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排序方式: 共有296条查询结果,搜索用时 31 毫秒
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I A Shevelev N A Lazareva G A Sharaev R V Novikova A S Tikhomirov 《Neirofiziologiia》1987,19(2):179-185
The preservation of the effect of dynamic scanning of a part of the orientation diapason during development of neuron responses in the primary visual cortex of cat was examined after equalization of their latencies and after estimation of only highly significant fragments of their reactions. It was found that this effect was preserved in 13 neurons out of 17 examined ones: it remained invariable in 7 units of this group and was modified due to a shift of the scanning beginning along the diapason of orientations, to an increase of scanning diapason or to a change of scanning direction. The stabilization of the orientational tuning occurred only in 4 cells after equalization of latencies. The obtained results confirm that the dynamic changes of orientation tuning in the majority of visual cortex neurons are connected with reorganization of the time pattern of the reaction, as suggested by the hypothesis of the spatial-temporal orientation coding in the visual system. 相似文献
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L T Malaia I K Kondakov S A Lazareva L L Simirenko T K Bondar' 《Terapevticheski? arkhiv》1986,58(1):29-33
A study of the effect of the main risk factors of atherosclerosis in coronary patients on the prevalence of lipoidosis and prelipid changes in the aortal intima showed a week interrelationship between the studied risk factors and prevalence of lipoidosis. A noticeable significant interrelationship of the prevalence of prelipid changes in the aortal intima, patient's age, the IRI level and alpha-XC concentration in the blood plasma was established. An equation was described. A nomogram was presented permitting determination of the prevalence of prelipid changes in the aortal intima and, consequently, the phase of a course of atherosclerosis during the patient's lifetime on the basis of the above risk factors. 相似文献
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路路通内酯的化学结构 总被引:4,自引:1,他引:3
用红外,质谱,1H,13CNMR和1H-13CCOLOC等光谱解析,确定了新化合物路路通内酯的结构为3-羰基-11α,12α-环氧-13β-氧-齐墩果-28β-酸-13,28-γ-内酯,命名为路路通内酯。 相似文献
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Changes in the duration of the Achilles reflex were studied in subclinical disturbances of thyroid function. For this purpose the duration of the Achilles reflex, the levels of T4, T3, iodine protein bound TSH and cholesterol were investigated in children admitted to hospital with the general diagnosis of the "euthyroid goiter". Clinical and laboratory findings revealed subclinical types of the diffuse toxic goiter, hypothyrosis, chronic thyroiditis, endemic goiter, nodular goiter, pubertal struma and sporadic euthyroid goiter. The aim of the study was to define the diagnostic importance of reflexometry in subclinical disorders of thyroid function and to assess the relationships between metabolic derangements and the duration of the Achilles reflex. Changes in the duration were shown to correspond to disorder of thyroid function. In 76% of the cases reflexometry brought about the correct assessment of the patient's thyroid status. A significant conformity of the levels of TSH, T3, T4 to the duration of the Achilles reflex was shown. 相似文献
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M. Yu. Stepanichev M. V. Onufriev A. K. Piskunov Yu. V. Moiseeva N. A. Lazareva A. G. Moiseenok P. V. Gusev N. V. Gulyaeva 《Neurochemical Journal》2013,7(2):144-149
In this study, the effects of interoceptive stress on the indices of free-radical oxidation and the corticosterone contents in the brain and blood of male rats were examined. In addition, we studied the effects of the GABA-like nootropic drug calcium hopanthenate and panthenol on these indices after stress. Interoceptive stress was induced by intraperitoneal injection of bacterial lipopolysaccharide and the studies were performed 24 h after injection. The derivatives of pantothenic acid substantially attenuated corticosterone accumulation in the hippocampus after interoceptive stress induced by systemic immune challenge but did not prevent a stress-induced increase in the level of substances that reacted with thiobarbituric acid in the blood of the animals. 相似文献
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Giorgio Ottaviano Giovanna Lucchini Judith Breuer Juliana M. Furtado-Silva Arina Lazareva Oana Ciocarlie Reem Elfeky Kanchan Rao Persis J. Amrolia Paul Veys Robert Chiesa 《British journal of haematology》2020,188(4):560-569
Viral respiratory infections (VRIs) contribute to the morbidity and transplant-related mortality (TRM) after allogeneic haematopoietic stem cell transplantation (HSCT) and strategies to prevent and treat VRIs are warranted. We monitored VRIs before and after transplant in children undergoing allogeneic HSCT with nasopharyngeal aspirates (NPA) and assessed the impact on clinical outcome. Between 2007 and 2017, 585 children underwent 620 allogeneic HSCT procedures. Out of 75 patients with a positive NPA screen (12%), transplant was delayed in 25 cases (33%), while 53 children started conditioning with a VRI. Patients undergoing HSCT with a positive NPA screen had a significantly lower overall survival (54% vs. 79%) and increased TRM (26% vs. 7%) compared to patients with a negative NPA. Patients with a positive NPA who delayed transplant and cleared the virus before conditioning had improved overall survival (90%) and lower TRM (5%). Pre-HSCT positive NPA was the only significant risk factor for progression to a lower respiratory tract infection and was a major risk factor for TRM. Transplant delay, whenever feasible, in case of a positive NPA screen for VRIs can positively impact on survival of children undergoing HSCT. 相似文献
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