全文获取类型
收费全文 | 10852篇 |
免费 | 345篇 |
国内免费 | 132篇 |
专业分类
耳鼻咽喉 | 147篇 |
儿科学 | 184篇 |
妇产科学 | 283篇 |
基础医学 | 2113篇 |
口腔科学 | 233篇 |
临床医学 | 619篇 |
内科学 | 1051篇 |
皮肤病学 | 403篇 |
神经病学 | 830篇 |
特种医学 | 1608篇 |
外科学 | 1438篇 |
综合类 | 78篇 |
预防医学 | 746篇 |
眼科学 | 86篇 |
药学 | 1105篇 |
中国医学 | 91篇 |
肿瘤学 | 314篇 |
出版年
2023年 | 35篇 |
2022年 | 20篇 |
2021年 | 48篇 |
2020年 | 43篇 |
2019年 | 61篇 |
2018年 | 191篇 |
2017年 | 131篇 |
2016年 | 179篇 |
2015年 | 122篇 |
2014年 | 213篇 |
2013年 | 371篇 |
2012年 | 685篇 |
2011年 | 1036篇 |
2010年 | 469篇 |
2009年 | 166篇 |
2008年 | 751篇 |
2007年 | 970篇 |
2006年 | 897篇 |
2005年 | 735篇 |
2004年 | 648篇 |
2003年 | 650篇 |
2002年 | 564篇 |
2001年 | 371篇 |
2000年 | 488篇 |
1999年 | 267篇 |
1998年 | 119篇 |
1997年 | 82篇 |
1996年 | 71篇 |
1995年 | 60篇 |
1994年 | 45篇 |
1993年 | 32篇 |
1992年 | 29篇 |
1991年 | 25篇 |
1990年 | 39篇 |
1989年 | 33篇 |
1988年 | 38篇 |
1987年 | 27篇 |
1986年 | 29篇 |
1985年 | 35篇 |
1984年 | 23篇 |
1983年 | 22篇 |
1982年 | 32篇 |
1981年 | 33篇 |
1980年 | 32篇 |
1979年 | 28篇 |
1978年 | 29篇 |
1976年 | 25篇 |
1975年 | 29篇 |
1974年 | 19篇 |
1963年 | 19篇 |
排序方式: 共有10000条查询结果,搜索用时 9 毫秒
1.
CM Reid M. Nelson P. Beckinsale P. Ryan LMH Wing LJ Beilin MA Brown GLR Jennings CI Johnston J. Marley JJ McNeil TO Morgan J. Shaw ID Steven MJ West 《Clinical and experimental pharmacology & physiology》1997,24(5):370-373
1. The present study aimed to determine the feasibility of conducting a 5 year cardiovascular outcome trial of the treatment of 6000 elderly hypertensive patients in Australian general practices. 2. General practitioners (GPs) were invited to participate by mail and personal follow-up. Patient records were reviewed to identify subjects for a blood pressure (BP) screening programme. Blood pressure was measured on three occasions and eligible subjects were included if the average BP was 160 mmHg systolic or 90 mmHg diastolic if systolic BP was 140 mmHg. 3. Seven hundred and forty-one GPs were approached and 89 were enrolled in the study (12% of mail invites and 75% of those receiving a personal contact). In 16 practices where screening was completed, 82 000 records were reviewed to identify 4% patients eligible for screening. Twenty-two per cent of eligible subjects attended screening. Of 1938 subjects screened, 180 (9%) had BP 5=160/90 mmHg. Forty-seven percent of subjects (n = 916) were receiving antihypertensive therapy and 184 (20%) were withdrawn from therapy. One hundred and sixteen (63%) of these subjects had BP return to study entry levels within 6 weeks. Fifty-seven newly diagnosed and 81 previously treated subjects were randomized (7% of the screened population). 4. Based on the high participation rate of GPs, the response rate of patients to attend a BP screening programme and the 7% randomization to screening ratio for entry into the study, the ANBP2 pilot study has demonstrated that it is feasible to recruit subjects from Australian general practices to a cardiovascular outcome trial. 相似文献
2.
3.
4.
Bošnjaković Petar Ivković Tomislav Ilić Miodrag Aracki Snežana 《Cardiovascular and interventional radiology》1992,15(4):217-220
Flexible tantalum stents (Strecker) were used as an adjunct to percutaneous transluminal angioplasty (PTA) in the treatment
of stenotic arterial or venous limbs of Brescia-Cimino hemodialysis fistulas. The diagnostic procedure was performed using
retrograde fistulography. After PTA with unsatisfactory results, stents were placed in 5 patients with significant residual
stenoses and poor fistula function. Within the mean follow-up period of 6.4 months (range 3–10 months) all fistulas were functioning.
We conclude that Strecker stent is useful in the treatment of stenotic hemodialysis arteriovenous fistulas as an adjunct to
PTA. 相似文献
5.
6.
