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排序方式: 共有182条查询结果,搜索用时 15 毫秒
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Elisa Veronese Roberto Stramare Andrea Campion Bernd Raffeiner Valeria Beltrame Elena Scagliori Alessandro Coran Luca Ciprian Ugo Fiocco Enrico Grisan 《Medical engineering & physics》2013,35(2):188-194
Rheumatoid arthritis (RA) is a chronic multisystemic autoimmune disease, with an unclear etiopathogenesis. Its early diagnosis and activity assessment are essential to adjust the proper therapy. Among the different imaging techniques, ultrasonography (US) allows direct visualization of early inflammatory joint changes as synovitis, being also rapidly performed and easily accepted by patients. We propose an algorithm to semi-automatically detect synovial boundaries on US images, requiring minimal user interaction. In order to identify the synovia-bone and the synovia-soft tissues interfaces, and to tackle the morphological variability of diseased joints, a cascade of two different active contours is developed, whose composition corresponds to the whole synovial boundary.The algorithm was tested on US images acquired from proximal interphalangeal (PIP) and metacarpophalangeal (MCP) finger joints of 34 subjects. The results have been compared with a consensus manual segmentation. We obtained an overall mean sensitivity of 85 ± 13%, and a mean Dice's similarity index of 80 ± 8%, with a mean Hausdorff distance from the manual segmentation of 28 ± 10 pixels (approximately 1.4 ± 0.5 mm), that are a better performance than those obtained by the raters with respect to the consensus. 相似文献
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Cozzi F Parisi G Ciprian L Bullo A Cardarelli S Rizzo M Sfriso P Punzi L 《Rheumatology international》2012,32(5):1219-1223
Gastric involvement appears quite commonly in systemic sclerosis (SSc). The aim of this study was to evaluate gastric wall
motility using ultrasonography, a noninvasive method able to track both filling and emptying of fundus and antrum. The study
was performed in 20 SSc patients and 20 healthy control subjects. Gastric filling and emptying were evaluated by transabdominal
ultrasonography, measuring changes in fundus and antral areas over a 1-h period after ingestion of a liquid bolus (500 ml
of mineral water). Areas of both gastric fundus and antrum at basal evaluation were found to be smaller in SSc patients than
in healthy controls. Gastric filling was significantly reduced after ingestion of liquid bolus. Gastric emptying was delayed
both in fundus and antrum. No significant differences of gastric wall motility have been observed in different subsets of
SSc patients. Our findings show that gastric dysmotility is frequent and severe in SSc patients, contributing to the gastrointestinal
disturbances which are very common in this disease. 相似文献
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We report the case of death of a 75-year-old Caucasian woman, produced by three different ways of mechanical asphyxia: smothering and strangulation by hand and traumatic asphyxia by thoracic compression. All these criminal offences were carried out by one single assailant who compressed the mouth and the nose of the victim with the left hand, squeezed her neck with the right hand and pressed her thorax with the knees. 相似文献
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Judenhofer MS Catana C Swann BK Siegel SB Jung WI Nutt RE Cherry SR Claussen CD Pichler BJ 《Radiology》2007,244(3):807-814
PURPOSE: To prospectively use compact avalanche photodiodes instead of photomultiplier tubes to integrate a positron emission tomographic (PET) detector and a 7-T magnetic resonance (MR) imager. MATERIALS AND METHODS: All animal experiments were performed in accordance with the University of Tübingen guidelines and the German law for the protection of animals. A compact lutetium oxyorthosilicate-avalanche photodiode PET detector was built and optimized to operate within a 7-T MR imager. The detector performance was investigated both outside and inside the magnet, and MR image quality was evaluated with and without the PET detector. Two PET detectors were set up opposite each other and operated in coincidence to acquire PET images in the step-and-shoot mode in a mouse head specimen after injection of fluorine 18 fluorodeoxyglucose. RESULTS: The performance of the PET detector when operated inside the magnet during MR image acquisition showed little degradation in energy resolution (increase from 14.6% to 15.9%). The PET detector did not influence MR imaging. The fused PET and MR images showed an anatomic match and no degradation of image quality. CONCLUSION: Simultaneous PET and MR imaging with a 7-T system was deemed feasible. 相似文献
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Korzeniewska A Crainiceanu CM Kuś R Franaszczuk PJ Crone NE 《Human brain mapping》2008,29(10):1170-1192
A new method (Event-Related Causality, ERC) is proposed for the investigation of functional interactions between brain regions during cognitive processing. ERC estimates the direction, intensity, spectral content, and temporal course of brain activity propagation within a cortical network. ERC is based upon the short-time directed transfer function (SDTF), which is measured in short EEG epochs during multiple trials of a cognitive task, as well as the direct directed transfer function (dDTF), which distinguishes direct interactions between brain regions from indirect interactions via brain regions. ERC uses new statistical methods for comparing estimates of causal interactions during prestimulus "baseline" epochs and during poststimulus "activated" epochs in order to estimate event-related increases and decreases in the functional interactions between cortical network components during cognitive tasks. The utility of the ERC approach is demonstrated through its application to human electrocorticographic recordings (ECoG) of a simple language task. ERC analyses of these ECoG recordings reveal frequency-dependent interactions, particularly in high gamma (>60 Hz) frequencies, between brain regions known to participate in the recorded language task, and the temporal evolution of these interactions is consistent with the putative processing stages of this task. The method may be a useful tool for investigating the dynamics of causal interactions between various brain regions during cognitive task performance. 相似文献
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