TLC, GC, and GC/MS methods. The main components of the monoterpene fraction of the oil were camphor, borneol, linalool, 1,8-cineole, chrysanthenol acetate, and carvacrol. The percentage of the identified sesquiterpenoid components was relatively high and constituted 29% of the oil. 相似文献
7.
Maryam Shojaeifard MD Sedigheh Saedi MD Alireza Alizadeh Ghavidel MD Mohammad Reza Karimlu MD Mohammad Kasaei MD Hamid Reza Pouraliakbar MD Kambiz Mozaffari MD 《Echocardiography (Mount Kisco, N.Y.)》2020,37(3):462-464
Primary tumors of the heart are rare with a reported incidence of about 0.002% to 0.3% at autopsy. A cardiac hemangioma is a form of benign primary cardiac tumor that often presents with atypical clinical symptoms. Hemangiomas are generally isolated lesions. Here, we report a patient with previous hepatic hemangioma who later was found to have a large coexistent cardiac hemangioma presenting with cardiac compressive symptoms. 相似文献
8.
9.
Ferdos Zaman Sedigheh Nouhjah Hajieh Shahbazian Nahid Shahbazian Seyed Mahmoud Latifi Alireza Jahanshahi 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(5):721-725
Aims
Early identification of at-risk groups is an important step in preventing gestational diabetes and its subsequent side effects. This study aimed to evaluate the risk factors of gestational diabetes based on the International Association of Diabetes and Pregnancy Study Groups criteria in Ahvaz.Material and Methods
In a cross-sectional case control study, 520 pregnant women involving life after gestational diabetes Ahvaz cohort study (LAGAs) were investigated for risk factors of gestational diabetes mellitus.Result
The prevalence of overweight and obesity were 40% and25.8% in the GMD group and in 35.8% and 16.2% in the control group respectively (p?=?0.002). According to NCEP-ATP III criteria, 16.9% of women with GDM and 6.9% of mothers in the control group had metabolic syndrome in first visit of pregnancy (p?<?0.001. Logistic regression showed that there is a significant relationship between maternal age[OR?=?1.05(95% CI, 1.01–1.10)] (p?=?0.01), previous GDM [OR?=?5.60(95% CI, 2.21–14.18)] (p?=?0.001), positive family history of diabetes[OR?=?1.86(95% CI, 1.19–2.94)] (p?=?0.006), pre-pregnancy BMI [OR?=?1.05(95% CI, 1.007–1.11)] (p?=?0.04) and metabolic syndrome in first visit of pregnancy[OR?=?2.34 (95% CI, 1.038–5.30)] (p?=?0.04) with GDM.Conclusion
Factors including maternal age, previous GDM, family history of diabetes, pre-pregnancy BMI reported in previous studies around the world. A significant association between metabolic syndrome in the first visit of pregnancy and GDM is novel finding of this study. Therefore screening of pre-pregnancy metabolic syndrome in women at risk of gestational diabetes is recommended. 相似文献10.