溴莫尼定对视网膜缺血性损伤神经保护作用的实验研究 总被引:1,自引:1,他引:0
目的:探讨溴莫尼定(brimonidine)对视网膜缺血性损伤神经的保护作用。方法:新西兰大耳白兔32只,随机分为正常对照组、生理盐水治疗组、噻吗心安(timolol)治疗组、brimonidine治疗组,每组8只。后3组为损伤治疗组,通过生理盐水前房高压灌注的方法,制成视网膜缺血动物模型,在视网膜缺血前lh其结膜囊内分剐给予生理盐水、0.5%timolol眼液或0.2%brimonidine眼液局部治疗。在灌注后7d,观察图形视网膜电图(P-ERG)b波振幅变化,并进行组织形态学观察和视网膜神经节细胞(RGC)计数分析。结果:灌注后7d,3个损伤治疗组相对b波振幅恢复率为:7%、11%和64%,RGC标准丢失率为:43%、38%和12%,brimori-die治疗组视网膜组织形态结构接近正常对照组,而生理盐水治疗组和timolol治疗组视网膜内层组织结构损伤明显。结论:Brimonidine局部治疗对缺血诱导的视网膜结构和功能的损害有明显的神经保护作用。 相似文献
7.
MY Mancao LJ Sindel PH Richardson FM Silver 《Acta paediatrica (Oslo, Norway : 1992)》1996,85(1):118-120
Croup is an acute infectious illness usually occurring in children; it is characterized by brassy cough and stridor. The main pathogens include mainly parainfluenza and influenza viruses. Recently there have been reports of prolonged croup caused by the herpes simplex viruses. We report two cases of prolonged croup due to herpes simplex types 1 and 2. We also review and summarize the reported pediatric cases of herpetic croup. 相似文献
8.
Summary The great number of knee-replacement systems makes a comparative study difficult. Even more confusing are the different criteria used for the evaluation of the results. After a critical review of what can be taken as proven facts, our own experience with the semiconstrained GSB-III knee prosthesis is critically analyzed. The survivorship method is used, presenting the cumulative success rate and analyzing the reasons for the failure rates. We feel that all authors presenting results of knee arthroplasty should adopt this method, using the same or at least comparable evaluation sheets (for instance, that of ERASS). Moreover, more attention should be given to bone dynamics in a prospective study using modern technology (CT densitometry). This will help to detect possible factors responsible for the failure of knee arthroplasty and possibly to prevent failure with medication.
Zusammenfassung Die große Zahl verschiedener Kniegelenks-Systeme im prothetischen Ersatz erschwert vergleichendes Studium. Zusätzliche Schwierigkeiten erwachsen aus der Verwendung verschiedener Kriterien bei der Auswertung der Ergebnisse. Wir selbst haben zur Erfahrung mit der GSB-III Knie-Endoprothese kritisch analysiert, nachdem wir versucht haben nur eindeutige Fakten miteinzubeziehen. Wir verwendeten die sogenannte survivorship Methode (Überlebenskurven) und untersuchten die cumulative Erfolgsrate und die Gründe für die Fehlschläge. Wir vertreten die Auffassung, daß alle Autoren, die Ergebnisse über Knie-Arthroplastiken vorstellen, diese Methode verwenden sollten, wenn immer möglich unter Gebrauch desselben oder mindestens vergleichbarer Erhebungsbogen (z. B.相似文献
9.
Baldwin RT Radovancević B Duncan JM Wampler RK Frazier OH 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》1992,19(2):81-86
The Hemopump Cardiac Assist System is a relatively new intraarterial, axial-flow circulatory assist device that offers temporary left ventricular support to patients in refractory cardiogenic shock, without requiring major surgery for insertion. Use of the Hemopump is associated with a low complication rate. Device-related morbidity is extremely rare. Because the Hemopump is safe for use in community hospitals, the number of patients supported by this device is expected to increase. In this report, we present general guidelines for the care of patients supported by the Hemopump. We describe techniques for the management of afterload reduction, supravalvular dislodgement, device malfunction, ventricular ectopy, intracardiac shunting, and inflow cannula obstruction. 相似文献
10.
Ljiljana Ševaljević Sanja Marinković Desanka Bogojević Svetlana Matić Bogdan Bošković 《Archives of toxicology》1989,63(5):406-411
We have studied the effect of soman intoxication on serum acute phase reactants (APR) levels, and the relationship of the APR and corticosterone concentrations and the immunosuppressive activity of the serum. One day after the injection of 1.8 LD50 soman the concentrations of 2-macroglobulin (2-MG) and 1-acid glycoprotein (AGP) in the serum of antidote protected rats increased 4- and 7-fold, respectively, whereas those of hemopexin (Hx), haptoglobin (Hp) and cysteine protease inhibitor (CPI) were two to three times higher than in the controls. A similar magnitude of increase of serum acute phase reactants levels was observed when 0.3 LD50 soman was administered at 24-h intervals over the 5-day period. The relationship of changes in the APR concentration, corticosterone level and immunosuppressive activity of the serum was also comparable to that observed in the acute phase response to tissue injury. 相似文献