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排序方式: 共有1478条查询结果,搜索用时 31 毫秒
1.
LIU Haifeng LUO Zhenkun ZHANG Jian 《美国中华健康卫生杂志》2005,8(3):66-68
In this paper, the characteristics and regularities of acute ocular injuries by direct laser exposure are briefly reviewed, typical cases of ocular injuries from accidental laser exposure are reported, and laser occupational harm to the eye are discussed on the basis of epidemic investigation of personnel engaged in laser work. 相似文献
2.
LI Wei-yong LI Qian QIAO Jian DENG Jun-gang ZHANG Ying 《中国临床药理学与治疗学》2007,12(10):1182-1183
AIM: To determine the safety, tolerability and pharmacokinetic parameters of a new drug recombinant human parathyroid hormone [ rhPTH (1-84)] in healthy male Chinese subjects. METHODS: domly divided Thirty-six healthy male volunteers were rangroups received into 3 groups. The volunteers in these single subcutaneous injection of rhPTH ( 1-84) in a dosage of 1, 2 and 4 μg/kg respectively. Blood samples were obtained before and after administration within 24 hours. The rhPTH concentrations in sennn were determined by enzyme linked immunosorbent assay (ELISA). The pharmacokinetic parameters determined with use of standard noncompartmental analysis were the maximum serum concentration ( Cmax ), the time to attain that concentration ( tmax ), and the area under the serum concentration-time curve up to 24 hours( AUC0-24 ) and up to infinity (AUC0-∞). Dose proportionality of pharmacokinetic parameters (AUC, Cmax of every volunteer of each dosage and A UC was computed from log transformed data) and was examined by mean of analysis of variance (ANOVA) using SPSS software package. In the study, subjects' symptoms, objective signs, and vital signs, including blood pressure, heart rate, respiratory rate and body temperature, were checked and 12-lead electrocardiography was recorded before and after drug administration within 24 hours. Routine laboratory tests, including hematology, blood biochemistry, serum electrolyte, and urinalysis, were performed before and after drug administration within at 24 hours.[第一段] 相似文献
3.
4.
Tang Jian汤健 Wang Yu王瑜 Zkang Chenhui张晨晖 E. Costa Institute of Cardiovascular Research Beijing Medical University 《北京大学学报(医学版)》1994,(Z1)
THECLONINGOFNa ̄+/Ca ̄(2+)EXCHANGERGENEANDITSEXPRESSIONINBRAINISCHEMIATangJian汤健,WangYu王瑜,ZkangChenhui张晨晖,E.CostaInstituteofCar... 相似文献
5.
LIU Qi JIA YuChen TIAN JianMing WANG ZhenTang YE Hua YANG JiJin SUN Fei 《World journal of gastroenterology : WJG》1997,(4)
AcomparativestudyofdiferentinterventionaltherapiesforprimarylivercancerLIUQi,JIAYuChen,TIANJianMing,WANGZhenTang,YEHua,YA... 相似文献
6.
卢建 《国外医学:遗传学分册》1994,17(2):102-107
遗传性膜受体病主要系编码膜受体的基因空变使受体缺失,减少或结构异常,进而引起膜受体的功能障碍所致。目前,已报道的膜受体病已近10种,该类疾病发生的分子机制十分复杂,其基因突变呈明显的异质性。本文将目前研究较为深入的几种膜受体病做一简介。 相似文献
7.
Guan Xinmin Zhang Jian Shi Bo** Ouyang Xingbiao Research Department of Acupuncture Anesthesia Mechanism & Department of Neurobiology Tongji Medical University Wuhan China Department of Physiology Jinzhou School of Health Jinzhou Liaoning Province China 《世界针灸杂志》1993,(1)
For investigating the effect of acupuncture on ischemic arrhythmia and its mech-anism, adult albino rats with ligated anterior descending branch of coronary artery as experimentalmodel were treated with or without acupuncture, and others with imitative operation but without bothcoronary artery ligation and acupuncture treatment were used as control. It was found in acupuncturegroup that the fibrillation-liability of ischemic myocardium was efficiently decreased, the affinity ofAch-M receptors on membranes of ischemic myocardium was markedly increased, and the tolerance ofischemic myocardium to atropine was elevated in the experiment of atropine inducing fibrillation.These results indicate that acupuncture may play a therapeutic role on ischemic arrhythmia throughactivating the activity of muscarine-like receptors of cholinergic nervous system. 相似文献
8.
QIN Jian LIU Hong-jian DENG Wei WU Guo-zhen CHEN Shu-qing JING Ming-hua 《中国生物医学工程学报(英文版)》2005,14(3):114-119
Based on the fuzzy characteristic of the pulse state and syndromes differentiation thinking mode of TCM, an information fusing recognition method of pulse states based on SFNN (Stochastic Fuzzy Neural Network) is presented in this paper. With the learning ability in parameters and structure, SFNN fuses the measurement information of three pulse-state sensors distributed in Cun, Guan, and Chi location of body for the pulse state recognition. The experimental results show that the percentage of correct recognition with new method is higher than that by single-data recognition one, with fewer off-line train numbers. 相似文献
9.
Androgenplaysanimportantroleinthenormaldevelopmentofmalephenotypeandtheregulationofvirilization.Theseactionsofandrogenaremediatedbytheintracellularandrogenreceptor(AR)containingN--terminal,DNAuandsteroidbindingdomains.MutationsintheARgenecancausevariousdegreesofandrogenInsensitivitysyndromes(AlS)inpatientswith46,XYkaryotype.ThephenotypeofpatientswithAlSrangesfromcompletefemaleexternalgenitalia(completeAlS,CAIS)overgenitalambiguity(partialAlS,PAlS)totheinfertilewithnormalmaleornearlys… 相似文献
10.
遗传性膜受体病主要系编码膜受体的基因突变使膜受体缺失、减少或结构异常,进而引起膜受体的功能障碍所致。目前,已报道的膜受体病已近10种。该类疾病发生的分子机制十分复杂,其基因突变呈明显的异质性。本文将目前研究较为深入的几种膜受体病做一简介。 相似文献