全文获取类型
收费全文 | 9692篇 |
免费 | 573篇 |
国内免费 | 70篇 |
专业分类
耳鼻咽喉 | 71篇 |
儿科学 | 247篇 |
妇产科学 | 174篇 |
基础医学 | 1512篇 |
口腔科学 | 224篇 |
临床医学 | 686篇 |
内科学 | 2318篇 |
皮肤病学 | 236篇 |
神经病学 | 772篇 |
特种医学 | 367篇 |
外科学 | 1370篇 |
综合类 | 32篇 |
预防医学 | 381篇 |
眼科学 | 262篇 |
药学 | 722篇 |
中国医学 | 23篇 |
肿瘤学 | 938篇 |
出版年
2023年 | 48篇 |
2022年 | 98篇 |
2021年 | 227篇 |
2020年 | 111篇 |
2019年 | 135篇 |
2018年 | 215篇 |
2017年 | 193篇 |
2016年 | 201篇 |
2015年 | 201篇 |
2014年 | 300篇 |
2013年 | 337篇 |
2012年 | 499篇 |
2011年 | 631篇 |
2010年 | 360篇 |
2009年 | 303篇 |
2008年 | 560篇 |
2007年 | 615篇 |
2006年 | 607篇 |
2005年 | 621篇 |
2004年 | 525篇 |
2003年 | 525篇 |
2002年 | 512篇 |
2001年 | 197篇 |
2000年 | 203篇 |
1999年 | 209篇 |
1998年 | 123篇 |
1997年 | 80篇 |
1996年 | 71篇 |
1995年 | 57篇 |
1994年 | 73篇 |
1993年 | 59篇 |
1992年 | 104篇 |
1991年 | 115篇 |
1990年 | 111篇 |
1989年 | 113篇 |
1988年 | 110篇 |
1987年 | 116篇 |
1986年 | 98篇 |
1985年 | 78篇 |
1984年 | 66篇 |
1983年 | 40篇 |
1982年 | 34篇 |
1980年 | 27篇 |
1979年 | 36篇 |
1978年 | 30篇 |
1977年 | 27篇 |
1975年 | 32篇 |
1974年 | 41篇 |
1970年 | 28篇 |
1967年 | 27篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Chie Teramoto PHN RN MS Satoko Nagata PhD PHN RN Reiko Okamoto PhD PHN RN Ruriko Suzuki PHN RN MS Emiko Kishi PhD PHN RN Michie Nomura DSN PHN RN Noriko Jojima PHN RN MS Masumi Nishida PhD PHN RN Keiko Koide PhD PHN RN Emiko Kusano PhD PHN RN Saori Iwamoto PhD PHN RN Sachiyo Murashima PhD PHN RN 《Public health nursing (Boston, Mass.)》2015,32(6):654-661
2.
3.
Oral Everolimus for Treatment of a Giant Left Ventricular Rhabdomyoma in a Neonate—Rapid Tumor Regression Documented by Real Time 3D Echocardiography 下载免费PDF全文
Robert Wagner M.D. Ph.D. Frank Thomas Riede M.D. Hiroshi Seki M.D. Frauke Hornemann M.D. Steffen Syrbe M.D. Ingo Daehnert M.D. Ph.D. Michael Weidenbach M.D. Ph.D. 《Echocardiography (Mount Kisco, N.Y.)》2015,32(12):1876-1879
The presented case reports on successful treatment with everolimus in a neonate with left ventricular giant rhabdomyoma. The authors used a different dosage regime compared to literature and documented rapid tumor regression by 3D echocardiography. 相似文献
4.
The effects of spironolactone (5% SYC-201G, a preparation developed for clinical use in acne vulgaris by Searle Yakuhin K.K.), which is known to have antiandrogenic effects by competitively inhibiting dihydrotestosterone at androgen receptor sites, was topically applied to the androgen stimulated sebaceous glands of adult female golden hamsters. Androgen stimulation, induced by intramuscular injection of testosterone propionate (TP) every other day over a two week period, resulted in a 2.5 to 2.7 time increase in the size of the sebaceous glands of the hamster pinna. Once-daily treatment with 5% SYC-201G or matching placebo was applied to androgen-stimulated hamsters on one pinna only during the same period as TP injection. Comparison between the treated and untreated sides revealed a significant suppression in the sebaceous gland size (p<0.05) by 5% SYC-201G; no such effect was observed with placebo. The difference in the suppression rate of the sebaceous gland size between 5% SYC-201G (23%) and matching placebo (–4.7%) was significant (p<0.01). 相似文献
5.
