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目的:研究宁舒洗剂的体外抗菌作用特点。方法:80株细菌全部近期临床分离所得,其中G^ 菌34株,G^-菌46株;采用试管内药液二倍稀释法,测定宁舒洗剂的NIC、MBC,对于产ESBLS的大肠杆菌(耐药菌株)与不产ESBLS的普通大肠杆菌的MIC和MBC进行比较,另外,观察了细菌接种量和药物PH值分别对MIC、MBC的影响。结果:①宁舒洗剂对所有试验菌株均有抑菌作用,对G^ 的作用较好,其MIC50为1:32,而G^-菌的MIC50为1:8。②对试验菌均具有杀菌作用,仍对G^ 的作用较好,其MBC50为1:32,而G^菌的MBC50为1:4。每种细菌的MBC50与MIC50和MIC90等值均十分接近甚至相等。③对于产ESBLS大肠杆菌的抗菌作用与普通大肠杆菌相同,MIC50、MIC90、MBC50、MBC90均为1:4。④细菌接种量为10^2cfu/ml的效价均高于10^4cfu/ml。⑤药物PH值为8.0时药物的效价高于PH6.0。结论:宁舒洗剂具有体外抑菌和杀菌作用,对G^菌的作用较好,对产ESBLS的大肠杆菌也具有抗菌作用。 相似文献
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温经活血对实验损伤性动脉硬化性闭塞症家兔血液流变学的影响 总被引:3,自引:0,他引:3
动脉硬化性闭塞症(ASO)系全身动脉硬化(AS)之局部表现,临床以下肢多见,病至晚期会出现广泛高位坏疽;此时,即便截肢,创口亦难愈合.本病致残率极高,死亡率占周围血管病之首位[1].目前,其发病率呈增长趋势,而国内外尚无疗效肯定的西药.温脉通合剂(简称WMT)以温经活血为法,系全国著名中医外科周围血管病专家陈淑长教授积数十年经验,针对ASO创制的临床疗效肯定之中药制剂.本研究通过观察WMT全方对ASO家兔模型诸项血液流变学变异指标的影响,了解温经活血对实验损伤性ASO家兔血液流变学之影响. 相似文献
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目的:为湖南省生物医药科技创新和企业竞争提供服务以及生物医药产业发展的专利战略制定提供依据。方法:利用PatentEX专利管理软件数据库采集湖南省生物医药专利数据,采用专利计量和统计分析方法对专利数据处理。结果:湖南省专利申请量呈逐年上升趋势,但专利失效率较高;生物医药专利技术发展进入成熟期,专利申请量集中于几个重要的IPC分类中。结论:湖南省生物医药产业以传统技术为主,现代生物技术发展相对落后;生物医药发明专利申请数量较大,但整体质量偏低;大部分生物医药企业缺乏竞争意识。应加强现代生物技术开发,提高生物医药专利申请质量,增强生物医药企业的专利竞争意识,加强专利合作研发,重点扶植生物医药企业发展。 相似文献
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The effects of Chinese medicines on micro-circulation and blood flow velocity in arteries of the lowerlimbs were observed in 33 patients with arteriosclerotic obliteration(ASO).The results showed that theintegral values of micro-circulation after treatment were obviously higher than those before treatment(P<0.05 or P<0.01).Blood flow velocity in arteries of the lower limbs determined with the color Dopplerultrasound detecting method after treatment were also obviously higher than those before treatment(P<0.05 or P<0.01).In tbis series of 33 ASO patients,the markedly effective rate was 36.36%,and thetotal effective rate was 63.64%.The observation indicates that the recipe prescribed according to theprinciple of supplementing qi and activating blood circulation can effectively improve micro-circulation inASO patients,and accelerate blood flow in arteries of the lower limbs. 相似文献
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Ningshu Xiji (宁舒洗剂), a compound TCM Lotion developed by Prof. Chen Shuchang of the Oriental Hospital, has the effects of clearing away heat and the toxic materials, removing dampness by diuresis and promoting blood circulation. With Li Zhi Cao (荔枝草 Herba Salviae Plebeiae), Tu Fu Ling (土茯苓Rhizoma Smilacis Glabrae) , Jin Yin Hua (金银花Flos Lonicerae), and Puxiao (朴硝 Mirabilitum) as main ingredients, the lotion has the non-toxic components and achieves very satisfactory therapeutic effects for the ecthyma characterized by downward flow of damp-heat. From August 2002 to June 2003, Ningshu Xiji was used to apply to the surface of wounds of 34 ecthyma patients based on the routine treatment. The effects of Ningshu Xiji on venous ulcers of the limbs is reported as follows: 相似文献
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