全文获取类型
收费全文 | 2886篇 |
免费 | 171篇 |
国内免费 | 171篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 94篇 |
妇产科学 | 22篇 |
基础医学 | 395篇 |
口腔科学 | 57篇 |
临床医学 | 431篇 |
内科学 | 589篇 |
皮肤病学 | 130篇 |
神经病学 | 123篇 |
特种医学 | 376篇 |
外科学 | 278篇 |
综合类 | 32篇 |
预防医学 | 113篇 |
眼科学 | 20篇 |
药学 | 333篇 |
1篇 | |
中国医学 | 35篇 |
肿瘤学 | 183篇 |
出版年
2023年 | 11篇 |
2022年 | 28篇 |
2021年 | 44篇 |
2020年 | 29篇 |
2019年 | 50篇 |
2018年 | 61篇 |
2017年 | 57篇 |
2016年 | 82篇 |
2015年 | 108篇 |
2014年 | 141篇 |
2013年 | 157篇 |
2012年 | 192篇 |
2011年 | 202篇 |
2010年 | 134篇 |
2009年 | 127篇 |
2008年 | 136篇 |
2007年 | 223篇 |
2006年 | 135篇 |
2005年 | 119篇 |
2004年 | 110篇 |
2003年 | 95篇 |
2002年 | 81篇 |
2001年 | 29篇 |
2000年 | 25篇 |
1999年 | 36篇 |
1998年 | 95篇 |
1997年 | 84篇 |
1996年 | 76篇 |
1995年 | 65篇 |
1994年 | 50篇 |
1993年 | 55篇 |
1992年 | 13篇 |
1991年 | 18篇 |
1990年 | 15篇 |
1989年 | 54篇 |
1988年 | 36篇 |
1987年 | 32篇 |
1986年 | 28篇 |
1985年 | 24篇 |
1984年 | 20篇 |
1983年 | 14篇 |
1982年 | 27篇 |
1981年 | 14篇 |
1980年 | 15篇 |
1979年 | 6篇 |
1978年 | 4篇 |
1977年 | 17篇 |
1976年 | 30篇 |
1975年 | 13篇 |
1965年 | 3篇 |
排序方式: 共有3228条查询结果,搜索用时 15 毫秒
1.
Volume control associated with better cardiac function in long-term peritoneal dialysis patients. 总被引:4,自引:0,他引:4
Gulay A?ci Mehmet Ozkahya Soner Duman Huseyin Toz Sinan Erten Ercan Ok 《Peritoneal dialysis international》2006,26(1):85-88
BACKGROUND: This study was undertaken to investigate the effect of long-term blood pressure (BP) reduction, achieved with salt restriction and strict volume control, on frequency and regression of left ventricular hypertrophy (LVH) in long-term peritoneal dialysis (PD) patients. METHODS: 56 patients who had been treated for more than 2 years under our care were enrolled. After echocardiographic (Echo) evaluation, 46 patients were included in the follow-up study. In our unit, we aim to keep patients' BP below 130/85 mmHg and cardiothoracic index below 0.50. To reach these targets, moderate salt restriction is advised, and if necessary, hypertonic PD solutions are used. Echo was performed at the beginning of the study (after a mean period of 36 months on PD) and at the end of the prospective follow-up period (24 months later). RESULTS: At the time of the first Echo, LVH was detected in only 8 (21%) patients. Residual urine volume was significantly decreased compared to data taken when they first started PD (658 +/- 795 vs 236 +/- 307 mL/day). Mean left ventricular mass index (LVMI) was 107 +/- 26.5 g/m2. LVMI was significantly decreased at the end of the follow-up in patients who had LVH at baseline. No LVH developed in patients who had normal LVMI at baseline. CONCLUSION: Our results indicate that control of hypertension is possible when extracellular fluid volume is kept under control using hypertonic PD solutions in case of recruitment in addition to salt restriction in long-term PD patients. Sustained normovolemia is associated with low incidence and regression of LVH. 相似文献
2.
Eun Sang Park Jung Im Na Seon Ok Kim Chang Hun Huh Sang Woong Youn Kyoung Chan Park 《Skin research and technology》2006,12(4):298-302
Background/purpose: Vitiligo and nevus depigmentosus (ND) present similar hypopigmented macules with significantly different prognoses. Although the distinction between the two diseases is important, differential diagnosis relies on medical history and physical examination, which is far from decisive in some cases. The Mexameter® is an objective skin color-measuring device, and has been reported to provide a reproducible and sensitive means of quantifying small skin color differences. In this study, we investigated the usefulness of a Mexameter® for discriminating these diseases.
Methods: A selection of 202 hypopigmented skin lesions (182 from vitiligo and 20 from ND) were the objects of this study. Using a Mexameter, MIs were obtained from lesions and symmetrically located control skin. RMIs, ratios of the MIs of lesional skins to control skins, were calculated.
Results: The mean MIs and RMIs were significantly different for vitiligo and ND. The mean RMI of ND lesions was 74±13, which was significantly higher than that of vitiligo lesions (50±24). No ND lesion had an RMI of <50%.
Conclusion: This study shows that the Mexameter® , an objective pigment-measuring device, can be used to achieve a more accurate diagnosis of hypopigmentary disorders, and that the relative melanin index (RMI), which represents the relative pigment levels, might be a more effective parameter than the melanin index (MI) itself for comparing pigmentation differences. 相似文献
Methods: A selection of 202 hypopigmented skin lesions (182 from vitiligo and 20 from ND) were the objects of this study. Using a Mexameter, MIs were obtained from lesions and symmetrically located control skin. RMIs, ratios of the MIs of lesional skins to control skins, were calculated.
Results: The mean MIs and RMIs were significantly different for vitiligo and ND. The mean RMI of ND lesions was 74±13, which was significantly higher than that of vitiligo lesions (50±24). No ND lesion had an RMI of <50%.
Conclusion: This study shows that the Mexameter
3.
4.
5.
6.
Adverse reaction to intravenous gadoteridol 总被引:1,自引:0,他引:1
7.
8.
9.
Hyun Chul Kim Sang Woo Nam Yong Keun Cho Hey Jin Jeong Se In Kim Seong Hun Kim Chul Min An In Hee Kim Sang Wook Kim Seung Ok Lee Soo Teik Lee 《Taehan Sohwagi Hakhoe chi》2006,47(3):233-237
Although adenocarcinoma is a well known complication of chronic inflammatory bowel disease, primary gastrointestinal lymphoma occurring in Crohn's disease is rare. A 40-year-old man with 10 year-history of Crohn's disease had multiple longitudinal ulcerative lesions on descending colon in follow-up colonoscopic examination. Microscopic examination of proximal descending colon revealed peripheral T cell lymphoma and other site of the descending colon was consistent with Crohn's disease. The patient reached complete remission of malignant lymphoma after three cycles of combined chemotherapy. He has been well for 10 months with sulfasalazine maintenance therapy but was admitted to the hospital due to spontaneous bowel perforation of ascending colon. Right hemicolectomy was done, but the patient died of post-surgical recurrent mesenteric abscess and sepsis. To the best of our knowledge, this is the first case of Non-Hodgkin's lymphoma complicating Crohn's disease in Korea which was confirmed by immunohistochemical studies. 相似文献
10.