全文获取类型
收费全文 | 15210篇 |
免费 | 785篇 |
国内免费 | 77篇 |
专业分类
耳鼻咽喉 | 192篇 |
儿科学 | 232篇 |
妇产科学 | 205篇 |
基础医学 | 2118篇 |
口腔科学 | 348篇 |
临床医学 | 1440篇 |
内科学 | 3145篇 |
皮肤病学 | 493篇 |
神经病学 | 1444篇 |
特种医学 | 974篇 |
外科学 | 2218篇 |
综合类 | 72篇 |
一般理论 | 1篇 |
预防医学 | 603篇 |
眼科学 | 361篇 |
药学 | 992篇 |
中国医学 | 49篇 |
肿瘤学 | 1185篇 |
出版年
2023年 | 58篇 |
2022年 | 101篇 |
2021年 | 236篇 |
2020年 | 185篇 |
2019年 | 221篇 |
2018年 | 266篇 |
2017年 | 272篇 |
2016年 | 287篇 |
2015年 | 362篇 |
2014年 | 397篇 |
2013年 | 582篇 |
2012年 | 931篇 |
2011年 | 1010篇 |
2010年 | 619篇 |
2009年 | 658篇 |
2008年 | 1025篇 |
2007年 | 1075篇 |
2006年 | 1064篇 |
2005年 | 1071篇 |
2004年 | 1023篇 |
2003年 | 1023篇 |
2002年 | 918篇 |
2001年 | 190篇 |
2000年 | 154篇 |
1999年 | 208篇 |
1998年 | 223篇 |
1997年 | 171篇 |
1996年 | 148篇 |
1995年 | 110篇 |
1994年 | 107篇 |
1993年 | 77篇 |
1992年 | 83篇 |
1991年 | 82篇 |
1990年 | 73篇 |
1989年 | 68篇 |
1988年 | 55篇 |
1987年 | 62篇 |
1986年 | 54篇 |
1985年 | 55篇 |
1984年 | 63篇 |
1983年 | 57篇 |
1982年 | 50篇 |
1981年 | 42篇 |
1980年 | 48篇 |
1979年 | 34篇 |
1978年 | 45篇 |
1977年 | 38篇 |
1976年 | 35篇 |
1974年 | 29篇 |
1973年 | 34篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
T. Kapellen A. Galler K. Claus S. Heger D. Härtig Prof. Dr. W. Kiess 《Der Diabetologe》2006,2(2):167-181
Type 1 diabetes is one of the commonest chronic disorders encountered in children and adolescents. When it first becomes apparent in children, approximately 20% of them have clinical and biochemical signs of ketoacidosis (DKA). In the presence of unusual clinical symptoms it is necessary to consider the possibility of associated conditions, such as coeliac disease, immunothyroiditis and Addison’s disease. Children with diabetes must be treated by a multidisciplinary team made up of paediatrician, paediatric diabetes specialist, psychologist, social worker, ophthalmologist, dietitian, nurse and diabetes counsellor, making it essential for them to be treated in regional specialised centres. They are treated in their own psychosocial environment and their families are involved in the therapy. Comprehensive, multidisciplinary treatment strategies have now made it possible for these patients to enjoy normal physical wellbeing and near-normal psychosocial development. Prevention and early treatment of of disturbances associated with diabetes remain an important concern. The fact that type 2 diabetes must now be looked for in overweight children and adolescents is a new aspect of diabetes medicine. 相似文献
4.
Lei Li Jürgen Bruns Reinhard E. Friedrich Rainer Schmelzle 《European journal of plastic surgery》2006,29(2):93-96
Adamantinoma of long bones is one of the rarest of malignant bone tumors; it is commonly located in the middle or lower third of the diaphysis of the tibia. A case with multiple occurrences affecting both the tibia and fibula is presented. En bloc resection with wide operative margins was performed, and a large tibial defect of 23 cm was effectively bridged by a revascularized free fibular flap. At 13 months follow-up, there was no sign of local recurrence or metastasis, and the patient was mobile. 相似文献
5.
The influence of short‐term confinement and moderate exercise on tibia development was investigated in growing pigs (36–41 kg, 10 weeks at the beginning of the study). Animals were kept for 2 weeks either in individual crates of 0.8 m2 (‘confinement’, n = 4) or kept in groups of four animals in large crates of 5.6 m2 without (‘control’) or with additional exercise (30 min walking at 5 days/week; ‘exercise’). Bone density and morphological parameters were evaluated by computer tomography (CT). Periosteal apposition and longitudinal growth were determined after polychrome sequential labelling in weekly intervals. Cortical areas of the cross sections at the mid‐shaft and at 75% of the length of the bone measured distal to the carpus by CT were significantly correlated to each other (r = 0.70) and revealed a significant reduction in confined animals. This difference was explained by lower periosteal apposition rates in these animals compared with exercised and group‐housed pigs. Similarly longitudinal growth and the formation and calcification of spongiosa of the tibiae were inhibited by confinement. Thus, 2 weeks of confinement led to significant differences in bone growth and metabolism in young growing piglets when compared with animals with moderate activity. 相似文献
6.
Jan M?schwitzer Rainer H Müller 《European journal of pharmaceutics and biopharmaceutics》2006,62(3):282-287
High pressure homogenization can be employed to produce drug nanocrystals with a number of advantages, like improved solubility behaviors, better drug targeting or even increased mucoadhesiveness. To obtain a controlled drug delivery system it is necessary to transform the resulting nanosuspension into a solid dosage form. The present study shows the feasibility to use a mucoadhesive nanosuspension of poorly soluble hydrocortisone acetate produced by high pressure homogenization as layering dispersion in a fluidized bed process, followed by the application of an enteric coating to achieve a controlled drug release. To point out the advantages of drug nanocrystals the new fomulation was compared with a formulation containing micronized drug. Both formulations were characterized with regard to their particle size and crystallinity by using laser diffractometry, photon correlation spectroscopy and X-ray diffraction. The pellet morphology was characterized by using the environmental scanning electron microscopy (ESEM). In the in vitro dissolution tests an accelerated dissolution velocity and an increased drug release could be shown for the pellets containing drug nanocrystals. 相似文献
7.
8.
9.
10.