慢性病毒性肝炎胆囊声像异常与肝组织炎症坏死程度的关系

目的：探讨慢性病毒性肝炎胆囊声像异常与肝组织炎症程度的关系。方法：分析了１１２例慢性肝炎患胆囊壁厚度,光滑度,胆囊大小异常,合并胆囊结石及息肉的发生率,并与肝组织病理炎症坏死程度分级进行比较及相关分析。结果：胆囊声像异常总发生率为５７．１４％,胆囊壁厚在轻、中、重度慢性肝炎相互间比较差异均有显性,与肝脏炎症坏死程度呈显性正相关（ｒ＝０．６７,Ｐ〈０．０００１）。胆囊壁不光滑及胆囊大小异常发生     

肝储备功能定量评估的影像学研究进展

综述肝储备功能定量评估的影像学研究进展。准确评估肝脏储备功能,有利于降低肝脏部分切除术后并发症或肝移植术后移植物原发性无功能和早期移植物功能不良的发生率。     

声学造影在肝癌诊断中的应用及其进展

肝癌由肝动脉和门静脉双重供血 ,其中以肝动脉供血为主 ,约占 90 %以上[1 3 ] ,表现为肝内血管扩张 ,移位变形 ,血管异常增生 ,血管包绕 ,肿瘤新生血管及动静脉瘘形成 ,这是超声造影诊断肝癌的组织病理学基础。所以 ,真实全面地了解肿瘤内部及周边部的血管分布、血流性质 ,对肝     

近似人病理生理过程动物脂肪肝模型的综合建立方法

Objective To establish animal model of fatty liver similar with human pathophysiology used for the study of imaging quantitative diagnosis or verification of medicine curative effect. Methods Forty-five New Zealand white rabbits were used in this study. They were divided randomly into five groups : 10 rabbits in normal control group, 10 rabbits in experiment group 1,10 rabbits in experiment group 2,10 rabbits in experi-ment group 3,and remaining 5 rabbits were in a supplement group. Rabbits in normal control group were given free access to normal food and water for 9 weeks. Rabbits in the experimental groups were fed a high-fat and high-sucrose diet for 3,6,and 12 weeks,respectively. Rabbits in the supplement group were fed the same diet as the experimental groups. Liver specimen stained with HE and Sudan Ⅳ was examined histological. Results The success rate of hepatic steatotie models was 87 % (39 of 45 ) ;mortality was 13 % (6 of 45 ). There were 10 nor-mal livers, 10 mildly fatty livers, 9 moderately fatty livers, and 10 severely fatty livers in results (stained with HE), and the rate of conforming to Sudan Ⅳ was 75%. Conclusion The animal model of fatty liver with differ-ent severity can be established by being fed a high fat, high sucrose and alcohol diet.     

近似人病理生理过程动物脂肪肝模型的综合建立方法

Objective To establish animal model of fatty liver similar with human pathophysiology used for the study of imaging quantitative diagnosis or verification of medicine curative effect. Methods Forty-five New Zealand white rabbits were used in this study. They were divided randomly into five groups : 10 rabbits in normal control group, 10 rabbits in experiment group 1,10 rabbits in experiment group 2,10 rabbits in experi-ment group 3,and remaining 5 rabbits were in a supplement group. Rabbits in normal control group were given free access to normal food and water for 9 weeks. Rabbits in the experimental groups were fed a high-fat and high-sucrose diet for 3,6,and 12 weeks,respectively. Rabbits in the supplement group were fed the same diet as the experimental groups. Liver specimen stained with HE and Sudan Ⅳ was examined histological. Results The success rate of hepatic steatotie models was 87 % (39 of 45 ) ;mortality was 13 % (6 of 45 ). There were 10 nor-mal livers, 10 mildly fatty livers, 9 moderately fatty livers, and 10 severely fatty livers in results (stained with HE), and the rate of conforming to Sudan Ⅳ was 75%. Conclusion The animal model of fatty liver with differ-ent severity can be established by being fed a high fat, high sucrose and alcohol diet.     

