Effect of injection ofCryptococcus heteropolysaccharide injection into bone marrow donors and recipients on structure of a heterotopic focus of hematopoiesis

Academician I. P. Pavlov First Leningrad Medical Institute. Leningrad Pharmaceutical Chemical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 105, No. 3, pp. 352–353, March, 1988.     

Effect of ionizing radiation on functional activity of macrophagesĭ

It was shown that in vitro irradiation (8 Gy) of murine peritoneal macrophages suppressed their spontaneous cytotoxity and induced growth-stimulating activity. Exposure to 4 Gy induced mRNA proximal factors--TGF-beta and TNF-alpha and boosted growth-stimulating activity. These effects should be considered when evaluating efficacy of radiotherapy for tumors.     

Use of a plasma clot to assess fibroblast precursors in human bone marrow

Immunology Group, Central Research Laboratory, No. 1 Department of Internal Medicine, I. P. Pavlov First Leningrad Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR N. P. Bekhterev.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 110, No. 7, pp. 70–72, July, 1990.     

Monocytes with Oncogenic Mutation JAK2 V617F as a Tool for Studies of the Pathogenic Mechanisms of Myelofibrosis

Bulletin of Experimental Biology and Medicine - We analyzed previously generated stable monocyte-derived cell line carrying mutation JAK2 V617F. Evaluation of the expression of pro- and...