Author Keywords: chronic depression; clinical trial; dysthymia; medication treatment; serotonergic antidepressants 相似文献
全文获取类型
收费全文 | 2957篇 |
免费 | 253篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 43篇 |
儿科学 | 81篇 |
妇产科学 | 106篇 |
基础医学 | 418篇 |
口腔科学 | 48篇 |
临床医学 | 336篇 |
内科学 | 667篇 |
皮肤病学 | 64篇 |
神经病学 | 246篇 |
特种医学 | 86篇 |
外科学 | 376篇 |
综合类 | 11篇 |
一般理论 | 3篇 |
预防医学 | 307篇 |
眼科学 | 43篇 |
药学 | 174篇 |
中国医学 | 2篇 |
肿瘤学 | 207篇 |
出版年
2023年 | 61篇 |
2022年 | 84篇 |
2021年 | 199篇 |
2020年 | 117篇 |
2019年 | 147篇 |
2018年 | 141篇 |
2017年 | 99篇 |
2016年 | 98篇 |
2015年 | 113篇 |
2014年 | 141篇 |
2013年 | 154篇 |
2012年 | 248篇 |
2011年 | 220篇 |
2010年 | 92篇 |
2009年 | 76篇 |
2008年 | 158篇 |
2007年 | 143篇 |
2006年 | 122篇 |
2005年 | 105篇 |
2004年 | 120篇 |
2003年 | 108篇 |
2002年 | 78篇 |
2001年 | 41篇 |
2000年 | 37篇 |
1999年 | 27篇 |
1998年 | 17篇 |
1997年 | 19篇 |
1996年 | 16篇 |
1995年 | 13篇 |
1994年 | 11篇 |
1993年 | 6篇 |
1992年 | 10篇 |
1991年 | 9篇 |
1990年 | 7篇 |
1989年 | 11篇 |
1988年 | 16篇 |
1987年 | 12篇 |
1986年 | 13篇 |
1985年 | 12篇 |
1984年 | 12篇 |
1983年 | 6篇 |
1982年 | 7篇 |
1981年 | 10篇 |
1980年 | 6篇 |
1979年 | 11篇 |
1974年 | 4篇 |
1972年 | 7篇 |
1971年 | 5篇 |
1969年 | 7篇 |
1968年 | 4篇 |
排序方式: 共有3218条查询结果,搜索用时 888 毫秒
1.
Camille Veit 《Annales médico-psychologiques》2019,177(4):347-351
Objectives
This paper introduces some epistemology about mental health developments and how it leads to reconsider the landscape of clinical practices.Materials
From an epistemological point of view, the author reviews several writings about mental hygiene going back to the nineteenth century. It clarifies the common roots between mental hygiene and mental health. Then, the article examines the first World Health Organization's reports, that shed light on psychiatric and political issues in the middle of the twentieth century, which allows to reach out the foundations of mental health as a discursive practice.Results
The review of the developments from “mental hygiene” to “mental health” highlights a general climate of redesign on many points: Mental health as a discursive space is characterized by an expansion of its address field. It is not only addressed to specialists, psychiatrist and psychiatric patients, but also, and above all, to every citizen. Psychic suffering, as far as mental illness, is part of a larger whole including what preserves or deteriorates the proper functioning of an individual, within society. Mental health is at the crossroads of financial, political, citizen's rights and social interests. Contemporary mental health relies on the objectives of prevention and promotion. Clinical practices are organized by some discourses with mental health as a key word. At the turn of 2000s, French psychiatry has been impacted by many shuffles in health policies. However, the roots of these restructuring are not new, as they update an old interest in safeguarding public health, funds and welfare. Psychic suffering and mental illness recently enter the field of “psychic disability”. It brought social benefits such as financial assistance from the state. It may also contribute to the campaigns of awareness-raising and destigmatization among the public opinion. However, financial and subjective effects do not perfectly match. In other words, the benefits listed above should not lead to desert the listening of the users’ experience in its singularity.Conclusions
The developments of mental health point out a reorganization in the psychiatric field and open new clinical challenges. If the spaces of singularity and universal are in a permanent relationship, the political and economic sides cannot answer or evacuate the subjectivity posed by the subject and his suffering. It should lead to focus on a clinical practice driven by a subtle listening, which does not exclude psychopathology and recognizes the importance of alterity. 相似文献2.
A. Taytard J. F. Tessier J. G. Faugere J. Vergeret P. Freour 《European journal of epidemiology》1988,4(3):326-330
Professional exposure to vegetable dusts affect the respiratory function of the exposed subjects. A previous survey conducted in an industrial flour-mill demonstrated a higher frequency of respiratory symptoms in workers compared to a control group. Ten subjects employed in a work site particularly exposed to dust were studied. Each subject answered a questionnaire and performed on Mondays and Fridays, at the begenning and end of his work shift, a flow volume curve and an isocapnic hyperventilation test. The aerobiology of the professional environment was also measured. We noted: 1) in the flow volume curves: a drop in the FEV1 during the Monday morning shift, a significant difference between the FEV1 (p<0.05) and the MMEFR 25–75 (p<0.05) measured at 6 am on Monday and Friday, and between the MMEFR 25–75 values obtained at 12 noon on Monday and Friday (p<0.05). 2) after isocapnic hyperventilation, a significant drop in the MMEFR 25–75 at 6 am on Monday (p<0.01) and in the FEV1 and MMEFR 25–75 at 12 noon on Mondays (p<0.05), a significant drop in the FEV1 at 1 pm on Monday (p<0.01). 相似文献
3.
