全文获取类型
收费全文 | 36309篇 |
免费 | 2384篇 |
国内免费 | 72篇 |
专业分类
耳鼻咽喉 | 643篇 |
儿科学 | 1368篇 |
妇产科学 | 1305篇 |
基础医学 | 5340篇 |
口腔科学 | 794篇 |
临床医学 | 3105篇 |
内科学 | 7266篇 |
皮肤病学 | 801篇 |
神经病学 | 3549篇 |
特种医学 | 1535篇 |
外国民族医学 | 16篇 |
外科学 | 5341篇 |
综合类 | 226篇 |
一般理论 | 6篇 |
预防医学 | 2241篇 |
眼科学 | 772篇 |
药学 | 1891篇 |
中国医学 | 26篇 |
肿瘤学 | 2540篇 |
出版年
2022年 | 236篇 |
2021年 | 479篇 |
2020年 | 348篇 |
2019年 | 458篇 |
2018年 | 582篇 |
2017年 | 480篇 |
2016年 | 651篇 |
2015年 | 636篇 |
2014年 | 876篇 |
2013年 | 1165篇 |
2012年 | 1637篇 |
2011年 | 1760篇 |
2010年 | 906篇 |
2009年 | 926篇 |
2008年 | 1569篇 |
2007年 | 1715篇 |
2006年 | 1637篇 |
2005年 | 1606篇 |
2004年 | 1402篇 |
2003年 | 1405篇 |
2002年 | 1278篇 |
2001年 | 1178篇 |
2000年 | 1251篇 |
1999年 | 1069篇 |
1998年 | 455篇 |
1997年 | 355篇 |
1996年 | 298篇 |
1995年 | 280篇 |
1994年 | 257篇 |
1993年 | 254篇 |
1992年 | 694篇 |
1991年 | 737篇 |
1990年 | 714篇 |
1989年 | 602篇 |
1988年 | 567篇 |
1987年 | 576篇 |
1986年 | 590篇 |
1985年 | 584篇 |
1984年 | 408篇 |
1983年 | 343篇 |
1982年 | 230篇 |
1981年 | 226篇 |
1979年 | 413篇 |
1978年 | 288篇 |
1977年 | 263篇 |
1976年 | 245篇 |
1975年 | 266篇 |
1974年 | 321篇 |
1973年 | 276篇 |
1972年 | 251篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
1.
Mette Nissen Tiina‐Mari Ikheimo Jukka Huttunen Ville Leinonen Henna‐Kaisa Jyrkknen Mikael von und zu Fraunberg 《Neuromodulation》2021,24(1):102-111
ObjectiveSpinal cord stimulation (SCS) is an effective treatment in failed back surgery syndrome (FBSS). We studied the effect of preimplantation opioid use on SCS outcome and the effect of SCS on opioid use during a two-year follow-up period.Materials and methodsThe study cohort included 211 consecutive FBSS patients who underwent an SCS trial from January 1997 to March 2014. Participants were divided into groups, which were as follows: 1) SCS trial only (n = 47), 2) successful SCS (implanted and in use throughout the two-year follow-up period, n = 131), and 3) unsuccessful SCS (implanted but later explanted or revised due to inadequate pain relief, n = 29). Patients who underwent explantation for other reasons (n = 4) were excluded. Opioid purchase data from January 1995 to March 2016 were retrieved from national registries.ResultsHigher preimplantation opioid doses associated with unsuccessful SCS (ROC: AUC = 0.66, p = 0.009), with 35 morphine milligram equivalents (MME)/day as the optimal cutoff value. All opioids were discontinued in 23% of patients with successful SCS, but in none of the patients with unsuccessful SCS (p = 0.004). Strong opioids were discontinued in 39% of patients with successful SCS, but in none of the patients with unsuccessful SCS (p = 0.04). Mean opioid dose escalated from 18 ± 4 MME/day to 36 ± 6 MME/day with successful SCS and from 22 ± 8 MME/day to 82 ± 21 MME/day with unsuccessful SCS (p < 0.001).ConclusionsHigher preimplantation opioid doses were associated with SCS failure, suggesting the need for opioid tapering before implantation. With continuous SCS therapy and no explantation or revision due to inadequate pain relief, 39% of FBSS patients discontinued strong opioids, and 23% discontinued all opioids. This indicates that SCS should be considered before detrimental dose escalation. 相似文献
2.
Hommes Franziska Mohsenpour Amir Kropff Dana Pilgram Lisa Matusall Svenja von Philipsborn Peter Sell Kerstin 《Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz》2022,65(1):96-106
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz - Akteure der öffentlichen Gesundheit (Public Health) tragen wesentlich zu Gesundheitsschutz, -förderung und... 相似文献
3.
4.
Neurofibromatosis Type 1 Diagnosed in a Child Based on Multiple Juvenile Xanthogranulomas and Juvenile Myelomonocytic Leukemia 下载免费PDF全文
Sune R. R. Jans M.D. Eckhard Schomerus M.D. Anette Bygum M.D. 《Pediatric dermatology》2015,32(1):e29-e32
An association between juvenile xanthogranuloma (JXG), neurofibromatosis type 1 (NF1), and juvenile myelomonocytic leukemia (JMML) has been described in the literature but has only been documented in approximately 20 cases. We diagnosed a patient with NF1 at 25 months of age, before any cutaneous stigmata of this disease had appeared, because we decided to screen for the NF1 gene mutation because of his presentation with multiple JXGs and moderate macrocephaly (2.5 standard deviations) at 9 months of age and JMML diagnosed at 20 months of age. The child is well today after treatment with chemotherapy and allogenic bone marrow transplantation. With increased awareness, patients with JXG and NF1 who develop symptoms possibly related to JMML, such as paleness, skin bleeding, cough, unexplained fever, and hepatosplenomegaly, should be further evaluated. We also emphasize that multiple JXG lesions can be an early marker of NF1. 相似文献
5.
6.
7.
Die Unfallchirurgie - Zur Diagnostik von Schultergelenkerkrankungen wird routinemäßig die Magnetresonanztomographie (MRT) durchgeführt. Diese kann entsprechend der klinischen... 相似文献
8.
9.
10.