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Nair BT Bhat SH Narayan UV Sukumar S Saheed M Kurien G Sudhindran S 《Transplantation proceedings》2007,39(10):3477-3480
A widening gap between supply and demand for transplantable kidneys has led to increasing use of marginal living donors from an elderly population in kidney transplantation programs. Although the graft survivals of these marginal organs are comparable with those of standard donors, the attendant risk of transmission of malignancy from older donors is high, given that aging is a risk factor for malignancy. Herein we have highlighted a case of small cell carcinoma developing in a marginal elderly donor at 10 months after kidney donation. The recipient remains free of malignancy at 36 months after transplantation. The exhaustiveness of tests for screening of elderly living donors for malignancy as well as the surveillance of recipients at high risk of developing donor-derived malignancy remain uncertain. 相似文献
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Nair B Nambiar A Hattangadi SB Sukumar S Saifuddin MS 《Scandinavian journal of urology and nephrology》2007,41(5):442-444
Solitary fibrous tumours, which are commonly described as arising from the pleura, are rarely seen in the lower urinary tract. Although malignant changes have been reported, these tumours are usually benign. This case report discusses the radiological features, management strategy and histopathology of a solitary fibrous tumour arising from the prostate. 相似文献
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Ebola virus disease – gaps in knowledge and practice among healthcare workers in Lagos,August 2014
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Abisola M. Oladimeji Saheed Gidado Patrick Nguku Iruoma Genevieve Nwangwu Nikhil D. Patil Femi Oladosu Alero Ann Roberts Ndadilnasiya E. Waziri Faisal Shuaib Olukayode Oguntimehin Emmanuel Musa Abdulsalami Nasidi Peter Adewuyi Adebola Olayinka Oladoyin Odubanjo N‐FELTP Residents Gabriele Poggensee 《Tropical medicine & international health : TM & IH》2015,20(9):1162-1170
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Frederick K. Korley MD PhD Steven P. Schulman MD Lori J. Sokoll PhD Andrew P. DeFilippis MD MSc Andrew I. Stolbach MD Jamil D. Bayram MD MPH MEd Mustapha O. Saheed MD Rodney Omron MD MPH Christopher Fernandez Albert Lwin Stephen S. Cai Wendy S. Post MD Allan S. Jaffe MD 《Academic emergency medicine》2014,21(7):727-735
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SO Afolabi AJ Akindele O Awodele CC Anunobi OO Adeyemi 《BMC complementary and alternative medicine》2012,12(1):79
ABSTRACT: BACKGROUND: The herbal preparation DAS-77, used for the treatment of various ailments in Nigeria, contains the milled bark of Mangifera indica L. and root of Carica papaya L. Toxicological assessment of the preparation was carried out in this study. METHODS: In the acute toxicity study, DAS-77 was administered to mice p.o.up to 10 g/kg and i.p. at 250-3000 mg/kg. Mortality within 24 h was recorded. In the chronic toxicity study, rats were treated p.o. for 90 days at doses of 80, 400 (therapeutic dose, TD) and 2000 mg/kg. By 90 days, animals were sacrificed and blood samples collected for hematological and biochemical analysis. Organs were harvested for weight determination, antioxidants and histopathological assessments. RESULTS: DAS-77 did not produce any lethality administered p.o. up to 10 g/kg but the i.p. LD50 was 1122.0 mg/kg. At TD, DAS-77 produced significant (p<0.05) reductions in body weight, food intake and K+, and increases in ovary weight, neutrophils and HDL, which were reversible. Histopathological presentations were generally normal. Effects at the other doses were comparable to those at TD except for reversible increases in antioxidants in the liver, kidney and testes, and sperm abnormality, and reductions in liver enzymes, sperm motility and count. CONCLUSIONS: Findings in this study revealed that DAS-77 is relatively safe with the potential for enhancing in vivo antioxidant activity. However, possibly reversible side-effects include electrolyte imbalance and sterility in males. 相似文献
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Adedeji Isaac Akinkunmi Lawal Saheed Akinmayowa Aluko-Arowolo Sola 《Cancer causes & control : CCC》2021,32(8):895-901
Cancer Causes & Control - In Nigeria, knowledge about prostate cancer (PCa) is poor, so are the availability, accessibility, and utilization of PCa screening services. Poor knowledge increases... 相似文献
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2010年世界胃肠病学组织关于炎症性肠病诊断和治疗的实践指南 总被引:2,自引:0,他引:2
Michael Fried J.H.Krabshuis Henry Cohen R.Eliakim Suleiman Fedail Richard Gearry K.L.Goh Saheed Hamid A.W.LeMair Malfertheiner Qin Ouyang J.F.Rey Ajit Sood Ole O.Thomsen Alan Thomson 杨钊斌 《胃肠病学》2010,15(9):548-558
炎症性肠病(IBD)是一组特发性、慢性、炎症性肠道疾病状态,包括两种主要类型:克罗恩病(CD)和溃疡性结肠炎(UC),两者的临床和病理特征既有重叠又有区别。IBD过去常见于发达国家,近几十年,发展中国家的患病率逐步上升。本指南就IBD诊断和治疗方面提出的独特议题在当前的文献和指南中几乎从未被提及。由于各地区的IBD临床特点差异较大,因此根据患者的主诉诊断IBD或评估疾病活动度需随地区的变化而变化。同样,治疗亦应根据疾病的分类和当地医疗资源进行调整。世界胃肠病学组织根据世界各国医疗资源的差异,采用级联方法制订了IBD的诊疗指南。 相似文献