全文获取类型
收费全文 | 370篇 |
免费 | 20篇 |
专业分类
儿科学 | 27篇 |
妇产科学 | 15篇 |
基础医学 | 44篇 |
口腔科学 | 7篇 |
临床医学 | 16篇 |
内科学 | 79篇 |
皮肤病学 | 11篇 |
神经病学 | 8篇 |
特种医学 | 44篇 |
外科学 | 48篇 |
综合类 | 5篇 |
预防医学 | 25篇 |
眼科学 | 3篇 |
药学 | 17篇 |
中国医学 | 1篇 |
肿瘤学 | 40篇 |
出版年
2023年 | 2篇 |
2022年 | 4篇 |
2021年 | 9篇 |
2020年 | 2篇 |
2019年 | 3篇 |
2018年 | 4篇 |
2017年 | 6篇 |
2016年 | 4篇 |
2015年 | 9篇 |
2014年 | 4篇 |
2013年 | 10篇 |
2012年 | 15篇 |
2011年 | 14篇 |
2010年 | 14篇 |
2009年 | 15篇 |
2008年 | 13篇 |
2007年 | 15篇 |
2006年 | 12篇 |
2005年 | 9篇 |
2004年 | 9篇 |
2003年 | 11篇 |
2002年 | 11篇 |
2001年 | 2篇 |
2000年 | 12篇 |
1999年 | 7篇 |
1998年 | 14篇 |
1997年 | 8篇 |
1996年 | 15篇 |
1995年 | 7篇 |
1994年 | 14篇 |
1993年 | 14篇 |
1992年 | 9篇 |
1991年 | 10篇 |
1990年 | 15篇 |
1989年 | 8篇 |
1988年 | 7篇 |
1987年 | 3篇 |
1986年 | 3篇 |
1985年 | 4篇 |
1983年 | 8篇 |
1982年 | 4篇 |
1981年 | 2篇 |
1977年 | 2篇 |
1976年 | 4篇 |
1975年 | 2篇 |
1974年 | 2篇 |
1971年 | 4篇 |
1969年 | 2篇 |
1967年 | 2篇 |
1966年 | 2篇 |
排序方式: 共有390条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
LEE JS IM HH JUNG Y JUNG IS JANG JY CHUN YK CHO YD KIM JO CHO JY KIM YS SHIM CS & KIM BS 《Neurogastroenterology and motility》2006,18(6):493-494
Background: Recent development of extracorporeal magnetic stimulation (ECMS) which uses current‐changing magnetic fields allows the induction of electrical stimulation in the desired deep tissue. Recent study showed the sacral nerve stimulation reduces corticoanal excitability that may play a functional role in anal continence mechanisms. Preliminary study shows that ECMS of sacral nerve can modify pelvic floor function and expel rectal balloon in patients with pelvic floor dyssynergia (PFD). Aims: To evaluate the effect of ECMS compared with biofeedback therapy (BF) in patients with PFD. Methods and Materials: Thirty‐eight patients who fulfilled Rome II criteria for PFD by colon transit time and anorectal function tests, were randomly treated with 8 sessions of ECMS (2/weeks; n = 19) at prone position or BF (2/weeks; n = 19) at sitting position. Stimulation parameters were set at 50–80% of maximum intensity, 10 and 50 Hz frequency, 3 s burst length with 3 and 6 s off using arm‐typed stimulator (BioCom‐1000, Mcube Co., Korea). Symptom scores for constipation with/without anorectal function test were repeatedly measured after each treatment. Response was defined as 50% or more decreased symptom score after treatment (partial response: 30–50%, poor: <30%). Results: Fifteen patients (age 49.1 ± 13.4 years, mean ± SD; 4 men) completed 8 session of BF and 14 patients (54.5 ± 17.6 years, 3 men) completed 8 session of ECMS. Four patients of BF group discontinued treatment due to unsatisfactory therapeutic effect (n = 1) and withdrew consent (n = 3) and 5 patients of ECMS group discontinued treatment because of same reasons (n = 1, 4). Total symptom scores were significantly decreased after treatment of 8 session in both treatment groups (13.4 ± 6.6 vs. 4.3 ± 4.0 for BF, p = 0.009; 14.9 ± 5.6 vs. 3.4 ± 4.0 for ECMS, p < 0.001). Bowel movements per week were also significantly increased after treatment in both groups (median 2 vs. 7 for BF, p = 0.035; median 2 vs. 7 for ECMS, p = 0.008). Thirteen out of 15 patients showed response in BF group and 12 out of 14 showed good response in ECMS group. No adverse effects in both groups. Conclusions: ECMS is as effective as BF for the treatment of PFD. Long‐term effect of ECMS for the patients with pelvic floor dyssynergia need to be evaluated in the near future. 相似文献
5.
