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排序方式: 共有56条查询结果,搜索用时 31 毫秒
1.
Mejri Nesrine Rym Sellami Raoudha Doghri Hela Rifi Henda Raies Amel Mezlini 《中国肿瘤临床(英文版)》2012,(4):274-276
This paper reports a case of testicular synovial sarcoma with molecular genetic analysis.A 24-year-old male presented with painless scrotal mass.Ultrasonography showed a heterogeneous mass of 66 mm×34 mm in size involving the inguinal region.Histological examination of a surgical biopsy showed a gradeⅢmonophasic growth pattern of spindle cell proliferation.Immunohistochemical analyses indicated positive staining for pancytokeratine and epithelial membrane antigen.Cytogenetic analysis showed the presence of CYT-SSX1 mutation,and CT scan showed non-specific pleural micro-nodules with a size of 7.5 mm.The patient had an extended left orchidectomy but was lost to follow-up for 1 year.A local recurrent scrotal mass of 32 mm×25 mm,multiple inguinal lymph nodes,and increased pleural nodules,which were confirmed by histological examination,were treated with three cycles of adriamycine and ifosfamide chemotherapy,surgical resection,and radiotherapy with complete response.After 3 months,the patient developed local recurrence and pulmonary metastases that did not respond to second-line chemotherapy based on gemcitabine and paclitaxel.The patient had dyspnea at the time of this writing and chest pain,and is under third-line chemotherapy based on Deticene after 30 months of following up.This patient died on November 16,2012 after a resperatory failure and malignant plural effusion. Synovial sarcoma should be considered in the differential diagnosis of soft tissue tumor and it should be aggressively treated to improve prognosis.Although our patient has shown numerous factors of bad prognosis,he has had a relatively long survival time. 相似文献
2.
Ilda Patrícia Ribeiro Francisco Marques Francisco Caramelo José Ferrão Hugo Prazeres Maria José Julião Widad Rifi Suvi Savola Joana Barbosa de Melo Isabel Poiares Baptista Isabel Marques Carreira 《Tumour biology》2014,35(5):4687-4695
Oral tumors are a growing health problem worldwide; thus, it is mandatory to establish genetic markers in order to improve diagnosis and early detection of tumors, control relapses and, ultimately, delineate individualized therapies. This study was the first to evaluate and discuss the clinical applicability of a multiplex ligation-dependent probe amplification (MLPA) probe panel directed to head and neck cancer. Thirty primary oral squamous cell tumors were analyzed using the P428 MLPA probe panel. We detected genetic imbalances in 26 patients and observed a consistent pattern of distribution of genetic alterations in terms of losses and gains for some chromosomes, particularly for chromosomes 3, 8, and 11. Regarding the latter, some specific genes were highlighted due to frequent losses of genetic material—RARB, FHIT, CSMD1, GATA4, and MTUS1—and others due to gains—MCCC1, MYC, WISP1, PTK2, CCND1, FGF4, FADD, and CTTN. We also verified that the gains of MYC and WISP1 genes seem to suggest higher propensity of tumors localized in the floor of the mouth. This study proved the value of this MLPA probe panel for a first-tier analysis of oral tumors. The probemix was developed to include target regions that have been already shown to be of diagnostic/prognostic relevance for oral tumors. Furthermore, this study emphasized several of those specific genetic targets, suggesting its importance to oral tumor development, to predict patients’ outcomes, and also to guide the development of novel molecular therapies. 相似文献
3.
Siham Nasri Imane Guerrouj Widad Abbou Narjiss Aichouni Imane Kamaoui Imane Skiker 《Radiology Case Reports》2022,17(3):572
Many complications are known to occur in association with a diaphragmatic hernia. Acute pancreatitis occurring in this situation is very rare. In this paper, we report a case and describe the radiographic features of this complication. We report an unusual case of acute pancreatitis complicating a neglected post-traumatic diaphragmatic hernia in a 30-year-old male. This patient had a history of an abdominal trauma 5 years ago, and arrived at the emergency room with epigastria and left chest pain and vomiting. Serum lipase was elevated. Acute pancreatitis could be considered as an exceptional complication of diaphragmatic hernia. It is a serious diagnostic and therapeutic challenge. The fundamental roles of CT are to determine the diaphragmatic defect, the abdominal content involving, the Balthazar scoring of pancreatitis, and the presence of local complications. Even if a conservative approach is preferred when facing a diagnosis of pancreatitis, timing of surgery should be carefully considered. 相似文献
4.