超声评估活体肝移植供体肝静脉临床价值的研究

目的 探讨超声在活体肝移植供肝肝静脉评估中的临床价值.方法 回顾性分析17例活体肝移植供体,术前均行超声及CT检查,观测管径大于5mm中肝静脉(MHV)属支及右后下静脉(IRHV)情况.结果 超声发现管径大于5mm MHV属支及IRHV的数目分别为8(S4)、7(S5)、5(S8)、8(IRHV),CT为8(S4)、7(S5)、9(S8)、14 (IRHV),两者的一致率为73.7％ (28/38),将MHVS8属支和IRHV的超声管径标准缩小至4mm再次统计,数目为8(S8)、14 (IRHV),与CT的一致率为97.4％ (37/38).结论 超声可用于评价活体肝移植供肝肝静脉情况.     

腔内超声造影技术在引流管定位中的应用价值

目的 探讨腔内超声造影技术对常规超声下显示不清的引流管进行定位的价值.方法 26例患者共计32条留置的引流管引流不畅,常规超声无法清晰显示全程,经引流管注入稀释后的超声造影剂SonoVue对引流管进行观察,评价超声造影技术对引流管管体和引流管末端的显示能力,所需的检出时间,并判断有无脱管.结果 常规超声检查对引流管管体...     

"以临床应用为导向"的住院医师心电图实践教学效果探析

目的探讨住院医师规范化培训(下文简称住培)中"以临床应用为导向"的心电图实践教学效果。方法本研究采用试验对照和问卷调查方法。选取2019年参加中山大学附属第五医院心电图课程的96名住培学员作为研究对象。将参加春季课程的49名住培学员设为对照组,采用传统教学方法;参加秋季课程的47名住培学员设为试验组,采用"以临床应用为导向"的实践教学方法。分析比较两组学员的课程考核成绩和对课程满意度的问卷调查结果。结果试验组学员过程考核成绩(86.16±20.21)分高于对照组学员的(71.49±23.86)分,试验组学员期末考核成绩(74.00±9.33)分高于对照组学员的(66.53±8.29)分,差异均具有统计学意义(均P<0.05)。对于授课内容和方法可以运用到临床工作中,试验组学员的满意度95.7%(45/47)高于对照组学员的83.7%(41/49);对于课程形式有助于增加学习心电图的兴趣和投入度,试验组学员的满意度87.2%(41/47)高于对照组学员的51.0%(25/49),差异均具有统计学意义(均P<0.05)。结论"以临床应用为导向"的心电图实践教学,有助于提高住培学员的学习成绩和对课程的满意度。     

多普勒超声评价丹参对硬化门静脉血流动力学的影响

目的 通过多普勒超声检测门静脉系统血流,评价丹参对肝硬化患者门静脉血流动力学影响,并探讨多普勒超声的应用价值。方法 将肝硬化患者分为丹参治疗组及对照组,分别于治疗前、治疗2周后及治疗8－12周后用彩色多普勒超声检测门静脉及脾静脉的管径、最大流速及血流量,比较治疗前后血流参数的变化。结果 丹参治疗2周及8－12周后门静脉血流速度持续加快,门静脉管径、脾静脉管径及血流量持续下,差异有显著性,而门静脉血流量无明显变化。对照组各项血流参数无显著性变化。结论 丹参可降低门脉阻力,加快门静脉血流速度,同时降低脾静脉血流量,达到降低门脉压的效果。多普勒超声检测门脉系统血流有助于评价药物治疗门脉高压的效果。     

离体猪肝三维超声胆管造影的实验研究

目的 探讨三维超声胆管造影技术显示肝内胆管的可行性.方法 对5个离体猪肝不同肝叶的胆管分别进行插管,经插管注入1:20稀释的SonoVue超声造影剂后进行三维超声造影检查,分别评价可分辨最高胆管分支级别和图像质量,并与X线胆道造影作比较,评价其胆管树形态拟合度.结果 在5个离体猪肝中成功插管14个分叶,最高可显示至第3级分支,最高显示级别为第3、2、1级分支的比例依次为42.9%(6/14)、42.9%(6/14)、14.2%(2/14);图像质量优、中、差的比例依次为21.4%(3/14)、57.2%(8/14)、21.4%(3/14);与X线胆道造影比较,图像拟合度优、中、差的比例依次为42.9%(6/14)、42.9%(6/14)、14.2%(2/14).结论 三维超声胆管造影技术可能是一种显示胆管树解剖结构的全新影像学方法.