全文获取类型
收费全文 | 66篇 |
免费 | 3篇 |
专业分类
儿科学 | 1篇 |
基础医学 | 16篇 |
口腔科学 | 1篇 |
临床医学 | 5篇 |
内科学 | 15篇 |
皮肤病学 | 5篇 |
神经病学 | 3篇 |
外科学 | 7篇 |
综合类 | 1篇 |
预防医学 | 7篇 |
眼科学 | 2篇 |
药学 | 3篇 |
肿瘤学 | 3篇 |
出版年
2022年 | 1篇 |
2021年 | 1篇 |
2018年 | 1篇 |
2017年 | 3篇 |
2016年 | 3篇 |
2015年 | 3篇 |
2014年 | 6篇 |
2013年 | 3篇 |
2012年 | 2篇 |
2011年 | 5篇 |
2010年 | 2篇 |
2009年 | 6篇 |
2008年 | 5篇 |
2007年 | 2篇 |
2006年 | 2篇 |
2005年 | 1篇 |
2002年 | 2篇 |
2001年 | 1篇 |
1999年 | 2篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1992年 | 1篇 |
1989年 | 2篇 |
1987年 | 3篇 |
1986年 | 2篇 |
1984年 | 1篇 |
1978年 | 1篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1968年 | 1篇 |
1967年 | 2篇 |
1966年 | 1篇 |
排序方式: 共有69条查询结果,搜索用时 15 毫秒
1.
To study the effect of sorbinil on the alteration of the blood-retinal barrier, 32 adult-onset, non-insulin-dependent diabetic patients with minimal or no retinopathy were randomly assigned to receive either oral sorbinil (250 mg once a day) or a placebo for 6 mo. All patients underwent fundus photography, fluorescein angiography, and vitreous fluorophotometry before treatment and at 3 and 6 mo after treatment. Vitreous fluorophotometry data showed that the alteration of the blood-retinal barrier increased significantly less in the sorbinil-treated group compared with the placebo group during the 6-mo study period. Side effects were limited to hypersensitivity reactions, with skin rash and fever, in only 2 of the 16 patients who received the drug. These hypersensitivity reactions disappeared with discontinuation of the medication. Aldose-reductase inhibition may play an important role in stabilization of the blood-retinal barrier in early diabetic retinopathy. 相似文献
2.
Diogo Franco Nivaldo Alonso Renata Ruas Renato da Silva Freitas Talita Franco 《Child's nervous system》2009,25(11):1455-1458
Purpose
The aim of this study was to highlight the challenges for early diagnosis and the difficulties observed in surgical treatment of patients with transsphenoidal meningoencephalocele associated with cleft lip and/or palate.Method
We evaluated six male patients treated over the course of 4 years. Five patients presented encephalic herniation with nonfunctional brain tissue; one of these presented herniation of the pituitary gland and cerebral ventricles.Results
All the patients received surgical treatment for the cleft lip and/or palate. Only one patient underwent repair of the meningoencephalocele, via nasal endoscopy. There were no postprocedural clinical or surgical complications.Conclusion
The tendency is to avoid neurosurgery, opting for periodic follow-up with magnetic resonance imaging. In the presence of cleft palate, palatoplasty is essential to protect the meningoencephalocele.3.
Eduardo Augusto Ruas André Ricardo Oliveira Conson Bruno Fernandes Costa Juliana Oliveira Damasceno Luana Alves Rodrigues Maikel Reck Ana Odete Santos Vieira Paulo Maurício Ruas Claudete de Fátima Ruas 《Conservation Genetics Resources》2009,1(1):245-248
We isolated and characterized ten microsatellite loci for Luehea divaricata, a South American outcrossing pioneer tree species that is frequently used in reforestation programs of tropical riparian forests in Brazil. A total of 45 alleles were detected across a sample of 42 individuals, with an average number of 4.5 alleles per locus. The average polymorphic information content (PIC) was 0.546 and the observed (H O) and expected (H E) heterozygosity values varied from 0 to 0.929 and 0.194 to 0.821, respectively. Four loci exhibited significant deviation from Hardy-Weinberg equilibrium (P ≤ 0.001) and 24 pair combinations of the ten loci showed significant linkage disequilibrium (P ≤ 0.01). The primers were tested for cross amplification in nine species of the Malvaceae family. These preliminary results demonstrate the usefulness of these microsatellite loci for assessing the genetic structure of L. divaricata and related genera. 相似文献
4.
Leticia Fiss Maria de Lourdes Adrien Clairton Marcolongo-Pereira Nathalia D. Assis-Brasil Eliza S. V. Sallis Franklin Riet-Correa Jerônimo L. Ruas Ana Lucia Schild 《Parasitology research》2013,112(2):883-887
Eight outbreaks of acute and subacute fasciolosis are reported in sheep in the municipality of Santa Vitória do Palmar, southern Brazil, in areas used for irrigated rice cultivation, which are subject to frequent flooding. Two outbreaks occurred mid-winter during July and August, and six occurred during spring and early summer. Morbidity ranged from 3 to 66.7 %, and mortality ranged from 3 to 50 %. Clinical signs included weight loss, mucosal pallor, apathy, depression, muscle tremors, and drooling; these were followed by death within approximately 24 h. Some sheep were found dead. Gross lesions were characterized by an irregular liver capsule with fibrin deposition and hemorrhages. The liver parenchyma contained hemorrhagic tracts or irregular clear areas alternated with dark hemorrhagic areas. Histologically, hemorrhagic dark red tracts of necrotic liver parenchyma and an inflammatory infiltrate were noted; these lesions coincided with the presence of immature flukes. Langhans-type giant cells, fibrous tissue, and bile duct cell proliferation were observed in subacute cases. Chronic fasciolosis is a well-known disease to farmers in southern Brazil; nevertheless, acute and subacute fasciolosis, which are more difficult to diagnose and treat, may cause important economic losses. Efficient control of fasciolosis requires integration of measures to treat infections in the definitive host, to reduce the population of snails of the genus Lymnaea, and to avoid contact between the parasite and host by appropriate pasture management. 相似文献
5.
Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways 总被引:1,自引:0,他引:1
6.
7.
A model of vascular trauma and subsequent reanastomosis with poor postoperative likelihood of patency was developed in the rat femoral artery. Patency rates were significantly improved with intravenous heparin, intragastric aspirin, and both agents together. Heparin yielded higher patency than aspirin. Intimal surfaces of the vessels at various postoperative intervals were observed with the scanning electron microscope. More fibrin accumulation was seen in the aspirin-treated animals, while more platelet aggregation was found in the heparin-treated group. Both platelet aggregation and fibrin strand development appeared retarded with both agents administered. All groups demonstrated good healing of the ruptured intimal surfaces, beginning at 2 days postoperatively. It is concluded that fibrin strand development is a more significant factor in microvascular occlusion than platelet aggregation. 相似文献
8.
9.
10.