全文获取类型
收费全文 | 1871篇 |
免费 | 250篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 22篇 |
儿科学 | 62篇 |
妇产科学 | 26篇 |
基础医学 | 181篇 |
口腔科学 | 44篇 |
临床医学 | 278篇 |
内科学 | 416篇 |
皮肤病学 | 121篇 |
神经病学 | 117篇 |
特种医学 | 138篇 |
外科学 | 303篇 |
综合类 | 110篇 |
现状与发展 | 30篇 |
一般理论 | 7篇 |
预防医学 | 81篇 |
眼科学 | 15篇 |
药学 | 78篇 |
中国医学 | 3篇 |
肿瘤学 | 107篇 |
出版年
2024年 | 15篇 |
2023年 | 178篇 |
2022年 | 12篇 |
2021年 | 19篇 |
2020年 | 58篇 |
2019年 | 27篇 |
2018年 | 55篇 |
2017年 | 51篇 |
2016年 | 46篇 |
2015年 | 63篇 |
2014年 | 91篇 |
2013年 | 79篇 |
2012年 | 55篇 |
2011年 | 62篇 |
2010年 | 91篇 |
2009年 | 105篇 |
2008年 | 55篇 |
2007年 | 81篇 |
2006年 | 59篇 |
2005年 | 63篇 |
2004年 | 38篇 |
2003年 | 38篇 |
2002年 | 44篇 |
2001年 | 40篇 |
2000年 | 41篇 |
1999年 | 42篇 |
1998年 | 44篇 |
1997年 | 56篇 |
1996年 | 44篇 |
1995年 | 48篇 |
1994年 | 35篇 |
1993年 | 40篇 |
1992年 | 23篇 |
1991年 | 23篇 |
1990年 | 17篇 |
1989年 | 29篇 |
1988年 | 29篇 |
1987年 | 23篇 |
1986年 | 13篇 |
1985年 | 19篇 |
1984年 | 10篇 |
1982年 | 11篇 |
1981年 | 13篇 |
1980年 | 13篇 |
1978年 | 13篇 |
1976年 | 19篇 |
1975年 | 16篇 |
1974年 | 13篇 |
1973年 | 10篇 |
1945年 | 9篇 |
排序方式: 共有2139条查询结果,搜索用时 849 毫秒
1.
A mixed‐method study of effects of a therapeutic play intervention for children on parental anxiety and parents' perceptions of the intervention
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
2.
Monocyte chemotactic protein expression during schistosome egg granuloma formation. Sequence of production, localization, contribution, and regulation. 总被引:11,自引:6,他引:5
下载免费PDF全文
![点击此处可从《The American journal of pathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
S. W. Chensue K. S. Warmington N. W. Lukacs P. M. Lincoln M. D. Burdick R. M. Strieter S. L. Kunkel 《The American journal of pathology》1995,146(1):130-138
The present study explored the role of murine monocyte chemotactic protein (MCP) in the T cell-mediated hypersensitive granulomatous response to Schistosoma mansoni eggs. The study examined the time course of local production, contribution to cellular infiltration, and the role of T cells in endogenous regulation. Synchronized pulmonary granulomas were induced under conditions of primary and secondary states of immunity. Primer-directed polymerase chain reaction analysis showed increased MCP mRNA expression in granulomatous lungs, mainly in the secondary response. Levels of MCP were measured by enzyme-linked immunosorbent assay in cultures of intact granulomas. Spontaneous MCP production was modest in primary granuloma cultures, reaching a maximum of 5.7 +/- 0.9 ng/ml by 16 days. In contrast, the secondary response showed augmented and accelerated production, achieving 13 +/- 2.0 ng/ml by 2 days. Immunohistochemical staining revealed the strongest MCP expression within microvascular adventitial cells or pericytes as well as in scattered mononuclear cells associated with granulomas. Staining was not detected in normal lungs. Passive immunization with anti-MCP-1 antibodies caused a 40% reduction in the secondary granuloma area but did not significantly affect the primary response. With adoptive cell transfer and T cell subset depletion, it was shown that Thy-1+ and CD5+ cells augmented, whereas CD8+ cells appeared to impair, MCP production. This provides direct evidence that MCP is involved in secondary Th2-mediated response to schistosome eggs and is subject to regulation by T cells. 相似文献
3.
Hysterosalpingography was performed in 31 patients by means of a low-dose scanning-beam digital radiographic system. The technique permits adequate evaluation of gynecologic abnormalities while allowing significant reduction in radiation: 2.4-mR (6.1 X 10(-7) C/kg) exposure to the skin and 0.7-mrad (7 X 10(-6) Gy) mean dose to the ovaries per image obtained. Sixteen patients demonstrated readily recognizable and documented abnormalities, corroborated by laparoscopy, laparotomy, or other supportive evidence. 相似文献
4.
5.
6.
7.
8.
Solitary bronchioloalveolar carcinoma: CT criteria 总被引:14,自引:0,他引:14
Kuhlman JE; Fishman EK; Kuhajda FP; Meziane MM; Khouri NF; Zerhouni EA; Siegelman SS 《Radiology》1988,167(2):379-382
The computed tomographic (CT) scans of 30 patients with solitary bronchioloalveolar carcinoma were reviewed. Common features at CT included the peripheral or subpleural location of a pulmonary mass (25 cases), pseudocavitation (18 cases), heterogeneous attenuation (17 cases), irregular margins forming a star pattern (22 cases), and pleural tags (21 cases). Using these CT criteria, four independent observers attempted to identify cases of bronchioloalveolar carcinoma from a larger sample of lung cancers and benign lesions by categorizing a series of test cases into four probability categories. Although the bronchioloalveolar carcinomas were correctly ranked in the two highest probability categories 75% of the time (in 45 of 60 cases), there was considerable overlap with other lung lesions, particularly with adenocarcinoma and large cell undifferentiated carcinoma. However, even though the typical features of bronchioloalveolar carcinoma are not invariable or highly specific, they are characteristic enough to suggest the diagnosis. 相似文献
9.
10.