全文获取类型
收费全文 | 8365篇 |
免费 | 686篇 |
国内免费 | 11篇 |
专业分类
耳鼻咽喉 | 107篇 |
儿科学 | 240篇 |
妇产科学 | 202篇 |
基础医学 | 1092篇 |
口腔科学 | 185篇 |
临床医学 | 1123篇 |
内科学 | 1662篇 |
皮肤病学 | 103篇 |
神经病学 | 887篇 |
特种医学 | 384篇 |
外国民族医学 | 4篇 |
外科学 | 800篇 |
综合类 | 89篇 |
预防医学 | 865篇 |
眼科学 | 243篇 |
药学 | 686篇 |
中国医学 | 6篇 |
肿瘤学 | 384篇 |
出版年
2022年 | 54篇 |
2021年 | 113篇 |
2020年 | 79篇 |
2019年 | 134篇 |
2018年 | 129篇 |
2017年 | 96篇 |
2016年 | 130篇 |
2015年 | 148篇 |
2014年 | 213篇 |
2013年 | 299篇 |
2012年 | 440篇 |
2011年 | 474篇 |
2010年 | 247篇 |
2009年 | 260篇 |
2008年 | 416篇 |
2007年 | 469篇 |
2006年 | 404篇 |
2005年 | 415篇 |
2004年 | 350篇 |
2003年 | 366篇 |
2002年 | 322篇 |
2001年 | 242篇 |
2000年 | 218篇 |
1999年 | 191篇 |
1998年 | 91篇 |
1997年 | 64篇 |
1996年 | 66篇 |
1994年 | 80篇 |
1993年 | 58篇 |
1992年 | 138篇 |
1991年 | 155篇 |
1990年 | 162篇 |
1989年 | 173篇 |
1988年 | 140篇 |
1987年 | 114篇 |
1986年 | 125篇 |
1985年 | 113篇 |
1984年 | 99篇 |
1983年 | 68篇 |
1982年 | 50篇 |
1980年 | 52篇 |
1979年 | 80篇 |
1978年 | 79篇 |
1977年 | 62篇 |
1975年 | 52篇 |
1974年 | 58篇 |
1973年 | 68篇 |
1972年 | 70篇 |
1971年 | 54篇 |
1967年 | 50篇 |
排序方式: 共有9062条查询结果,搜索用时 15 毫秒
1.
Antonia Zapf Marianne Huebner Geraldine Rauch Meinhard Kieser 《Statistics in medicine》2019,38(4):695-701
Biostatisticians play an important role in medical research. They are co-responsible for an appropriate and efficient study design, they are involved in monitoring the study conduct, they plan and perform the data analysis, and they are involved in interpreting and publishing the results. However, how are the biostatisticians prepared for their tasks and responsibilities? Graduate programs in biostatistics are being offered, but some practicing biostatisticians completed their studies in a mathematical or epidemiological program, or obtained their degree in subject-specific fields (such as medicine or biology). Therefore, the expertise and the competencies can vary widely between the individual biostatisticians, also depending on the application field. In this article, focusing on European and US practices, we discuss the required professional expertise for the main areas of applications in the medical field as well as the necessary soft skill competencies of a biostatistician. 相似文献
2.
3.
An educational intervention was developed to improve family practice residents' ability to obtain useful information from pharmaceutical representatives. The curriculum is based on the traditional one-on-one drug detail. The objectives are to develop residents' skills in controlling the interview, promote skills for critically analyzing drug-promotional material, and discuss ethical issues. The contents include an assessment tool, suggested readings, and interview questions with rationale. After 5 years, residents' confidence in all areas of the curriculum improved significantly. 相似文献
4.
5.
S H Jacobson 《Scandinavian journal of urology and nephrology》1991,25(1):51-57
Fifty women with pyelonephritic renal scarring were prospectively followed for five years and the changes in renal function were related to blood pressure control, plasma renin activity, urinary albumin excretion and the incidence of urinary tract infections (UTI). Five patients (10%) developed end stage renal disease. All these patients had bilateral disease, proteinuria and anti-hypertensive treatment at presentation. The mean +/- SD glomerular filtration rate (GFR) of all patients with renal scarring was 74 +/- 27 ml/min x 1.73 m2 at presentation which was significantly lower than the GFR in 55 patients with a recent episode of acute pyelonephritis (p less than 0.001) and 10 healthy controls (p less than 0.001). GFR and age corrected GFR decreased significantly during follow-up (p less than 0.001) and p less than 0.02 respectively). The decrease in GFR was significantly higher in patients with bilateral scarring, in patients on blood pressure treatment and in patients with an episode of symptomatic UTI during follow-up. Eight patients (16%) had antihypertensive treatment at presentation and another 11 patients (26%), of whom 10 had bilateral scarring, developed hypertension (greater than 140/90 mmHg) during follow-up. Seventy-five per cent of all patients had symptomatic UTI and 40% had an episode of acute pyelonephritis during follow-up. In conclusion, patients with pyelonephritic scarring have a high incidence of UTI and are at high risk of developing renal failure and hypertension. It is essential that recurrent episodes of symptomatic UTI are treated promptly and that blood pressure is monitored carefully in these patients. 相似文献
6.
Five agents are currently approved for the treatment of chronic hepatitis B infection. This article will discuss the three agents for which the most extensive data are available; interferon (IFN), lamivudine, and adefovir, while the following article by Dr. Jules Dienstag will discuss the recently marketed agents, entecavir and peginterferon alfa-2a. The advantages of IFN are its finite duration of therapy (4–6 months), lack of emergence of resistance, and durability of response. On the negative side, response to IFN is less durable in patients with HBeAg-negative chronic hepatitis B virus (HBV). Also, use of IFN is limited by adverse effects and the mode of administration (daily to thrice-weekly subcutaneous injection). Lamivudine and adefovir are orally administered and have good tolerability and safety. Even in patients who experience a marked decrease in serum HBV DNA and loss of HBeAg, oral therapy needs to be continued for at least 6 months, to avoid the risk of reappearance of HBeAg and viremia. Rates of HBeAg seroconversion to anti-HBe-positivity increase with duration of lamivudine or adefovir therapy. The likelihood of development of resistance to lamivudine and associated viral breakthrough limits its long-term use. In patients with HBeAg-negative chronic hepatitis B, long-term therapy is usually required, as off-treatment relapse is common. The emergence of resistance to adefovir is delayed and infrequent, hence adefovir may be preferred in patients requiring long-term therapy. 相似文献
7.
8.
J. Jacobson sen 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》1884,30(2):261-282
Ohne Zusammenfassung 相似文献
9.
10.
D L Jacobson B E Allman P J McMahon K A Nugent D Paganin M Arif S A Werner 《Applied radiation and isotopes》2004,61(4):547-550
In this paper, we will discuss a phase-contrast imaging method that avoids the complications of interferometry to provide phase contrast in weakly absorbing samples. A transversely coherent neutron beam is used with the traditional radiography scheme. Images taken with this scheme show dramatic intensity variations due to sharp changes in the neutron wave refractive index. With some numerical processing these images may be used to reconstruct a quantitative phase radiograph of specimens imaged with this technique. 相似文献