中医药治法再闪新亮点（八）

沈自尹院士指出，清热解毒药本身不是激素或细胞因子，也非单抗阻断剂或专一的酶抑制剂，却是通过对复杂的细胞因子网络进行精密协调．使得前炎性细胞因子不至于过度分泌，从而改善炎症与组织损害。这可能也是清热解毒药对付SAPS的高招。很多疾病包括很常见的中风、心肌梗死、动脉粥样硬化等，现代很多报道证实这些疾病与感染病毒有关系，还有免疫类疾病，如类风湿、强直性脊柱炎、干燥病、慢性肾炎、膜性肾病，使用清热解毒类中药都有一定的效果，这可能是近年来清热解毒倍受重视的原因之一。     

经颅磁刺激器设计及对毒品依赖者脑功能变化的评价

对经颅磁刺激进行了磁场强度分布的测试,分为3个方面,即分别对经颅磁刺激轴向和径向磁场强度的分布及在有效刺激区内的磁场最强圆周上磁场强度分布矢量值进行测试.在对毒品依赖者的康复实验中,将经颅磁刺激具体应用到对毒品依赖者进行治疗的实验测试中.磁刺激前,要记录毒品依赖者的脑电图,同时给患者不同的毒品图片进行视觉刺激.随后进行1个疗程的经颅磁刺激.之后,再用与第1次相同的视觉刺激序列,给患者看与经颅磁刺激治疗前相同的毒品图片,并记录患者的脑电数据,将前后2次的脑电数据经过一定步骤的处理后,将得出的刺激前后的N270波幅和潜伏期数据进行比较分析.经颅磁刺激刺激后毒品依赖者的N270振幅会有明显的降低,潜伏期会缩短,并且吸毒患者异常脑区的脑功能有所变化.毒品依赖者大部分存在差片的电极位于人的大脑的额叶区、顺叶区、顶叶和枕叶区,因此可以预测其大脑的额叶、颞叶、顶叶和枕叶可能受到海洛因的损害,该区域脑功能异于正常人.经过1个疗程经颅磁刺激刺激后,毒品依赖者的N270振幅和潜伏期都更接近正常人.因此,经颅磁刺激治疗对于海洛因依赖者有一定的疗效.     

打造新时期过硬监管队伍

新时期的食品药品监管工作，对执法队伍的要求越来越高，也越来越严格。树立新时期监管新形象，打造过硬执法队伍，笔者认为，应该在树立以下五个方而形象，提高五个方面能力上入手，切实把基层执法队伍建设工作推上一个新台阶。     

漫话珍珠

中国古代宫廷一直将珍珠粉视为美容护肤佳品。相传,珍珠粉是使西施、杨贵妃等美女保有如玉肌肤的秘密武器。据说慈禧太后每隔十天就要服用一银匙珍珠粉,数十年从不间断。     

儿科专家自摘招牌

儿科名医徐小圃的幼儿在一年夏季患了伤寒病.徐小圃亲自为之诊治,但病情加重,几濒于危,全家焦急,徐小圃亦感棘手.当时,家属及诸亲好友,均向徐小圃建议,恳请其医友祝味菊先生会诊一决.徐小圃慨然叹曰:"我与祝君虽属莫逆之交,但学术观点不同,他擅温阳,人称‘祝附子’.今孩子患的是热病,若祝君来诊,无非温药而已,此明知其‘抱薪救火’,我孰忍目睹其自焚耶?"又过了几天,患儿几将奄奄一息,亲友竭力敦促,与其束手待毙,何妨一试究竟.徐小圃无奈之下,恳请祝味菊来治病.     

Study of repeated nerve stimulation in myasthenia gravis

AMI：To investigate normal value range of low-frequent repeated nerve stimulation (RNS): whether different low-frequent stimulation and different muscles have different normal value rang.METHODS:Low-frequent(3c/s and 5c/s) RNS of 30 healthy people and 27 myasthenia gravis (MG) patients were rest. RESULTS:Superior limit of amplitude of wave attenuation value of low-frequent RNS(x^-&;#177;2.5s) of different muscles (orbicularis oculi muscle, deltoid muscle and abductor muscle of little finger) of healthy people was 5.45%-7.55%. According to our normal value standard, RNS positive rate of MG group was 85%; according to the current criteria (amplitude of wave attenuation value&;gt;10%), positive rate of MG group was 70%, there was no apparent difference in RNS positive rate (P&;gt;0.1). Some labs adopted the criteria that amplitude of wave attenuation value&;gt;15%, according to this criteria, positive rate of MG group was 51%. Compared with positive rate (85%) obtained according to our criteria, there was apparent difference(P&;lt;0.01).CONCLUSION:Each labs should establish their own normal value standard according to difference muscle and different frequent. If adopt universal standard,amplitude of wave attenuation value 8% or 10% was suggested.     

Electrophsiological study in the prognosis of Bell palsy

AIM:To estimate the prognosis of Bell palsy,METHODS:Blink relex (BR),electromyography(EMG),motor latency(ML) and amplitude (AMP) of facial nerve were performed in 42 patients with Bell‘‘‘‘s palsy.The patients were followed about half a year.RESULTS:(1) When 1 of the 3R waves related with the ill side existed or appeared in 3 weeks after onset,97% patients could recover completely.THe recovery time was realted to the time of the occurrence of R wave.(2) When 1 of the 3R waves appeared in the 4th week.60% patients could recover completely,When none of the 3 wasves appeared after the 4th week,100% patients could not recover completely.EMG showed spontaneous activities in 3 of the 6 patients in the 4th week.(3) Motor latency and amplitude of facial nerve were examined when the illness stopped developing.All patients had normal lalencies,5 patinets‘‘‘‘ amplitudes reduced more than 90%.3 of the 5 patients did not appear the related R waves after the 4th week.CONCLUSION:BR might provide the early sign of good prognosis of Bell‘‘‘‘s palsy ,BR together with EMG and ML and AMP of facial nerve might provide the later sign of poor prognosis.     

电生理检测对贝耳麻痹患者的预后评估

INTRODUCTIONBellpalsyisoneofthemostcommondiseasesinneurologicalde－partment．HowtopredicttheprognosisofBellpalsyiswhatdoctorsandpatientsareconcernedabout．MATERIALSANDMETHODSMaterialsClinicalmaterialswerecollectedfromFebruary１９９６toDecember２０００．４２caseswereselectedfrom１０６casesofBellpalsywhosemanifestationsandelectrophysiologicaltestwerefollowedupcontinuously．Patientssex：２２menand２０women；Agerang：１８－７４yearsold，averageage：３８yearsold；Thefirsttestingtimew…     

血流动力学优化在人工心脏设计中的应用

心力衰竭(心衰)是一种高危险、高发病率的心血管疾病。人工心脏作为心力衰竭的有效治疗手段正逐步应用于临床治疗中。血液相容性是人工心脏的重要参数或者指标,而如何通过血流动力学设计与体外溶血实验对其进行评价是业内的研究热点。本文首先对人工心脏血流动力学优化以及体外溶血评价方面的研究进展进行综述,之后介绍团队在相关领域的研究成果与进展。本文中所优化的血泵,血流动力学性能满足使用需求,体外溶血实验获得的溶血指数小于0.1 g/100 L,有较好的体外溶血性能。本文所述的优化方法适合于大部分血泵的开发工作,能够为相关研究工作提供借鉴。