全文获取类型
收费全文 | 6745篇 |
免费 | 1030篇 |
国内免费 | 47篇 |
专业分类
耳鼻咽喉 | 124篇 |
儿科学 | 196篇 |
妇产科学 | 119篇 |
基础医学 | 617篇 |
口腔科学 | 124篇 |
临床医学 | 1496篇 |
内科学 | 1572篇 |
皮肤病学 | 207篇 |
神经病学 | 444篇 |
特种医学 | 212篇 |
外国民族医学 | 2篇 |
外科学 | 1105篇 |
综合类 | 80篇 |
预防医学 | 373篇 |
眼科学 | 208篇 |
药学 | 365篇 |
中国医学 | 94篇 |
肿瘤学 | 484篇 |
出版年
2024年 | 22篇 |
2023年 | 189篇 |
2022年 | 173篇 |
2021年 | 299篇 |
2020年 | 334篇 |
2019年 | 244篇 |
2018年 | 425篇 |
2017年 | 304篇 |
2016年 | 397篇 |
2015年 | 327篇 |
2014年 | 490篇 |
2013年 | 575篇 |
2012年 | 553篇 |
2011年 | 436篇 |
2010年 | 423篇 |
2009年 | 391篇 |
2008年 | 322篇 |
2007年 | 304篇 |
2006年 | 282篇 |
2005年 | 225篇 |
2004年 | 151篇 |
2003年 | 100篇 |
2002年 | 113篇 |
2001年 | 71篇 |
2000年 | 50篇 |
1999年 | 59篇 |
1998年 | 67篇 |
1997年 | 67篇 |
1996年 | 64篇 |
1995年 | 54篇 |
1994年 | 31篇 |
1993年 | 18篇 |
1992年 | 22篇 |
1991年 | 30篇 |
1990年 | 17篇 |
1989年 | 14篇 |
1988年 | 9篇 |
1987年 | 9篇 |
1986年 | 19篇 |
1985年 | 22篇 |
1984年 | 19篇 |
1983年 | 12篇 |
1982年 | 7篇 |
1980年 | 6篇 |
1978年 | 6篇 |
1976年 | 6篇 |
1975年 | 9篇 |
1973年 | 6篇 |
1955年 | 6篇 |
1949年 | 6篇 |
排序方式: 共有7822条查询结果,搜索用时 0 毫秒
1.
2.
Fibromyalgia is a syndrome of widespread pain, nonrestorative sleep, disturbed mood, and fatigue. Optimal treatment involves
a multidisciplinary approach with a team of health care providers using pharmacologic and nonpharmacologic treatment. Because
of the heterogeneity of the illness, management should be individualized for the patient. Pharmacologic treatment should address
issues of pain control, sleep disturbance, fatigue, and any underlying coexisting mood disorder. Nonpharmacologic treatment
should include patient education, a regular exercise and stretching program, and cognitive behavioral therapy. All of these
are essential to improving functional capacity and quality of life. This review provides general guidelines in initiating
a successful pharmacologic treatment program for patients with fibromyalgia. 相似文献
3.
Zia Hossein Ma Joseph K. H. O'Donnell John P. Luzzi Louis A. 《Pharmaceutical research》1991,8(4):502-504
Dimethyl isosorbide (DMI), which is currently under investigation for its potential use as a pharmaceutical vehicle and drug permeation enhancer, is a water-miscible liquid with relatively low viscosity. The solubilization behavior of DMI as a cosolvent for nonpolar drugs was characterized via dielectric constant measurements of binary solvent systems containing DMI and either water, propylene glycol (PG), or polyethylene glycol (PEG). Evidence from the dielectric constant profiles and NMR studies suggest that DMI undergoes complexation with water and PG, but not with PEG, through hydrogen bonding interactions. The solvent complexation exhibited a major effect on the solubilities of prednisone, dexamethasone, and prednisolone in the mixed solvent systems. Maximum solubility of each drug was found to occur near a DMI/water or DMI/PG concentration ratio of 1:2. In the DMI–PEG mixed system, while there is no apparent interaction between DMI and PEG molecules, the solubility of prednisone was found to increase with decreasing dielectric constant. 相似文献
4.
5.