Ihssane Afilal Siham Nasri Mustapha Bendaoud Hajar Mahjouba Imane Guerrouj Fathia Aidid Widad Abbou Narjisse Aichouni Imane Kamaoui Imane Skiker 《Radiology Case Reports》2022,17(6):2215
Posterior reversible encephalopathy syndrome is a rare underestimated condition, that generally complicates a rise in blood pressure in an acute setting. This entity has been increasingly identified in patients with systemic lupus erythematosus disease. PRES is challenging to diagnose seeing as it presents with nonspecific neurological symptoms, such as head-aches, confusion, seizures, visual changes or a coma, and can mimic neuropsychiatric lupus. Imaging plays a necessary role in confirming this diagnosis, as it is characterized by vasogenic edema of the posterior white matter, in which the distribution is bilateral and symmetrical. Although this syndrome is rare, early diagnosis allows a prompt treatment and therefore a favorable outcome. We present a case report of PRES in a 14-year-old female previously diagnosed with lupus nephropathy, who presented to the emergency department with seizures and uncontrolled hypertension, that was unfortunately not reversible is this patient. 相似文献
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Dhonneur G Abdi W Ndoko SK Amathieu R Risk N El Housseini L Polliand C Champault G Combes X Tual L 《Obesity surgery》2009,19(8):1096-1101
Background We compared tracheal intubation characteristics and arterial oxygenation quality during airway management of morbidly obese
patients whose trachea was intubated under video assistance with the LMA CTrach™ (SEBAC, Pantin, France) or the Airtraq™ laryngoscope
(VYGON, écouen, France) with that of the conventional Macintosh laryngoscope.
Methods After standardized induction of anesthesia, 318 morbidly obese patients scheduled for elective morbid obesity surgery received
tracheal intubation with the LMA CTrach™, the Airtraq™ laryngoscope, or the conventional Macintosh laryngoscope. Duration
of apnea, time to tracheal intubation, and oxygenation quality during airway management were compared between the LMA CTrach™
and the laryngoscope groups.
Results Patients’ characteristics were similar in the three groups. The success rate for tracheal intubation was 100% with the LMA
CTrach™ and the Airtraq™ laryngoscope. One patient of the Macintosh laryngoscope group received LMA CTrach™ intubation because
of early arterial oxygen desaturation associated with unstable facemask ventilation. The duration of apnea was shorter with
the LMA CTrach™ than that of the Airtraq™ laryngoscope and the Macintosh laryngoscope. The duration tracheal intubation was
shorter with the Airtraq™ laryngoscope than with the Macintosh laryngoscopes and the LMA CTrach™. During airway management,
arterial oxygenation was of better quality with the LMA CTrach™ and the Airtraq™ laryngoscope than that of the Macintosh laryngoscope.
Conclusion Because LMA CTrach™ promoted short apnea time and the Airtraq™ laryngoscope allowed early definitive airway, both video-assisted
tracheal intubation devices prevented most serious arterial oxygenation desaturation evidenced during tracheal intubation
of morbidly obese patients with the conventional Macintosh laryngoscope.
Support was provided solely from department sources. LMA and PRODOL Companies promoted material support for the airways. 相似文献
7.
Adenovirus types associated with severe respiratory diseases: A retrospective 4‐year study in Kuwait
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Wassim Chehadeh Anfal Al‐Adwani Sonia Elezebeth John Shaikhah Al‐Dhufairi Hessa Al‐Dousari Maha Alkhaledi Widad Al‐Nakib 《Journal of medical virology》2018,90(6):1033-1039
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Amathieu R Combes X Abdi W Housseini LE Rezzoug A Dinca A Slavov V Bloc S Dhonneur G 《Anesthesiology》2011,114(1):25-33