Efficacy of intensive multitherapy for patients with type 2 diabetes mellitus: a randomized controlled trial 总被引:1,自引:1,他引:0
下载免费PDF全文
![点击此处可从《Canadian Medical Association journal》网站下载免费的PDF全文](/ch/ext_images/free.gif)
4.
organized by J. P. Tessier 相似文献
5.
R Yassa C Nastase Y Camille M Henderson L Belzile F Beland 《The Journal of clinical psychiatry》1987,48(7):281-283
Although carbamazepine is known to cause hyponatremia, no previous reports have indicated an interaction between carbamazepine and a diuretic. Two patients are described who were treated with this combination and developed symptomatic hyponatremia, which cleared when both drugs were discontinued in one patient and when the diuretic was discontinued in the second patient. The possible mechanisms of action of carbamazepine-induced hyponatremia are discussed. 相似文献
6.
Andr Mas Hassan Jaaba Franois Schu Anna M. Belu Camille M. Kassis Richard W. Linton Joseph M. Desimone 《Macromolecular chemistry and physics.》1997,198(11):3737-3752
Homogeneous and stable layers were deposited through allylamine plasma polymerization (75 W, 100 Pa, 15 min) onto poly[(3-hydroxybutyric acid)-co-(3-hydroxyvaleric acid)] (91 : 9 wt.-%) (P(HB-co-9%HV)) film surfaces, XPS analysis using take-off angles of 20° and 70° and performed 10 days and 20 days after plasma treatment gives information on the composition (in atom%) of the modified surface: C, 62.74; N, 19.60; O, 17.65. The unexpected oxygen percentage is weaker if argon plasma pretreatment (25 W, 40 Pa, 5 min) is applied. Then, a succinct mechanism is proposed. The study of changes in element ratios and binding energy values shows that the majority of incorporated functional groups seem to be amide and imine groups. 相似文献
7.
Jesse Rosenthal Camille Hemlock David J. Hellerstein Phillip Yanowitch Karen Kasch Cynthia Schupak Lisa Samstag Arnold Winston 《Progress in neuro-psychopharmacology & biological psychiatry》1992,16(6):933-941
Rosenthal, Jesse et al. A Preliminary Study of Serotonergic Antidepressants in the Treatment of Dysthymia. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 1992, 16(6): 933–941.
1. 1. There is increasing evidence that antidepressants may alleviate symptoms of dysthymia, but few prior studies on selective serotonergic agents.
2. 2. Twenty patients meeting criteria for dysthymia, but not meeting criteria for major depression, received open label trials of a serotonergic antidepressant, either fluoxetine or trazodone.
3. 3. Seventeen (85%) completed three-month medication trials, and of these, twelve (70.6% of completers) responded to treatment. Seven (41.2% of completers) were still in remission on followup at five months.
4. 4. Both fluoxetine and trazodone were well tolerated in dysthymics, and showed similar short-term effectiveness in treating dysthymic symptoms.
8.
H. Caillet P. Cauquil Y. Ajavon G. Rouhana J. P. Verdier D. Azoulay H. Bismuth J. P. Tessier 《European radiology》1992,2(4):330-334
Ruptures of the hepatic artery and hepatic pseudoaneurysms (PA) are rare but serious complications of hepatic transplantation. We conducted a retrospective study of 640 liver transplantations performed in our institution for a variety of pathologies. After surgery, seven major arterial bleeds occurred (0.9%). Of these seven cases, there were due to hepatic artery rupture (HAr) and four to PA rupture; all confirmed at either surgery (six cases) or autopsy (one case). Five of the seven patients died. In all cases the transplantation was difficult. All vascular injuries but one were caused by sepsis and occurred either after an undetermined cause septicemic syndrome (five cases) or graft dysfunction (one case). The last vascular injury was biliary drainage related. Six of the seven patients had imaging studies. Sonography (five cases) found a sub-hepatic hypoechoic collection in three cases but failed to do so in two. Duplex doppler (three cases) failed in all three cases to demonstrate a PA. Computed tomography (three cases) showed one PA, one perihilar sub-hepatic collection and failed in one. Conventional angiography (three cases) depicted a PA in all three cases. At the present time, our practice is to perform systematic angiography in patients with undetermined cause septicemic syndrome to research a PA. And if angiography is normal, to then puncture systematically any sub-hepatic collection to determine the bacteriological nature of this collection.
Correspondence to: H. Caillet 相似文献
9.
10.
As part of a world survey of the habits, knowledge and attitudes of medical students regarding tobacco we report a study in 15 medical schools from nine Asian countries. Some 1646 first year and 1587 final year students were included, of whom 59% were male. The prevalence of daily smoking in males was 4% in first year and 11% in final year; of occasional smoking 18% and 24% respectively, both with considerable variations between countries. The rates were very low in women. Male exsmokers varied from 3% to 24% in different centres. Overall, 33% of smokers had made a serious attempt to quit; 44% expected to have succeeded within 5 years. Over 80% of non- or exsmokers, but only 60% of smokers, thought smoking was harmful to health. There was gross underestimation of tobacco's causal role in a number of important diseases, e.g. coronary artery disease, peripheral vascular disease, emphysema, bladder cancer and neonatal mortality. There were notable defects both in training and in motivation to counsel smoking patients. There was only partial knowledge of legislative and other measures to discourage smoking, e.g. only 44% of final year students (26% of smokers) thought increased taxation an important measure. In knowledge and attitudes there was little difference between the sexes, but in most aspects smokers had notably lower scores. 相似文献