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排序方式: 共有751条查询结果,搜索用时 15 毫秒
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Neuroblastoma: the role of MR imaging 总被引:1,自引:0,他引:1
R B Dietrich H Kangarloo C Lenarsky S A Feig 《AJR. American journal of roentgenology》1987,148(5):937-942
Thirty-five MR examinations were performed in 17 children with neuroblastoma during the course of their diagnostic evaluation and treatment. Findings were confirmed by correlation with the results of other imaging techniques, biopsies, and surgical and autopsy findings. MR accurately detected the lesions and their extent in all patients. It correctly evaluated the possibility of resectability and showed metastases, response to treatment and development of complications. MR appears to be a reliable technique for the diagnosis, staging, and follow-up of children with neuroblastoma. 相似文献
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Inverse changes in erythroid cell volume and number regulate the hematocrit in newborn genetically hypertensive rats. 下载免费PDF全文
J W Boylan J B Van Liew P U Feig 《Proceedings of the National Academy of Sciences of the United States of America》1991,88(21):9848-9852
Erythrocytosis and microcytosis have been described in strains of genetically hypertensive rats and in essentially hypertensive humans. Published discussion of these phenomena has centered around their relationship to observed alterations in ionic transport and the pathogenesis of hypertension. In presenting data for another strain of spontaneously hypertensive rats in which these findings are exhibited, we note that erythroid cell size decreases concurrently with the increase in cell numbers so that the hematocrit and the mean corpuscular hemoglobin concentration remain constant. Data from the literature support the hypothesis that erythroid cell size is inversely proportional to cell count in a large number of species. Erythrocytosis, as it develops in the neonatal rat, is a consequence of the marked immaturity of this species at birth. Erythrocytosis in the spontaneously hypertensive rat is not due to a difference in the affinity of its hemoglobin for oxygen or to significant tissue anorexia. Microcytosis in the spontaneously hypertensive rat is the consequence of a continuation of the linear volume decrease with age of its erythroid cells seen in the normotensive animals and may be accounted for by the production of smaller cells with concomitant regulation of individual cell volume. 相似文献
6.
A unique case of familial hyperparathyroidism associated with carcinoma of the colon is presented. Two brothers presented initially with colonic carcinoma and years later both were found to have primary hyperparathyroidism on the basis of parathyroid hyperplasia. This raises the issue of associated malignancies in patients with hyperparathyroidism, especially if they are found to be familial. One member of the family developed severe, recurrent hypercalcemia with bone disease, and thus the need for continued follow-up is emphasized. 相似文献
7.
The electron microscopic autoradiographic tracing method has been used to examine the morphology and postsynaptic relationships of five projections (retina, cortical area 17, superior colliculus (tectal), parabigeminal nucleus, and pretectum) to the dorsal lateral geniculate nucleus of the greater bush baby galago crassicaudatus. Retinal terminals have been examined in the contralaterally innervated layer of each of the three matched pairs [parvi-(X-cell), magno- (Y--cell), and koniocellular (small, W-cell)] of geniculate layers. These terminals are large and contain pale mitochondria and round vesicles (RLPs). RLPs are presynaptic to juxtasomatic regions of parvi-and magnocellular neurons. In contrast, RLPs innervate more distal regions of konicellular neurons. Labeled cortical, tectal, and parabigeminal terminals are relatively small and contain round vesicles na dark mitochondria. Cortical terminals in each of the three representative layers are presynaptic to small diameter dendrites. No convergence of cortical and retinal terminals has been seen in any layer. Labeled tectal and parabigminal terminals are found primarily in the koniocellular layers, but the latter are also seen in all other layers. Tectal and parabigeminal terminals have been observed converging with retinal terminals on dendrites of some koniocellular neurons. Labeled pretectogeniculate terminals contain densely packed pleomorphic vesicles, dark mitochondria, and a dark cytoplasmic matric. These terminals, which are present in each of the representative layers, are presynaptic to conventional dendrites and profiles containing loosely despersed pleomorphic vesicles and a pale cytoplasmic matrix. © 1994 Wiley-Liss, Inc. 相似文献
8.
