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Eight hundred and ten pedigree members of 110 patients with Graves' disease were studied. In 700 first-egree relatives, inquiry of medical history, physical examination (including eyes, thyroid, heart rate, etc), thyroid function tests (serum T3, T4 and TSH levels), determinations of thyroglobulin antibodies (TgAb) and thyroid microsomal antibodies (TmAb) were performed. For male (female) probands, the incidence of Graves' disease in male (female) first-degree relatives were investigated and their serum TgAb and TmAb were analysed. The incidence of these two kinds of autoantibodies in the male (female) first-egree relatives of familial and nonfamilial Graves' disease were analysed. Eighteen persons with positive TgAb and TmAb from 5 pedigrees had been followed up one year after initial determinations. Our results suggest that the positive rates of TgAb and TmAb in the first-egree relatives of Graves' disease were coincident with the incidence of Graves' disease, and the positive results of TgAb and TmAb 相似文献
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用化学发光法检测粒细胞吞噬功能具有灵敏、准确、快速等优点。用我校同位素实验室LS3801型液体闪烁分析仪,全部使用国产试剂,建立了分离的中性粒细胞化学发光测定法,并对影响因素作了初步观察和探讨。实验表明,此法既可用于中性粒细胞吞噬杀菌功能机理研究,亦可用于临床监测。对糖尿病人粒细胞功能化学发光测定结果,显示了此法应用的潜力。 相似文献
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无黄疸型传染性肝炎,近年来随着党对人民群众身体健康的关怀,随着临床医师的注意和新检验技术的开展,其发病数字是逐渐增加。但由于无黄疸型传染性肝炎病理改变较轻,自觉症状不严重,往往造成胎误诊断。至目前为止,特异诊断方法很少,这对肝炎的防治带来不少困难。为了探讨其临床诊断方法,现将我院新近门诊确诊的无黄疸型肝炎患者30例,加以分析,以供参考。一、一般分析30例均系门诊病人,年龄15—45岁,平均年龄为30岁;其中男性26人,女性4人;机关干部23人,医务人员2名,农民2人,家庭主妇3人。二、诊断依据1.密切接触史;2.典型症状;3.肝脏肿大或伴有脾脏肿大且有明显压痛及叩打痛;4.肝功能检查异常;5.超声波显示典型肝炎波型;上述五项中有任何三项明显阳性者,或在2、3、4、5项中具有任何二项明显阳性者,均确诊为肝炎。三、临床分析1.无黄疸型传染性肝炎大多起病缓和,没有严重的自觉症状,且不能告知一个确切的发病日期,因此潜伏期无法统计。临床症状可表现为多种多样,主要为消化道机能紊乱、消瘦、乏力等。如表一所示:腹胀73.3%,食欲不振36.6%,肝区痛70%,消瘦60%, 相似文献
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糖尿病病人脂代谢紊乱是导致伴发冠心病的重要因素。近年来国内外的一些研究发现,冠心病病人及NIDDM病人血清中HDL-C,HDL_2-C、HDL_3-C均降低,其中以HDL_2-C下降明显;低密度脂蛋白胆固醇(LDL-C)和ApoB则增高。由于脂蛋白胆固醇受糖尿病类型、性别、年龄、月经周期的影响表现出很大差异,本文选择了一组女性绝经后NIDDM病人与相应正常人比较,以了解该组病人胆固醇代谢紊乱与冠心病的关系,并探讨了测定血清脂蛋白胆固醇以及ApoB对评估该组NIDDM病人冠心病的价值。 相似文献
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