Alfred Philip James Lake BSc MBBS FFARCS ; Kathiravelpillai Puvanachandra MBBS DO FRCS FRCOphth 《Pain practice》2004,4(2):130-131
Abstract: Stellate ganglion block is commonly used to treat the sympathetically maintained pain which may occur in one‐third of patients with complex regional pain syndrome type 1. A complication that followed a single block and presented a diagnostic dilemma for the ophthalmologist is reported. 相似文献
6.
7.
LESLEY BOULTON MB CHB FRACO DO Ophthalmologist 《Clinical & experimental ophthalmology》1986,14(4):365-371
The Low Vision Clinic at the Palmerston North Hospital has now been oerating for 70 years. Over the course of these ten years a number of factors have emerged which can be as readily applied to general ophthalmological practice as to low vision practice. The philosophy of low vision care is one of which all ophthalmologists should be aware and includes factors to be taken into account when dealing with children, people in the workplace, and everyday factors involved in daily living activities, all of which are equally relevant in routine ophthalmological practice. This paper endeavours to share some thoughts on these factors and also discusses means by which the visually handicapped can be helped in areas where specialist low vision services are not readily available. 相似文献
8.
Peter R. McNally DO John C. Lemon MD John S. Goff MD Stephen R. Freeman MD 《Digestive diseases and sciences》1993,38(2):369-373
Summary A case of a 31-year-old female with congenital esophageal stenosis presenting with symptoms of chest pain caused by esophageal dysmotility is described. The involved segment in congenital esophageal stenosis has a characteristic thickening of the muscularis propria layer, as seen by EUS examination. In these patients, symptoms of dysphagia can be managed with esophageal dilation and noncardiac esophageal chest pain responds to pharmacotherapy with diltiazem.The opinions and assertions contained herein are the private ones of the authors and are not to be construed as official policy or reflecting the views of the Army or the Department of Defense. 相似文献
9.
Mark Ellis FRACO FRACS Ross Drewe MB BS DO † Justin O'Day FRACO FRACS 《Clinical & experimental ophthalmology》1994,22(2):119-123
Desmoplastic malignant melanoma (DMM) is a rare variant of spindle cell melanoma. We report a case of DMM of the forehead secondarily involving the orbit. The diagnosis was based on light microscopic features, including prominent peripheral cell nest formation and spindle cell fascicles in densely collagenous stroma. Immunohistochemical studies showed strong uniform staining for S100 antigen throughout the tumour. It was negative for HMB 45, smooth muscle actin, desmin, cytokeratins and Type IV collagen. Electron microscopy showed neither melanosomes nor myelin figures. The clinical and histological characteristics of desmoplastic malignant melanoma, and its differential diagnosis of malignant schwannoma, are discussed. DMM has a poor prognosis, since it tends to invade deeply, recur locally and metastasise readily. 相似文献
10.
BACKGROUND CONTEXT: Paraspinal infections after zygapophyseal (facet) radiofrequency denervation (RFD) are a serious but rare complication of this procedure. We are aware of only one case report of an epidural abscess after facet joint injection. PURPOSE: To report post-procedure inflammatory changes after cervical facet RFD. STUDY DESIGN: Case report. PATIENT SAMPLE: A 35-year-old Caucasian female. METHODS: Retrospective case review. RESULTS: The patient underwent cervical RFD and was admitted to the hospital 7 days after her procedure with severe neck pain. Magnetic resonance imaging (MRI) with contrast revealed what appeared to be evidence of a paraspinal muscle abscess although blood tests were negative. She was treated with antibiotic therapy, yet she never developed systemic signs of infection. A follow-up MRI without contrast revealed no evidence of infection, and she was discharged home on hospital day 6. At her first follow-up visit, she was still experiencing scalp pain and paraspinal muscle spasm. During subsequent follow-up visits, she has continued to improve clinically without experiencing signs of infection. Another follow-up MRI 6 weeks after her discharge home revealed persistent minimal left paraspinal enhancement at C2-3, possibly representing post-procedure granulation tissue with no evidence of abscess. CONCLUSIONS: Post-procedural MRI findings after radiofrequency lesioning can resemble radiographic findings associated with a paraspinal abscess. Patients with radiographic findings consistent with abscess should only be treated if clinical signs or symptoms of systemic infection are present. 相似文献