6.
IM Hann 《Journal of clinical pathology》1989,42(2):221-222
7.
Oocyte morphology predicts outcome of intracytoplasmic sperm injection 总被引:10,自引:14,他引:10
Serhal PF; Ranieri DM; Kinis A; Marchant S; Davies M; Khadum IM 《Human reproduction (Oxford, England)》1997,12(6):1267-1270
To examine the influence of cytoplasmic morphology on the success rate of
intracytoplasmic sperm injection (ICSI), the morphology of 837 metaphase II
oocytes was assessed after cumulus stripping. The main abnormalities
detected were excessive granularity, cytoplasmic inclusions such as
vacuoles, smooth endoplasmic reticulum clustering and refractile bodies.
Microinjection was performed in 538 oocytes with normal cytoplasm, 142 out
of 161 with excessive granularity and 112 out of 138 with cytoplasmic
inclusions. Very poor oocytes were not injected. No difference was found in
fertilization rate. The embryos achieved cleaved normally and a similar
number of good quality embryos among the three groups was noted. The
outcome of transfer of embryos derived solely from normal oocytes (group A:
72 patients, 183 embryos) was compared with those from oocytes with
cytoplasmic abnormalities (group B: 34 patients, 85 embryos). In group A,
17 clinical pregnancies (24% per patient, implantation rate 10%) were
established. In group B, only one clinical pregnancy (3% per patient,
implantation rate 1%) was established, from the transfer of embryos derived
from oocytes with homogeneous granularity of the cytoplasm. No pregnancy
resulted following the transfer of embryos from eggs with cytoplasmic
inclusions. The difference was statistically significant. The outcome of
ICSI is dependent on the quality of the oocytes retrieved. Normal
fertilization and early embryo development were achieved in oocytes with
abnormal cytoplasm morphology, but the resulting embryos failed to
demonstrate the same implantation potential as those derived from oocytes
with normal cytoplasm.
相似文献
8.
The aim of this study was to study pulmonary radiological abnormalities with chest radiography following different radiotherapy
(RT) techniques for breast cancer with respect to regions and density, and their association with pulmonary complications
and reduction in vital capacity (VC). Chest radiographs were performed 5 months following local or loco-regional RT in 167
breast cancer patients. The radiological abnormalities were analysed with a classification system originally proposed by Arriagada
and evaluated according to increasing density (0–3) and affected lung regions (apical–lateral, basal–lateral, central–parahilar).
The highest-density grades in each region were added together to form scores ranging from 0 to 9. The patients were monitored
for RT-induced pulmonary complications. The VC was measured prior to and 5 months following RT. An independent evaluation
of 51 patients was performed by a second radiologist to control the reproducibility of the classification system. Increasing
scores were associated with loco-regional RT and pulmonary complications (P < 0.001). The mean reduction of VC for patients scoring 0–3 (–30 ml) vs 4–9 (–161 ml) was not statistically significant (P = 0.10). Scores of 4–9 were more frequently observed in older patients (P < 0.001). The independent evaluations by two radiologists revealed good agreement (P < 0.001) and no systematic inter-observer variation. Radiological abnormalities on chest radiographs, scored according to
Arriagada, can be used as an objective end point for RT-induced pulmonary side effects in breast cancer.
Received: 4 February 1999; Revision received: 1 April 1999; Accepted: 5 May 1999 相似文献
9.
Nutrient re‐routing and altered gut‐islet cell crosstalk may explain early relief of severe postprandial hypoglycaemia after reversal of Roux‐en‐Y gastric bypass
下载免费PDF全文
![点击此处可从《Diabetic medicine》网站下载免费的PDF全文](/ch/ext_images/free.gif)
10.