全文获取类型
收费全文 | 6829篇 |
免费 | 646篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 56篇 |
儿科学 | 270篇 |
妇产科学 | 146篇 |
基础医学 | 924篇 |
口腔科学 | 122篇 |
临床医学 | 870篇 |
内科学 | 1254篇 |
皮肤病学 | 78篇 |
神经病学 | 620篇 |
特种医学 | 221篇 |
外国民族医学 | 1篇 |
外科学 | 831篇 |
综合类 | 152篇 |
一般理论 | 6篇 |
预防医学 | 842篇 |
眼科学 | 103篇 |
药学 | 428篇 |
1篇 | |
中国医学 | 6篇 |
肿瘤学 | 563篇 |
出版年
2023年 | 63篇 |
2022年 | 107篇 |
2021年 | 200篇 |
2020年 | 116篇 |
2019年 | 194篇 |
2018年 | 209篇 |
2017年 | 179篇 |
2016年 | 149篇 |
2015年 | 169篇 |
2014年 | 208篇 |
2013年 | 344篇 |
2012年 | 430篇 |
2011年 | 485篇 |
2010年 | 253篇 |
2009年 | 173篇 |
2008年 | 377篇 |
2007年 | 312篇 |
2006年 | 259篇 |
2005年 | 257篇 |
2004年 | 273篇 |
2003年 | 223篇 |
2002年 | 219篇 |
2001年 | 163篇 |
2000年 | 141篇 |
1999年 | 139篇 |
1998年 | 47篇 |
1997年 | 59篇 |
1996年 | 47篇 |
1995年 | 46篇 |
1994年 | 39篇 |
1993年 | 40篇 |
1992年 | 108篇 |
1991年 | 84篇 |
1990年 | 85篇 |
1989年 | 82篇 |
1988年 | 68篇 |
1987年 | 78篇 |
1986年 | 77篇 |
1985年 | 87篇 |
1984年 | 55篇 |
1983年 | 49篇 |
1979年 | 77篇 |
1978年 | 41篇 |
1974年 | 47篇 |
1973年 | 52篇 |
1972年 | 53篇 |
1971年 | 47篇 |
1970年 | 38篇 |
1969年 | 49篇 |
1968年 | 40篇 |
排序方式: 共有7494条查询结果,搜索用时 15 毫秒
1.
Anuj Shrestha Zeeshan Jawa Kathryn L. Koch Amy B. Rankin Qun Xiang Anand Padmanabhan Matthew S. Karafin Joshua J. Field 《Journal of clinical apheresis》2015,30(6):353-358
Red cell exchange (RCE) is a common procedure in adults with sickle cell disease (SCD). Implantable dual lumen Vortex (DLV) ports can be used for RCE in patients with poor peripheral venous access. We performed a retrospective cohort study of RCE procedures performed in adults with SCD. The main objective of the study was to compare the inlet speed, duration of procedures and rate of complications performed through DLV ports to those performed through temporary central venous and peripheral catheters. Twenty‐nine adults with SCD underwent a total of 318 RCE procedures. Twenty adults had DLV ports placed and 218 procedures were performed using DLV ports. Mean length of follow‐up after DLV port placement was 397 ± 263 days. Six DLV ports were removed due to infection and 1 for malfunction after a mean of 171 ± 120 days. Compared to temporary central venous and peripheral catheters, DLV port procedures had a greater rate of procedural complications, a longer duration, and a lower inlet speed (all P < 0.01). When accounting for the maximum allowable inlet speed to avoid citrate toxicity, 40% of DLV port procedures were greater than 10% below maximum speed, compared to 7 and 14% of procedures performed through temporary central venous and peripheral catheters (P < 0.0001). In conclusion, DLV ports can be used for RCE in adults with SCD, albeit with more procedural complications and longer duration. The smaller internal diameter and longer catheter of DLV ports compared to temporary central venous catheters likely accounts for the differences noted. J. Clin. Apheresis 30:353–358, 2015. © 2015 Wiley Periodicals, Inc. 相似文献
2.
3.
4.
5.
6.
7.
Incidence of BK with Tacrolimus Versus Cyclosporine and Impact of Preemptive Immunosuppression Reduction 总被引:8,自引:0,他引:8
Daniel C. Brennan Irfan Agha Daniel L. Bohl Mark A. Schnitzler Karen L. Hardinger Mark Lockwood Stephanie Torrence Rebecca Schuessler Tiffany Roby Monique Gaudreault-Keener Gregory A. Storch 《American journal of transplantation》2005,5(3):582-594
Our purposes were to determine the incidence of BK viruria, viremia or nephropathy with tacrolimus (FK506) versus cyclosporine (CyA) and whether intensive monitoring and discontinuation of mycophenolate (MMF) or azathioprine (AZA), upon detection of BK viremia, could prevent BK nephropathy. We randomized 200 adult renal transplant recipients to FK506 (n = 134) or CyA (n = 66). Urine and blood were collected weekly for 16 weeks and at months 5, 6, 9 and 12 and analyzed for BK by polymerase chain reaction (PCR). By 1 year, 70 patients (35%) developed viruria and 23 (11.5%) viremia; neither were affected independently by FK506, CyA, MMF or AZA. Viruria was highest with FK506-MMF (46%) and lowest with CyA-MMF (13%), p = 0.005. Viruria >/= 9.5 log(10) copies/mL was associated with a 3-fold increased risk of viremia and a 13-fold increased risk of sustained viremia. After reduction of immunosuppression, viremia resolved in 95%, without increased acute rejection, allograft dysfunction or graft loss. No BK nephropathy was observed. Choice of calcineurin inhibitor or adjuvant immunosuppression, independently, did not affect BK viruria or viremia. Viruria was highest with FK506-MMF and lowest with CyA-MMF. Monitoring and preemptive withdrawal of immunosuppression were associated with resolution of viremia and absence of BK nephropathy without acute rejection or graft loss. 相似文献
8.
9.
10.