Kazumasa Fujitani Jaffer A. Ajani Christopher H. Crane Barry W. Feig Peter W. Pisters Nora Janjan Garrett L. Walsh Stephen G. Swisher Ara A. Vaporciyan David Rice Angela Welch Jackie Baker Josephine Faust Paul F. Mansfield MD 《Annals of surgical oncology》2007,14(4):1305-1311
Background Significant tumor downstaging has been achieved in patients with localized gastric or gastroesophageal adenocarcinoma by induction
chemotherapy and preoperative chemoradiotherapy (CTX–CTXRT). However, the influence of CTX–CTXRT on operative morbidity and
mortality has not yet been clarified. The aim of the present study was to document the frequency and nature of morbidity and
mortality after surgery combined with CTX–CTXRT, and identify factors predictive of postoperative complications in patients
with localized gastric or gastroesophageal adenocarcinoma.
Methods A prospectively collected database on 71 consecutive patients who underwent CTX–CTXRT at M.D. Anderson Cancer Center between
January 1997 and August 2004 was reviewed. Postoperative morbidity and mortality were investigated, and risk factors for overall
complications were identified by multivariate logistic regression analysis.
Results Overall morbidity and mortality rates were 38.0% (27 patients) and 2.8% (2 patients), respectively. Age greater than 60 years
[relative risk 11.3 (95% confidence interval 2.50–50.6)] and body mass index (BMI) of 26 kg/m2 or above [relative risk 4.08 (95% confidence interval 1.08–15.4)] were significant risk factors for overall complications.
Conclusions CTX–CTXRT can be performed safely with an acceptable operative morbidity and a low operative mortality rate in patients with
gastric or gastroesophageal cancer, with careful consideration of added risk associated with age and obesity. 相似文献
9.
Dr. David H. Berger MD Barry W. Feig MD Donald Podoloff MD James Norman MD C. Wayne Cruse MD Douglas S. Reintgen MD Merrick I. Ross MD 《Annals of surgical oncology》1997,4(3):247-251
Background: If cutaneous lymphoscintigraphy (CL) is accurate in predicting the draining lymph node basins at risk from primary axial
melanomas, then regional metastases should only occur in those lymph node basins identified by CL.
Methods: This study is a retrospective review of patients undergoing CL for primary axial melanomas from June 1, 1985, until June
31, 1992. Data retrieved included age, gender, number of basins identified, location of basins identified, management of basins,
recurrence in lymphatics, development of distant disease, and long-term follow-up.
Results: A total of 181 patients underwent elective LND, and 48 patients (27%) had melanoma in the nodes within the dissected basin.
Of these 181 patients, seven developed nodal metastases as their site of first recurrence. All seven recurrences were seen
at sites dissected or at sites indicated by CL, which the primary surgeon elected not to treat initially. Of the 116 patients
observed, 16 (14%) developed lymph node metastases as their first site of recurrence. Fifteen of these 16 patients had their
site of lymph node metastases predicted by CL. In this study, CL predicted 98.6% of all lymph node metastases.
Conclusions: The high overall reliability of CL as demonstrated by long-term follow-up indicates that the information obtained by CL can
be reliably used to guide intervention. Initial evaluation of patients with high-risk cutaneous melanomas at sites with ambiguous
lymphatic drainage must include CL in order to determine the draining lymph node basins and to plan therapy.
Presented at the 47th Annual Cancer Symposium of The Society of Surgical Oncology, Houston, Texas, March 17–20, 1994. 相似文献
10.
Women''s Health: Hormone replacement therapy for the primary prevention of chronic diseases: recommendation statement from the Canadian Task Force on Preventive Health Care 下载免费PDF全文