全文获取类型
收费全文 | 1177篇 |
免费 | 56篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 43篇 |
妇产科学 | 23篇 |
基础医学 | 115篇 |
口腔科学 | 23篇 |
临床医学 | 102篇 |
内科学 | 289篇 |
皮肤病学 | 6篇 |
神经病学 | 91篇 |
特种医学 | 323篇 |
外科学 | 53篇 |
综合类 | 15篇 |
预防医学 | 42篇 |
眼科学 | 3篇 |
药学 | 72篇 |
中国医学 | 3篇 |
肿瘤学 | 46篇 |
出版年
2023年 | 6篇 |
2022年 | 5篇 |
2021年 | 15篇 |
2020年 | 4篇 |
2019年 | 10篇 |
2018年 | 20篇 |
2017年 | 12篇 |
2016年 | 15篇 |
2015年 | 25篇 |
2014年 | 14篇 |
2013年 | 26篇 |
2012年 | 32篇 |
2011年 | 30篇 |
2010年 | 24篇 |
2009年 | 28篇 |
2008年 | 32篇 |
2007年 | 40篇 |
2006年 | 39篇 |
2005年 | 31篇 |
2004年 | 22篇 |
2003年 | 17篇 |
2002年 | 22篇 |
2001年 | 23篇 |
2000年 | 19篇 |
1999年 | 25篇 |
1998年 | 54篇 |
1997年 | 48篇 |
1996年 | 61篇 |
1995年 | 43篇 |
1994年 | 37篇 |
1993年 | 42篇 |
1992年 | 18篇 |
1991年 | 14篇 |
1990年 | 14篇 |
1989年 | 35篇 |
1988年 | 41篇 |
1987年 | 35篇 |
1986年 | 32篇 |
1985年 | 47篇 |
1984年 | 23篇 |
1983年 | 23篇 |
1982年 | 26篇 |
1981年 | 24篇 |
1980年 | 13篇 |
1979年 | 7篇 |
1978年 | 9篇 |
1977年 | 26篇 |
1976年 | 18篇 |
1975年 | 15篇 |
1969年 | 3篇 |
排序方式: 共有1255条查询结果,搜索用时 15 毫秒
1.
Trine Juhler N?ttrup Stine Sofia Korreman Anders Navrsted Pedersen Lasse Rye Aarup H?kan Nystr?m Mikael Olsen Lena Specht 《Radiotherapy and oncology》2007,84(1):40-48
BACKGROUND AND PURPOSE: This study aimed at quantifying the breathing variations among lung cancer patients over full courses of fractionated radiotherapy. The intention was to relate these variations to the margins assigned to lung tumours, to account for respiratory motion, in fractionated radiotherapy. MATERIALS AND METHODS: Eleven lung cancer patients were included in the study. The patients' chest wall motions were monitored as a surrogate measure for breathing motion during each fraction of radiotherapy by use of an external optical marker. The exhale level variations were evaluated with respect to exhale points and fraction-baseline, defined for intra- and interfraction variations respectively. The breathing amplitude was evaluated as breathing cycle amplitudes and fraction-max-amplitudes defined for intra- and interfraction breathing, respectively. RESULTS: The breathing variations over a full treatment course, including both intra- and interfraction variations, were 15.2mm (median over the patient population), range 5.5-26.7mm, with the variations in exhale level as the major contributing factor. The median interfraction span in exhale level was 14.8mm, whereas the median fraction-max-amplitude was 6.1mm (median of patient individual SD 1.4). The median intrafraction span in exhale level was 1.6mm, and the median breathing cycle amplitude was 4.0mm (median of patient individual SD 1.4). CONCLUSIONS: The variations in externally measured exhale levels are larger than variations in breathing amplitude. The interfraction variations in exhale level are in general are up to 10 times larger than intrafraction variations. Margins to account for respiratory motion cannot safely be based on one planning session, especially not if relying on measuring external marker motion. Margins for lung tumours should include interfraction variations in breathing. 相似文献
2.
3.
4.
Kallol Ray Chaudhuri Pablo Martinez-Martin Anthony H V Schapira Fabrizio Stocchi Kapil Sethi Per Odin Richard G Brown William Koller Paolo Barone Graeme MacPhee Linda Kelly Martin Rabey Doug MacMahon Sue Thomas William Ondo David Rye Alison Forbes Susanne Tluk Vandana Dhawan Annette Bowron Adrian J Williams Charles W Olanow 《Movement disorders》2006,21(7):916-923
Nonmotor symptoms (NMS) of Parkinson's disease (PD) are not well recognized in clinical practice, either in primary or in secondary care, and are frequently missed during routine consultations. There is no single instrument (questionnaire or scale) that enables a comprehensive assessment of the range of NMS in PD both for the identification of problems and for the measurement of outcome. Against this background, a multidisciplinary group of experts, including patient group representatives, has developed an NMS screening questionnaire comprising 30 items. This instrument does not provide an overall score of disability and is not a graded or rating instrument. Instead, it is a screening tool designed to draw attention to the presence of NMS and initiate further investigation. In this article, we present the results from an international pilot study assessing feasibility, validity, and acceptability of a nonmotor questionnaire (NMSQuest). Data from 123 PD patients and 96 controls were analyzed. NMS were highly significantly more prevalent in PD compared to controls (PD NMS, median = 9.0, mean = 9.5 vs. control NMS, median = 5.5, mean = 4.0; Mann-Whitney, Kruskal-Wallis, and t test, P < 0.0001), with PD patients reporting at least 10 different NMS on average per patient. In PD, NMS were highly significantly more prevalent across all disease stages and the number of symptoms correlated significantly with advancing disease and duration of disease. Furthermore, frequently, problems such as diplopia, dribbling, apathy, blues, taste and smell problems were never previously disclosed to the health professionals. 相似文献
5.
6.
7.
Lynn Marie Trotti David B Rye Donald L Bliwise 《Movement disorders》2007,22(10):1520; author reply 1520-1520; author reply 1521
8.
A randomized controlled trial of electromagnetic therapy in the primary care management of venous leg ulceration 总被引:1,自引:1,他引:0
OBJECTIVE: The aim was to establish the potential efficacy, tolerabilityand side-effect profile of electromagnetic therapy as an adjunctto conventional dressings in the treatment of venous leg ulcers. METHOD: A prospective, randomized, double blind controlled clinicaltrial was carried out in a dedicated leg ulcer clinic basedin one urban general practice. Nineteen patients with leg ulcersof confirmed venous aetiology were assessed. The main outcomemeasures were rate and scale of venous leg ulcer healing, changesin patient-reported pain levels, quality of life, degree ofmobility, side effect profile and acceptability to patientsand staff. RESULTS: Sixty-eight per cent of patients attending this dedicated clinicachieved improvements in the size of their ulcer (4, 21%, healedfully) and in reduced pain levels (P < 0.05) during the trial,despite the chronicity of ulcer histories. Patients treatedwith electromagnetic therapy at 800 Hz were found at day 50to have significantly greater healing (P < 0.05) and paincontrol (P < 0.05) than placebo therapy or treatment with600 Hz. All patients reported improved mobility at the end ofthe study. The electromagnetic therapy was well tolerated bypatients, with no differences between groups in reporting adverseevents, and proved acceptable to staff. CONCLUSION: Despite the small numbers in this pilot study, electromagnetictherapy provided significant gains in the healing of venousleg ulcers and reduction in pain. Keywords. Electromagnetic therapy, RCT, leg ulcers, primary care. 相似文献
9.
10.