6.
We report an 80-year-old Japanese male with four primary malignant tumors: malignant melanoma, prostatic cancer, malignant lymphoma, and renal cell carcinoma, which occurred in that respective order. The combination of malignant melanoma and malignant lymphoma is rare. The patient was treated with BCG after an operation for malignant melanoma. He was also treated with cobalt 60 irradiation after an operation for prostatic cancer. We also discuss other reports of multiple malignant tumors and suggest some possible causes of this patient's primary malignant tumors. 相似文献
7.
Y Imamura K Yanagihara Y Fukuda Y Kaneko M Seki K Izumikawa Y Miyazaki Y Hirakata T Sawa J P Wiener-Kronish S Kohno 《The European respiratory journal》2007,29(5):965-968
Pseudomonas aeruginosa is one of the most important pathogens in patients with chronic airway conditions, such as cystic fibrosis and diffuse panbronchiolitis. Type III secretion system-mediated virulence factors contribute to the lung damage in chronic P. aeruginosa infection. The effects of the anti-PcrV immunoglobulin (Ig)G, which blocks the type III secretion system, were evaluated in a mouse model of chronic P. aeruginosa infection. On bacteriological examination, anti-PcrV IgG showed no bactericidal effects. On bronchoalveolar lavage fluid (BALF) analysis, total cell number and neutrophil ratios in the anti-PcrV IgG-treated groups were lower than those in the control group. In addition, macrophage inflammatory protein-2, tumour necrosis factor-alpha, and interleukin-beta concentrations in BALF were lower in the anti-PcrV IgG-treated groups when compared with controls. Plasma anti-PcrV IgG titre was elevated after administration of anti-PcrV IgG. Although plasma titre decreased gradually, a significant concentration was maintained during the experimental period. These data suggest that anti-PcrV immunoglobulin G reduces the inflammatory reaction caused by chronic Pseudomonas aeruginosa respiratory infection and may be useful in treating respiratory diseases. 相似文献
8.
Nagai Masahiro Nishikawa Noriko Yabe Hayato Moritoyo Hiroyoko Moritoyo Takashi Shigematsu Yuji Nomoto Masahiro 《Journal of neurology》2007,254(4):IV54-IV57
Journal of Neurology - A high incidence of valvular heart disease in Parkinson's disease (PD) patients treated with ergot-derived dopamine agonists, such as cabergoline and pergolide, has been... 相似文献
9.
10.
Noriko Yoshimura Tomoko Takijiri Hirofumi Kinoshita Shigeto Danjoh Takahiro Kasamatsu Seiji Morioka Kiyomi Sakata Tsutomu Hashimoto Tatsuya Takeshita 《Osteoporosis international》2004,15(2):139-144
The aim of this study was to clarify and compare the temporal course of bone mineral density (BMD) between fast bone losers and normal residents in Miyama Village, a rural Japanese community. BMD was measured over a 10-year period in a cohort study in Miyama Village, Wakayama Prefecture, Japan, to provide information on rate of bone loss in the mature and elderly population. Subjects (n=400) were selected by sex and age stratum from the full list of residents born in 1910–1949, with 50 men and 50 women in each age decade. Baseline BMD of the lumbar spine and proximal femur was measured using dual energy X-ray absorptiometry in 1990, 1993, 1997 and 2000. In the cohort, 171 men and 189 women completed the follow-up survey performed in 1993. After calculating the rate of bone loss between 1990 and 1993, the greatest tertile from the distribution of bone loss was categorized as fast bone losers, with the remainder considered as normal subjects. Changes in BMD were compared between normal subjects and fast bone losers over the 10-year period. Mean rate of change for BMD at both lumbar spine and femoral neck in fast bone losers recovered to levels similar to those in normal subjects over 7 years of observation. By contrast, BMD at the lumbar spine and femoral neck decreased steeply over the 10-year period in both groups, and mean BMD for fast bone losers was significantly lower than that of normal subjects (P<0.05). These differences were apparent only at the lumbar spine in both men and women, even after adjusting for age. These results indicate that fast bone loss is a transient phenomenon rather than a fixed status, although individuals who have been categorized as fast bone losers at some stage continue to display low BMD in the lumbar spine. 相似文献