全文获取类型
收费全文 | 3799篇 |
免费 | 149篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 120篇 |
儿科学 | 68篇 |
妇产科学 | 161篇 |
基础医学 | 488篇 |
口腔科学 | 53篇 |
临床医学 | 250篇 |
内科学 | 558篇 |
皮肤病学 | 277篇 |
神经病学 | 346篇 |
特种医学 | 124篇 |
外科学 | 610篇 |
综合类 | 9篇 |
预防医学 | 143篇 |
眼科学 | 129篇 |
药学 | 211篇 |
中国医学 | 13篇 |
肿瘤学 | 402篇 |
出版年
2023年 | 15篇 |
2022年 | 44篇 |
2021年 | 44篇 |
2020年 | 22篇 |
2019年 | 61篇 |
2018年 | 43篇 |
2017年 | 60篇 |
2016年 | 65篇 |
2015年 | 126篇 |
2014年 | 119篇 |
2013年 | 133篇 |
2012年 | 303篇 |
2011年 | 337篇 |
2010年 | 146篇 |
2009年 | 133篇 |
2008年 | 369篇 |
2007年 | 352篇 |
2006年 | 333篇 |
2005年 | 319篇 |
2004年 | 293篇 |
2003年 | 216篇 |
2002年 | 133篇 |
2001年 | 38篇 |
2000年 | 48篇 |
1999年 | 32篇 |
1998年 | 13篇 |
1997年 | 12篇 |
1996年 | 18篇 |
1995年 | 6篇 |
1994年 | 11篇 |
1993年 | 8篇 |
1992年 | 14篇 |
1991年 | 15篇 |
1990年 | 16篇 |
1989年 | 11篇 |
1988年 | 7篇 |
1987年 | 5篇 |
1986年 | 5篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1981年 | 2篇 |
1980年 | 3篇 |
1979年 | 4篇 |
1975年 | 3篇 |
1974年 | 6篇 |
1973年 | 7篇 |
1972年 | 2篇 |
1971年 | 1篇 |
1968年 | 1篇 |
1964年 | 1篇 |
排序方式: 共有3962条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
J-L Chabernaud 《Archives de pédiatrie》2005,12(4):477-490
The need for resuscitation of a distressed newborn in delivery room is more and more easily predictable. The two principal reasons are improvement of obstetrical survey and best perinatal regionalisation. Perinatal asphyxia and premature labour, especially before 32 weeks of gestational age, are the more frequent situation needing resuscitation at birth. A good survey of pregnancy and labor, verification of availability and efficiency of care devices and material in the delivery room are essential. In all guidelines respiratory resuscitation is today the priority in the first minutes. Non invasive positive pressure ventilation and early use of exogenous surfactant are the recent advances for the care of very premature baby in delivery room. Having a neonatal ventilator and pulse oximetry monitoring is recommended and can improve results. For the pregnant woman and the baby, maternal transfer if no contra-indications exist and when it is possible, is preferred to postnatal transportation in case of very premature labor or high risk pregnancy. In all the other situations neonatal transport must be strictly organised and realised by well-trained pediatric team, with adapted material and in the best conditions for security and comfort. The goal is to prevent any rupture until arrival in the referring neonatal intensive car unit. 相似文献
5.
6.
7.
The development of in vitro blood tests that measure the delayed hypersensitivity reaction developed after contact with Mycobacterium tuberculosis will change progressively the diagnosis of M. tuberculosis infection. These blood assays (Quantiferon TB Gold, Cellestis, Australia; T-SPOT.TB, Oxford Immunotec, United Kingdom) use specific, complex M. tuberculosis antigens (ESAT-6 and CFP-10), whereas the intra-dermal Mantoux test is done with tuberculin, a complex mixture of more than 200 antigens. ESAT-6 and CFP-10 are absent from all the BCG vaccine strains used throughout the world. Significant improvement in the specificity with equivalent or increased sensitivity of the in vitro tests compared to the Mantoux test will lead eventually to replacement of the latter. 相似文献
8.
Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. 总被引:13,自引:0,他引:13
Kon Chu Sang-Wuk Jeong Keun-Hwa Jung So-Young Han Soon-Tae Lee Manho Kim Jae-Kyu Roh 《Journal of cerebral blood flow and metabolism》2004,24(8):926-933
The selective cyclooxygenase-2 (COX-2) inhibitor has been reported to have antiinflammatory, neuroprotective, and antioxidant effects in ischemia models. In this study, the authors examined whether a selective COX-2 inhibitor (celecoxib) reduces cerebral inflammation and edema after intracerebral hemorrhage (ICH), and whether functional recovery is sustained with longer treatment. ICH was induced using collagenase in adult rats. Celecoxib (10 or 20 mg/kg) was administered intraperitoneally 20 minutes, 6 hours, and 24 hours after ICH and then daily thereafter. Seventy-two hours after ICH induction, the rats were killed for histologic assessment and measurement of brain edema and prostaglandin E2. Behavioral tests were performed before and 1, 7, 14, 21, and 28 days after ICH. The brain water content of celecoxib-treated rats decreased both in lesioned and nonlesioned hemispheres in a dose-dependent manner. Compared with the ICH-only group, the number of TUNEL-positive, myeloperoxidase-positive, or OX42-positive cells was decreased in the periphery of hematoma and brain prostaglandin E2 level was reduced in the celecoxib-treated group. Celecoxib-treated rats recovered better by the behavioral tests at 7 days after ICH throughout the 28-day period, and the earlier the drug was administered, the better the functional recovery. Evidence of similar effects in an autologous blood-injected model showed that direct collagenase toxicity was not the major cause of inflammation or cell death. These data suggest that celecoxib treatment after ICH reduces prostaglandin E2 production, brain edema, inflammation, and perihematomal cell death in the perihematomal zone and induces better functional recovery. 相似文献
9.
10.
OBJECTIVES: Little information is available to incoming students in pediatrics residency programs on the experiences of past residents. The objective of this study was to investigate the pediatrics training programs and determine the professional outcomes of graduating residents between 1990 and 2000 in the Western Interregion. POPULATION AND METHODS: Questionnaires were distributed to the 187 medical students enrolled in pediatrics residency programs between 1990 and 2000 in the six university hospital centers of the Western Interregion. The questions concerned the details of training, the modes of residency positions, and current professional and personal situations. One hundred and sixty-five (88%) individuals responded. RESULTS: Seventy-seven percent of the practicing pediatricians stated that the training they had received during residency was adapted to their current practice. This percentage was higher for hospital staff physicians (82%) than for the physicians in private practice (50%) or those with salaried positions outside the hospital system (58%). One hundred and twenty-four had either completed post-residency training (97) or were doing so (27) at the time of the survey. All but one were professionally active, three quarters of them in hospitals and, of these, most were in the hospitals where they had trained. Eighty-six percent of the practicing pediatricians said they were satisfied with their professional work and 73% said they were satisfied with their personal lives. CONCLUSION: These results support the current reflection on reforming the residency training program in pediatrics, especially with regard to its prolongation and the diversification of the training options to take into account the individual student's professional orientation. 相似文献