Harmful cyanobacteria blooms are increasing. They call for novel removal technology, since the required doses of algaecides may cause further environmental pollution or damage treatment facilities. Undesirable intracellular compounds can be released in the water when cyanobacterial cells are damaged. For the first time, ultrasound irradiation was combined with TiO2/biochar (TiO2/BC) at relatively low dosage and tested as an alternative for promoting the coagulation of Microcystis aeruginosa in water treatment. This pre-oxidation process removed 92% of cyanobacterial cells after coagulation. With the combination of ultrasound and TiO2/BC treatment, the dissolved organic carbon and microcystins levels did not increase significantly. The oxidative treatments enhanced the permeability of the cyanobacterial cell membranes, which may be due to the various active species generated from the ultrasound and TiO2/BC process. The results showed that the TiO2/BC hybrid catalyst could be a potential candidate for cyanobacterial cells removal in water.Ultrasound irradiation was combined with TiO2/biochar (TiO2/BC) at relatively low dosage to promote the coagulation of Microcystis aeruginosa.相似文献
Racial/ethnic disparities in breast cancer outcomes may be related to quality of care and reflected in emergency department (ED) visits following primary treatment. We examined racial/ethnic variation in ED visits following breast cancer surgery.
Methods
Using linked data from the California Cancer Registry and California Office of Statewide Health Planning and Development, we identified 151,229 women diagnosed with stage 0-III breast cancer between 2005 and 2013 who received surgical treatment. Differences in odds of having at least one breast cancer-related ED visit within 90 days post-surgery were estimated with logistic regression controlling for clinical and sociodemographic variables. Secondary analyses examined health care-related moderators of disparities.
Results
Hispanics and non-Hispanic (NH) Blacks had an increased likelihood of having an ED visit within 90 days of surgery compared to NH Whites [OR?=?1.11 (1.04–1.18), p?=?0.0016; OR?=?1.38 (1.27–1.50), p?<?0.0001, respectively]; the likelihood was reduced in Asian/Pacific Islanders [aOR?=?0.77 (0.71–0.84), p?<?0.0001]. Medicaid and Medicare (vs. commercial insurance) increased the likelihood of ED visit for NH Whites, and to a lesser degree for Hispanics and NH Blacks (p?<?0.0001 for interaction). Receipt of surgery at an NCI-designated Comprehensive Cancer Center or at a for-profit (vs. non-profit) hospital was associated with reduced likelihood of ED visits for all groups.
Conclusion
Racial/ethnic disparities in ED visits following breast cancer surgery persist after controlling for clinical and sociodemographic variables. Improving quality of care following breast cancer surgery could improve outcomes for all groups.
Danshen Injection, the aqueous extracts of Radix Salvia miltiorrhiza (S. miltiorrhiza), is one of the most commonly used traditional Chinese herbs in chronic renal failure treatment. In present study, the mechanism of the renoprotective effect of Danshen Injection was analyzed on streptozocin (STZ)-induced diabetic rats.
Materials and methods
Diabetic experimental model was established in male Sprague-Dawley (SD) rats by intraperitoneal injection of STZ. Rats with blood glucose concentration of higher than 300 mg/dl were intraperitoneally administered with Danshen Injection at a dose of 0.78 ml/kg day. The blood glucose, 24 h urinary protein excretion, serum creatinine (sCr), blood urea nitrogen (BUN), advanced glycation end products (AGEs), lipid peroxide (LPO), antioxidant enzyme of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), transforming growth factor-β1 (TGF-β1), and histomorphological changes in kidney of diabetic rats were analyzed during the course of Danshen Injection administration, as well as the tubular function index of albumin reabsorption of fluorescein isothiocyanate labeled bovine serum albumin (FITC-BSA).
Results
The intraperitoneal administration of Danshen Injection could ameliorate the physiological dysfunctions of increased 24 h urinary protein excretion((48.21±8.04)%), sCr((39.4±3.7)%), and BUN((43.37±6.74)%), alleviate the ultrastructural abnormalities of hypertrophy, matrix expansion, and fibrosis in glomerulus, decrease the TGF-β1 expression, AGEs and LPO accumulation, and increase the activity of SOD and GSH-Px in kidney of diabetic rats, but did not significantly influence the blood glucose. Besides these, the Danshen Injection administration also partly restored the decrease of megalin expression in tubules and reabsorptive function of FITC-BSA, in diabetic rats.
Conclusion
The renoprotection of Danshen Injection on diabetic rats was associated with the preservation of tubular function and structure from the hyperglycemia induced toxicities of inappropriate cytokines secretion, oxidative stress, advanced glycation stress, and megalin expression deletion. 相似文献